Comprehensive review of the detection methods for synthetic cannabinoids and cathinones
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Comprehensive review of the detection methods for synthetic cannabinoids and cathinones
Authors
Keywords
Synthetic cannabinoids, Cannabimimetics, Cathinones, GC–MS-MS, LC–MS-MS, Analytical methods
Journal
Forensic Toxicology
Volume 33, Issue 2, Pages 175-194
Publisher
Springer Nature
Online
2015-03-05
DOI
10.1007/s11419-015-0270-0
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- A liquid chromatography–mass spectrometry method based on class characteristic fragmentation pathways to detect the class of indole-derivative synthetic cannabinoids in biological samples
- (2014) Monica Mazzarino et al. ANALYTICA CHIMICA ACTA
- 3,4-Methylenedioxypyrovalerone (MDPV) and metabolites quantification in human and rat plasma by liquid chromatography–high resolution mass spectrometry
- (2014) Sebastien Anizan et al. ANALYTICA CHIMICA ACTA
- Analytical Differentiation of 1-Alkyl-3-acylindoles and 1-Acyl-3-alkylindoles: Isomeric Synthetic Cannabinoids
- (2014) Jack DeRuiter et al. ANALYTICAL CHEMISTRY
- Validation of the only commercially available immunoassay for synthetic cathinones in urine: Randox Drugs of Abuse V Biochip Array Technology
- (2014) Kayla N. Ellefsen et al. Drug Testing and Analysis
- A mixed MDPV and benzodiazepine intoxication in a chronic drug abuser: Determination of MDPV metabolites by LC–HRMS and discussion of the case
- (2014) Elisabetta Bertol et al. FORENSIC SCIENCE INTERNATIONAL
- 3-Naphthoylindazoles and 2-naphthoylbenzoimidazoles as novel chemical groups of synthetic cannabinoids: Chemical structure elucidation, analytical characteristics and identification of the first representatives in smoke mixtures
- (2014) Vadim Shevyrin et al. FORENSIC SCIENCE INTERNATIONAL
- A structure–reactivity relationship driven approach to the identification of a color test protocol for the presumptive indication of synthetic cannabimimetic drugs of abuse
- (2014) Richard C.A. Isaacs FORENSIC SCIENCE INTERNATIONAL
- Identification and quantitation of a new cathinone designer drug PV9 in an “aroma liquid” product, antemortem whole blood and urine specimens, and a postmortem whole blood specimen in a fatal poisoning case
- (2014) Koutaro Hasegawa et al. Forensic Toxicology
- Postmortem distribution of α-pyrrolidinovalerophenone and its metabolite in body fluids and solid tissues in a fatal poisoning case measured by LC–MS–MS with the standard addition method
- (2014) Koutaro Hasegawa et al. Forensic Toxicology
- Chemical analysis of a benzofuran derivative, 2-(2-ethylaminopropyl)benzofuran (2-EAPB), eight synthetic cannabinoids, five cathinone derivatives, and five other designer drugs newly detected in illegal products
- (2014) Nahoko Uchiyama et al. Forensic Toxicology
- Fragmentation differences in the EI spectra of three synthetic cannabinoid positional isomers: JWH-250, JWH-302, and JWH-201
- (2014) Dana N. Harris et al. INTERNATIONAL JOURNAL OF MASS SPECTROMETRY
- Four Postmortem Case Reports with Quantitative Detection of the Synthetic Cannabinoid, 5F-PB-22
- (2014) George Behonick et al. JOURNAL OF ANALYTICAL TOXICOLOGY
- Testing for Designer Stimulants: Metabolic Profiles of 16 Synthetic Cathinones Excreted Free in Human Urine
- (2014) Victor Uralets et al. JOURNAL OF ANALYTICAL TOXICOLOGY
- Simultaneous quantification of 20 synthetic cannabinoids and 21 metabolites, and semi-quantification of 12 alkyl hydroxy metabolites in human urine by liquid chromatography–tandem mass spectrometry
