Repeated stimulation by LPS promotes the senescence of DPSCs via TLR4/MyD88-NF-κB-p53/p21 signaling

Effects of Differentiation and Antisenescence from BMSCs to Hepatocy-Like Cells of the PAAm-IGF-1/TNF-α Biomaterial

(2016) Runcai Yang et al.   ACS Applied Materials & Interfaces

Probucol inhibits LPS-induced microglia activation and ameliorates brain ischemic injury in normal and hyperlipidemic mice

(2016) Yeon Suk Jung et al.   ACTA PHARMACOLOGICA SINICA

Cartilage oligomeric matrix protein prevents vascular aging and vascular smooth muscle cells senescence

(2016) Meili Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

BRD7 plays an anti-inflammatory role during early acute inflammation by inhibiting activation of the NF-кB signaling pathway

(2016) Ran Zhao et al.   Cellular & Molecular Immunology

Lamin in inflammation and aging

(2016) Joseph R Tran et al.   CURRENT OPINION IN CELL BIOLOGY

Elevated level of pro inflammatory cytokine and chemokine expression in chicken bone marrow and monocyte derived dendritic cells following LPS induced maturation

(2016) Semmannan Kalaiyarasu et al.   CYTOKINE

Dioscin alleviates dimethylnitrosamine-induced acute liver injury through regulating apoptosis, oxidative stress and inflammation

(2016) Weixin Zhang et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

FGF21 represses cerebrovascular aging via improving mitochondrial biogenesis and inhibiting p53 signaling pathway in an AMPK-dependent manner

(2016) Xiao-Mei Wang et al.   EXPERIMENTAL CELL RESEARCH

p65 down-regulates DEPTOR expression in response to LPS stimulation in hepatocytes

(2016) Xiaoling Yu et al.   GENE

Dioscin reduces lipopolysaccharide-induced inflammatory liver injury via regulating TLR4/MyD88 signal pathway

(2016) Hong Yao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Microenvironmental Views on Mesenchymal Stem Cell Differentiation in Aging

(2016) B.D. Sui et al.   JOURNAL OF DENTAL RESEARCH

The role of MyD88- and TRIF-dependent signaling in monophosphoryl lipid A-induced expansion and recruitment of innate immunocytes

(2016) Antonio Hernandez et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Mesenchymal stem cell-derived inflammatory fibroblasts mediate interstitial fibrosis in the aging heart

(2016) JoAnn Trial et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Foxp3 is a key downstream regulator of p53-mediated cellular senescence

(2016) J-E Kim et al.   ONCOGENE

Anti-Inflammatory Effects of a Pomegranate Leaf Extract in LPS-Induced Peritonitis

(2016) Lucia Marques et al.   PLANTA MEDICA

The Effect of Tumour Necrosis Factor-α on Periodontal Ligament Stem Cell Differentiation and the Related Signaling Pathways

(2016) Xiaochen Liu et al.   Current Stem Cell Research & Therapy

Tetrahydroanthraquinone Derivative (±)-4-Deoxyaustrocortilutein Induces Cell Cycle Arrest and Apoptosis in Melanoma Cells via Upregulation of p21 and p53 and Downregulation of NF-kappaB

(2016) Miroslav Genov et al.   Journal of Cancer

Cannabidiol Modulates the Immunophenotype and Inhibits the Activation of the Inflammasome in Human Gingival Mesenchymal Stem Cells

(2016) Rosaliana Libro et al.   Frontiers in Physiology

SIRT1 alleviates senescence of degenerative human intervertebral disc cartilage endo-plate cells via the p53/p21 pathway

(2016) Nian Zhou et al.   Scientific Reports

Transcriptome sequencing wide functional analysis of human mesenchymal stem cells in response to TLR4 ligand

(2016) Sun Hwa Kim et al.   Scientific Reports

Screening of a kinase library reveals novel pro-senescence kinases and their common NF-κB-dependent transcriptional program

(2015) Mylène Ferrand et al.   Aging-US

Diosmin downregulates the expression of T cell receptors, pro-inflammatory cytokines and NF-κB activation against LPS-induced acute lung injury in mice

