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Mechanisms of the H2-and transfer hydrogenation of polar bonds catalyzed by iron group hydrides

Journal

DALTON TRANSACTIONS
Volume 47, Issue 32, Pages 10809-10826

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c8dt01804a

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Funding

  1. Natural Sciences and Engineering Research Council of Canada
  2. Canada Council for the Arts
  3. Compute Canada
  4. Sharcnet
  5. DFG [IRTG 2027]
  6. University of Toronto for the Munster-Toronto Graduate Training Program

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This perspective reviews our efforts to use a mechanism-based approach to develop catalysts for the asymmetric hydrogenation of prochiral ketones and imines. A goal is to discover catalysts based on the abundant 3d transition metals, particularly iron.

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