- (2014) Karl B. Scheidweiler et al. JOURNAL OF CHROMATOGRAPHY A
- Postmortem distribution of α-pyrrolidinobutiophenone in body fluids and solid tissues of a human cadaver
- (2014) Amin Wurita et al. Legal Medicine
- Quantitative analysis of 3,4-dimethylmethcathinone in blood and urine by liquid chromatography–tandem mass spectrometry in a fatal case
- (2014) Kiyotaka Usui et al. Legal Medicine
- Synthetic cannabinoids: Analysis and metabolites
- (2014) Mahmoud A. ElSohly et al. LIFE SCIENCES
- LC/ESI-MS/MS method for quantification of 28 synthetic cannabinoids in neat oral fluid and its application to preliminary studies on their detection windows
- (2013) Stefan Kneisel et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- In silico and in vitro metabolism studies support identification of designer drugs in human urine by liquid chromatography/quadrupole-time-of-flight mass spectrometry
- (2013) Elli Tyrkkö et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Simultaneous quantification of 28 synthetic cathinones and metabolites in urine by liquid chromatography-high resolution mass spectrometry
- (2013) Marta Concheiro et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Qualitative Confirmation of 9 Synthetic Cannabinoids and 20 Metabolites in Human Urine Using LC–MS/MS and Library Search
- (2013) Ariane Wohlfarth et al. ANALYTICAL CHEMISTRY
- Psychoactive substances—Some new, some old: A scan of the situation in the U.S.
- (2013) Jane Carlisle Maxwell DRUG AND ALCOHOL DEPENDENCE
- Cross-reactivity of designer drugs, including cathinone derivatives, in commercial enzyme-linked immunosorbent assays
- (2013) Madeleine J. Swortwood et al. Drug Testing and Analysis
- Acute intoxication by synthetic cannabinoids - Four case reports
- (2013) Maren Hermanns-Clausen et al. Drug Testing and Analysis
- Analysis of UR-144 and its pyrolysis product in blood and their metabolites in urine
- (2013) Piotr Adamowicz et al. FORENSIC SCIENCE INTERNATIONAL
- Analysis of 4-MEC in biological and non-biological material—Three case reports
- (2013) Dominika Gil et al. FORENSIC SCIENCE INTERNATIONAL
- Forensic investigation of K2, Spice, and “bath salt” commercial preparations: A three-year study of new designer drug products containing synthetic cannabinoid, stimulant, and hallucinogenic compounds
- (2013) Kathryn A. Seely et al. FORENSIC SCIENCE INTERNATIONAL
- Two new-type cannabimimetic quinolinyl carboxylates, QUPIC and QUCHIC, two new cannabimimetic carboxamide derivatives, ADB-FUBINACA and ADBICA, and five synthetic cannabinoids detected with a thiophene derivative α-PVT and an opioid receptor agonist AH-7921 identified in illegal products
- (2013) Nahoko Uchiyama et al. Forensic Toxicology
- Metabolism of the newly encountered designer drug α-pyrrolidinovalerophenone in humans: identification and quantitation of urinary metabolites
- (2013) Noriaki Shima et al. Forensic Toxicology
- Time-course profile of urinary excretion of intravenously administered α-pyrrolidinovalerophenone and α-pyrrolidinobutiophenone in a human
- (2013) Akira Namera et al. Forensic Toxicology
- A fatal case of 3,4-methylenedioxypyrovalerone poisoning: coexistence of α-pyrrolidinobutiophenone and α-pyrrolidinovalerophenone in blood and/or hair
- (2013) Akira Namera et al. Forensic Toxicology
- A fatal case of MAM-2201 poisoning
- (2013) Takeshi Saito et al. Forensic Toxicology
- Thermal degradation of a new synthetic cannabinoid QUPIC during analysis by gas chromatography–mass spectrometry
- (2013) Kenji Tsujikawa et al. Forensic Toxicology