(2015) Faisal Imam et al.   PHARMACOLOGICAL RESEARCH

A composite scaffold of MSC affinity peptide-modified demineralized bone matrix particles and chitosan hydrogel for cartilage regeneration

(2015) Qingyang Meng et al.   Scientific Reports

Nascent osteoblast matrix inhibits osteogenesis of human mesenchymal stem cells in vitro

(2015) Catherine M. Kolf et al.   Stem Cell Research & Therapy

Repeated lipopolysaccharide stimulation promotes cellular senescence in human dental pulp stem cells (DPSCs)

(2014) Xingmei Feng et al.   CELL AND TISSUE RESEARCH

Lipopolysaccharide stimulation improves the odontoblastic differentiation of human dental pulp cells

(2014) YIHUA HUANG et al.   Molecular Medicine Reports

Senescence in adipose-derived stem cells and its implications in nerve regeneration

(2014) Cristina Mantovani et al.   Neural Regeneration Research

Lipopolysaccharide induced LOX-1 expression via TLR4/MyD88/ROS activated p38MAPK-NF-κB pathway

(2014) Wenwen Zhao et al.   VASCULAR PHARMACOLOGY

Downregulated microRNA-32 expression induced by high glucose inhibits cell cycle progression via PTEN upregulation and Akt inactivation in bone marrow-derived mesenchymal stem cells

(2013) Guiying Zhu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Effect of isolation methodology on stem cell properties and multilineage differentiation potential of human dental pulp stem cells

(2013) P. Hilkens et al.   CELL AND TISSUE RESEARCH

Age-Dependent Impaired Neurogenic Differentiation Capacity of Dental Stem Cell is Associated with Wnt/β-Catenin Signaling

(2013) Xingmei Feng et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Mesenchymal stem cells as a vector for the inflammatory prostate microenvironment

(2013) W Nathaniel Brennen et al.   ENDOCRINE-RELATED CANCER

p21 is Associated with the Proliferation and Apoptosis of Bone Marrow-derived Mesenchymal Stem Cells from Non-obese Diabetic Mice

(2013) Z. Gu et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

Adenosine A1 receptor stimulation enhances osteogenic differentiation of human dental pulp-derived mesenchymal stem cells via WNT signaling

(2013) Iolanda D'Alimonte et al.   Stem Cell Research

Abnormal Lung Aging in Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis

(2012) Rosa Faner et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

TLR agonists are highly effective at eliciting functional memory CTLs of effector memory phenotype in peptide immunization

(2012) Kendra Smyth et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Inflammation-mediated abrogation of androgen signaling: An in vitro model of prostate cell inflammation

(2012) Bilge Debelec-Butuner et al.   MOLECULAR CARCINOGENESIS

Repeated Lipopolysaccharide Stimulation Induces Cellular Senescence in BV2 Cells

(2012) Hong-Mei Yu et al.   NEUROIMMUNOMODULATION

p53-mediated induction of Noxa and p53AIP1 requires NFκB

(2011) Jim O’Prey et al.   CELL CYCLE

Retracted: Pro-inflammatory cytokines induce odontogenic differentiation of dental pulp-derived stem cells

(2011) Xuechao Yang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Activation of nuclear factor-kappa B signalling promotes cellular senescence

(2011) E Rovillain et al.   ONCOGENE

MAPK Signaling Is Required for LPS-induced VEGF in Pulp Stem Cells

(2010) T.M. Botero et al.   JOURNAL OF DENTAL RESEARCH

Stem/progenitor cells from inflamed human dental pulp retain tissue regeneration potential

(2010) Dominick J Alongi et al.   Regenerative Medicine

Protocols to detect senescence-associated beta-galactosidase (SA-βgal) activity, a biomarker of senescent cells in culture and in vivo

(2009) Florence Debacq-Chainiaux et al.   Nature Protocols

Identification of Oxidative Stress and Toll-like Receptor 4 Signaling as a Key Pathway of Acute Lung Injury

(2008) Yumiko Imai et al.   CELL

Molecular biology of inflammation and sepsis: A primer*

(2008) Ismail Cinel et al.   CRITICAL CARE MEDICINE

LPS/TLR4 signal transduction pathway

(2008) Yong-Chen Lu et al.   CYTOKINE