Neural stem cell quiescence and stemness are molecularly distinct outputs of the Notch3 signalling cascade in the vertebrate adult brain

Area-Specific Regulation of Quiescent Neural Stem Cells by Notch3 in the Adult Mouse Subependymal Zone

(2017) Hiroki Kawai et al.   JOURNAL OF NEUROSCIENCE

Temporal effects of Notch signaling and potential cooperation with multiple downstream effectors on adenohypophysis cell specification in zebrafish

(2016) Yoshinari Nakahara et al.   GENES TO CELLS

Return to quiescence of mouse neural stem cells by degradation of a proactivation protein

(2016) Noelia Urbán et al.   SCIENCE

Neural Stem Cells and Nutrients: Poised Between Quiescence and Exhaustion

(2016) Virve Cavallucci et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Cancer-Associated Fibroblasts Regulate Tumor-Initiating Cell Plasticity in Hepatocellular Carcinoma through c-Met/FRA1/HEY1 Signaling

(2016) Eunice Yuen Ting Lau et al.   Cell Reports

A Nuclear Role for miR-9 and Argonaute Proteins in Balancing Quiescent and Activated Neural Stem Cell States

(2016) Shauna Katz et al.   Cell Reports

A MultiSite Gateway Toolkit for Rapid Cloning of Vertebrate Expression Constructs with Diverse Research Applications

(2016) Daniel K. Fowler et al.   PLoS One

Large-scale live imaging of adult neural stem cells in their endogenous niche

(2015) Nicolas Dray et al.   DEVELOPMENT

Distinct Notch signaling outputs pattern the developing arterial system

(2014) A. Quillien et al.   DEVELOPMENT

Spatial Regionalization and Heterochrony in the Formation of Adult Pallial Neural Stem Cells

(2014) Lara Dirian et al.   DEVELOPMENTAL CELL

Differential regulation of Hes/Hey genes during inner ear development

(2014) Jelena Petrovic et al.   Developmental Neurobiology

Direct cell–cell contact with the vascular niche maintains quiescent neural stem cells

(2014) Cristina Ottone et al.   NATURE CELL BIOLOGY

A Transcriptional Mechanism Integrating Inputs from Extracellular Signals to Activate Hippocampal Stem Cells

(2014) Jimena Andersen et al.   NEURON

Prospective Identification and Purification of Quiescent Adult Neural Stem Cells from Their In Vivo Niche

(2014) Paolo Codega et al.   NEURON

Notch3 signaling gates cell cycle entry and limits neural stem cell amplification in the adult pallium

(2013) A. Alunni et al.   DEVELOPMENT

notch3 is essential for oligodendrocyte development and vascular integrity in zebrafish

(2013) A. Zaucker et al.   Disease Models & Mechanisms

Dynamic binding of RBPJ is determined by Notch signaling status

(2013) D. Castel et al.   GENES & DEVELOPMENT

Epigenomic enhancer annotation reveals a key role for NFIX in neural stem cell quiescence

(2013) B. Martynoga et al.   GENES & DEVELOPMENT

Transcriptional repression of Bmp2 by p21Waf1/Cip1 links quiescence to neural stem cell maintenance

(2013) Eva Porlan et al.   NATURE NEUROSCIENCE

Enriching the gene set analysis of genome-wide data by incorporating directionality of gene expression and combining statistical hypotheses and methods

(2013) Leif Väremo et al.   NUCLEIC ACIDS RESEARCH

Dll1 maintains quiescence of adult neural stem cells and segregates asymmetrically during mitosis

(2013) Daichi Kawaguchi et al.   Nature Communications

FOXO3 Shares Common Targets with ASCL1 Genome-wide and Inhibits ASCL1-Dependent Neurogenesis

(2013) Ashley E. Webb et al.   Cell Reports

Staying alive

(2012) James R. Valcourt et al.   CELL CYCLE

Adult Neural Stem Cells Bridge Their Niche

(2012) Luis C. Fuentealba et al.   Cell Stem Cell

Cyclin-Dependent Kinase Inhibitor p21 Controls Adult Neural Stem Cell Expansion by Regulating Sox2 Gene Expression

(2012) M. Ángeles Marqués-Torrejón et al.   Cell Stem Cell

Different levels of Notch signaling regulate quiescence, renewal and differentiation in pancreatic endocrine progenitors