- Synthetic cannabinoids abused in South Korea: drug identifications by the National Forensic Service from 2009 to June 2013
- (2013) Heesun Chung et al. Forensic Toxicology
- Two new synthetic cannabinoids, AM-2201 benzimidazole analog (FUBIMINA) and (4-methylpiperazin-1-yl)(1-pentyl-1H-indol-3-yl)methanone (MEPIRAPIM), and three phenethylamine derivatives, 25H-NBOMe 3,4,5-trimethoxybenzyl analog, 25B-NBOMe, and 2C-N-NBOMe, identified in illegal products
- (2013) Nahoko Uchiyama et al. Forensic Toxicology
- SPME–GC–MS analysis of α-pyrrolidinovaleorophenone in blood in a fatal poisoning case
- (2013) Takeshi Saito et al. Forensic Toxicology
- Presence and composition of cathinone derivatives in drug samples taken from a Drug Test Service in Spain (2010-2012)
- (2013) Fernando Caudevilla-Gálligo et al. HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL
- Driving under the influence of synthetic cannabinoids (“Spice”): a case series
- (2013) Frank Musshoff et al. INTERNATIONAL JOURNAL OF LEGAL MEDICINE
- Blood Synthetic Cannabinoid Concentrations in Cases of Suspected Impaired Driving
- (2013) J. K. Yeakel et al. JOURNAL OF ANALYTICAL TOXICOLOGY
- The Stability of Four Designer Drugs: MDPV, Mephedrone, BZP and TFMPP in Three Biological Matrices under Various Storage Conditions
- (2013) R. D. Johnson et al. JOURNAL OF ANALYTICAL TOXICOLOGY
- Validation of a Novel Immunoassay for the Detection of Synthetic Cannabinoids and Metabolites in Urine Specimens
- (2013) A. Arntson et al. JOURNAL OF ANALYTICAL TOXICOLOGY
- Mephedrone (Methylmethcathinone) in Toxicology Casework: A Northern Ireland Perspective
- (2013) S. H. Cosbey et al. JOURNAL OF ANALYTICAL TOXICOLOGY
- Postmortem Tissue Distribution of MDPV Following Lethal Intoxication by "Bath Salts"
- (2013) J. F. Wyman et al. JOURNAL OF ANALYTICAL TOXICOLOGY
- Analysis of Synthetic Cathinones Commonly Found in Bath Salts in Human Performance and Postmortem Toxicology: Method Development, Drug Distribution and Interpretation of Results
- (2013) L. J. Marinetti et al. JOURNAL OF ANALYTICAL TOXICOLOGY
- Analysis of MDPV in Blood--Determination and Interpretation
- (2013) P. Adamowicz et al. JOURNAL OF ANALYTICAL TOXICOLOGY
- K2 Toxicity: Fatal Case of Psychiatric Complications Following AM2201 Exposure
- (2013) Amy L. Patton et al. JOURNAL OF FORENSIC SCIENCES
- Methylenedioxypyrovalerone (“Bath Salts”),Related Death: Case Report and Review of the Literature,
- (2013) Kilak Kesha et al. JOURNAL OF FORENSIC SCIENCES
- Deaths Involving Methylenedioxypyrovalerone (MDPV) in Upper East Tennessee
- (2013) Trista H. Wright et al. JOURNAL OF FORENSIC SCIENCES
- Quadrupole-time-of-flight mass spectrometry screening for synthetic cannabinoids in herbal blends
- (2013) María Ibáñez et al. JOURNAL OF MASS SPECTROMETRY
- Identification of substituted cathinones: 3,4-Methylenedioxy derivatives by high performance liquid chromatography–quadrupole time of flight mass spectrometry
- (2013) Emilia Fornal JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Acute toxicity due to the confirmed consumption of synthetic cannabinoids: clinical and laboratory findings
- (2012) Maren Hermanns-Clausen et al. ADDICTION
- Simultaneous analysis of synthetic cannabinoids in the materials seized during drug trafficking using GC-MS
- (2012) Hyeyoung Choi et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Determination of 32 cathinone derivatives and other designer drugs in serum by comprehensive LC-QQQ-MS/MS analysis
- (2012) Madeleine J. Swortwood et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Analysis of 30 synthetic cannabinoids in oral fluid using liquid chromatography-electrospray ionization tandem mass spectrometry
- (2012) Stefan Kneisel et al. Drug Testing and Analysis
- Prevalence of new psychoactive substances: A retrospective study in hair
- (2012) Kristina Yasmin Rust et al. Drug Testing and Analysis
- Ring positional differentiation of isomeric N-alkylated fluorocathinones by gas chromatography/tandem mass spectrometry
- (2012) Folker Westphal et al. FORENSIC SCIENCE INTERNATIONAL
- Synthetic cannabinoids in “spice-like” herbal blends: First appearance of JWH-307 and recurrence of JWH-018 on the German market
- (2012) Ludger Ernst et al. FORENSIC SCIENCE INTERNATIONAL
- “Legal highs”—Toxicity in the clinical and medico-legal aspect as exemplified by suicide with bk-MBDB administration
- (2012) Sebastian Rojek et al. FORENSIC SCIENCE INTERNATIONAL
- Detection of buphedrone in biological and non-biological material – Two case reports
- (2012) Dariusz Zuba et al. FORENSIC SCIENCE INTERNATIONAL
- Urinary excretion and metabolism of the newly encountered designer drug 3,4-dimethylmethcathinone in humans
- (2012) N. Shima et al. Forensic Toxicology
- Changes in the prevalence of synthetic cannabinoids and cathinone derivatives in Japan until early 2012
- (2012) Ruri Kikura-Hanajiri et al. Forensic Toxicology
- Identification of two new-type synthetic cannabinoids, N-(1-adamantyl)-1-pentyl-1H-indole-3-carboxamide (APICA) and N-(1-adamantyl)-1-pentyl-1H-indazole-3-carboxamide (APINACA), and detection of five synthetic cannabinoids, AM-1220, AM-2233, AM-1241, CB-13 (CRA-13), and AM-1248, as designer drugs in illegal products
- (2012) Nahoko Uchiyama et al. Forensic Toxicology
- New cannabimimetic indazole derivatives, N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-pentyl-1H-indazole-3-carboxamide (AB-PINACA) and N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(4-fluorobenzyl)-1H-indazole-3-carboxamide (AB-FUBINACA) identified as designer drugs in illegal products
- (2012) Nahoko Uchiyama et al. Forensic Toxicology
- Use of SPME-HS-GC-MS for the Analysis of Herbal Products Containing Synthetic Cannabinoids
- (2012) A. O. Cox et al. JOURNAL OF ANALYTICAL TOXICOLOGY
- Distribution of Methylone in Four Postmortem Cases
- (2012) B. M. Cawrse et al. JOURNAL OF ANALYTICAL TOXICOLOGY
- Fatal Mephedrone Intoxication—A Case Report
- (2012) Piotr Adamowicz et al. JOURNAL OF ANALYTICAL TOXICOLOGY
- Detection of JWH-018 and JWH-073 by UPLC-MS-MS in Postmortem Whole Blood Casework
- (2012) K. G. Shanks et al. JOURNAL OF ANALYTICAL TOXICOLOGY
- Three Fatal Intoxications Due to Methylone
- (2012) J. M. Pearson et al. JOURNAL OF ANALYTICAL TOXICOLOGY
- New challenges and innovation in forensic toxicology: Focus on the “New Psychoactive Substances”
- (2012) Donata Favretto et al. JOURNAL OF CHROMATOGRAPHY A
- Determination of 22 synthetic cannabinoids in human hair by liquid chromatography–tandem mass spectrometry
- (2012) Melanie Hutter et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- LC–MS/MS method for the quantitation of metabolites of eight commonly-used synthetic cannabinoids in human urine – An Australian perspective
- (2012) Andrew D. de Jager et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- High-throughput bioanalytical method for analysis of synthetic cannabinoid metabolites in urine using salting-out sample preparation and LC–MS/MS
- (2012) Enrique G. Yanes et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- Identification of Synthetic Cannabinoids in Herbal Incense Blends in the United States
- (2012) Barry K. Logan et al. JOURNAL OF FORENSIC SCIENCES