(2012) N. Ninov et al.   DEVELOPMENT

Neurogenic Subventricular Zone Stem/Progenitor Cells Are Notch1-Dependent in Their Active But Not Quiescent State

(2012) O. Basak et al.   JOURNAL OF NEUROSCIENCE

Ten Years of Pathway Analysis: Current Approaches and Outstanding Challenges

(2012) Purvesh Khatri et al.   PLoS Computational Biology

Neural stem cell deforestation as the main force driving the age-related decline in adult hippocampal neurogenesis

(2011) Juan M. Encinas et al.   BEHAVIOURAL BRAIN RESEARCH

Proliferative Neural Stem Cells Have High Endogenous ROS Levels that Regulate Self-Renewal and Neurogenesis in a PI3K/Akt-Dependant Manner

(2011) Janel E. Le Belle et al.   Cell Stem Cell

Division-Coupled Astrocytic Differentiation and Age-Related Depletion of Neural Stem Cells in the Adult Hippocampus

(2011) Juan M. Encinas et al.   Cell Stem Cell

Clonal analysis by distinct viral vectors identifies bona fide neural stem cells in the adult zebrafish telencephalon and characterizes their division properties and fate

(2011) I. Rothenaigner et al.   DEVELOPMENT

Jagged 1 regulates the restriction of Sox2 expression in the developing chicken inner ear: a mechanism for sensory organ specification

(2011) J. Neves et al.   DEVELOPMENT

Interplay between FGF2 and BMP controls the self-renewal, dormancy and differentiation of rat neural stem cells

(2011) Y. Sun et al.   JOURNAL OF CELL SCIENCE

A comparison of InVivoStat with other statistical software packages for analysis of data generated from animal experiments

(2011) Robin A Clark et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Adult Neurogenesis in the Mammalian Brain: Significant Answers and Significant Questions

(2011) Guo-li Ming et al.   NEURON

Concise Review: Quiescent and Active States of Endogenous Adult Neural Stem Cells: Identification and Characterization

(2011) Ya-Zhou Wang et al.   STEM CELLS

A Critical Requirement for Notch Signaling in Maintenance of the Quiescent Skeletal Muscle Stem Cell State

(2011) Philippos Mourikis et al.   STEM CELLS

Signaling through BMPR-IA Regulates Quiescence and Long-Term Activity of Neural Stem Cells in the Adult Hippocampus

(2010) Helena Mira et al.   Cell Stem Cell

RBPJ -Dependent Signaling Is Essential for Long-Term Maintenance of Neural Stem Cells in the Adult Hippocampus

(2010) O. Ehm et al.   JOURNAL OF NEUROSCIENCE

Notch Activity Levels Control the Balance between Quiescence and Recruitment of Adult Neural Stem Cells

(2010) P. Chapouton et al.   JOURNAL OF NEUROSCIENCE

Notch1 Is Required for Maintenance of the Reservoir of Adult Hippocampal Stem Cells

(2010) J. L. Ables et al.   JOURNAL OF NEUROSCIENCE

Essential Roles of Notch Signaling in Maintenance of Neural Stem Cells in Developing and Adult Brains

(2010) I. Imayoshi et al.   JOURNAL OF NEUROSCIENCE

The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism

(2009) Raphael Kopan et al.   CELL

FoxOs Cooperatively Regulate Diverse Pathways Governing Neural Stem Cell Homeostasis

(2009) Ji-hye Paik et al.   Cell Stem Cell

FoxO3 Regulates Neural Stem Cell Homeostasis

(2009) Valérie M. Renault et al.   Cell Stem Cell

HeyL regulates the number of TrkC neurons in dorsal root ganglia

(2009) Abhishek Mukhopadhyay et al.   DEVELOPMENTAL BIOLOGY

Hippocampal development and neural stem cell maintenance require Sox2-dependent regulation of Shh

(2009) Rebecca Favaro et al.   NATURE NEUROSCIENCE

The nuclear receptor tailless is required for neurogenesis in the adult subventricular zone

(2008) H.-K. Liu et al.   GENES & DEVELOPMENT

Noggin Expands Neural Stem Cells in the Adult Hippocampus

(2008) M. A. Bonaguidi et al.   JOURNAL OF NEUROSCIENCE

Using RSAT to scan genome sequences for transcription factor binding sites and cis-regulatory modules

(2008) Jean-Valery Turatsinze et al.   Nature Protocols