- Identification and structural characterization of the synthetic cannabinoid 3-(1-adamantoyl)-1-pentylindole as an additive in ‘herbal incense’
- (2012) Stefan Kneisel et al. JOURNAL OF MASS SPECTROMETRY
- Identification of the major urinary metabolites in man of seven synthetic cannabinoids of the aminoalkylindole type present as adulterants in ‘herbal mixtures’ using LC-MS/MS techniques
- (2012) M. Hutter et al. JOURNAL OF MASS SPECTROMETRY
- Analysis of 30 synthetic cannabinoids in serum by liquid chromatography-electrospray ionization tandem mass spectrometry after liquid-liquid extraction
- (2012) Stefan Kneisel et al. JOURNAL OF MASS SPECTROMETRY
- Identification of naphthoylindoles acting on cannabinoid receptors based on their fragmentation patterns under ESI-QTOFMS
- (2012) Karolina Sekuła et al. JOURNAL OF MASS SPECTROMETRY
- Mephedrone (4-methylmethcathinone): What is new in our understanding of its use and toxicity
- (2012) David M. Wood et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Intoxication Delirium following Use of Synthetic Cathinone Derivatives
- (2012) Thomas M. Penders et al. AMERICAN JOURNAL OF DRUG AND ALCOHOL ABUSE
- A new designer drug: Methylone related death
- (2012) Katalin Kovács et al. ORVOSI HETILAP
- Quantitative Measurement of JWH-018 and JWH-073 Metabolites Excreted in Human Urine
- (2011) Cindy L. Moran et al. ANALYTICAL CHEMISTRY
- Solid-Phase Extraction and Quantitative Measurement of Omega and Omega-1 Metabolites of JWH-018 and JWH-073 in Human Urine
- (2011) Krishna C. Chimalakonda et al. ANALYTICAL CHEMISTRY
- Clinical experience with and analytical confirmation of “bath salts” and “legal highs” (synthetic cathinones) in the United States
- (2011) Henry A. Spiller et al. CLINICAL TOXICOLOGY
- The emergence and analysis of synthetic cannabinoids
- (2011) Simon Hudson et al. Drug Testing and Analysis
- Identification and characterization of the new designer drug 4′-methylethcathinone (4-MEC) and elaboration of a novel liquid chromatography–tandem mass spectrometry (LC–MS/MS) screening method for seven different methcathinone analogs
- (2011) Péter Jankovics et al. FORENSIC SCIENCE INTERNATIONAL
- A case of extreme agitation and death after the use of mephedrone in The Netherlands
- (2011) Klaas J. Lusthof et al. FORENSIC SCIENCE INTERNATIONAL
- New designer drug of abuse: 3,4-Methylenedioxypyrovalerone (MDPV). Findings from apprehended drivers in Finland
- (2011) Pirkko Kriikku et al. FORENSIC SCIENCE INTERNATIONAL
- Development and Validation of a Liquid Chromatography-Tandem Mass Spectrometry Method for the Identification and Quantification of JWH-018, JWH-073, JWH-019, and JWH-250 in Human Whole Blood
- (2011) S. L. Kacinko et al. JOURNAL OF ANALYTICAL TOXICOLOGY
- Mephedrone (4-Methylmethcathinone)-Related Deaths
- (2011) P. D. Maskell et al. JOURNAL OF ANALYTICAL TOXICOLOGY
- Determination of cathinones and related ephedrines in forensic whole-blood samples by liquid-chromatography–electrospray tandem mass spectrometry
- (2011) Lambert K. Sørensen JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- Fragmentation pathways of drugs of abuse and their metabolites based on QTOF MS/MS and MSE accurate-mass spectra
- (2011) Lubertus Bijlsma et al. JOURNAL OF MASS SPECTROMETRY
- Development and validation of a liquid chromatography-tandem mass spectrometry method for the quantitation of synthetic cannabinoids of the aminoalkylindole type and methanandamide in serum and its application to forensic samples
- (2011) Sebastian Dresen et al. JOURNAL OF MASS SPECTROMETRY
- Identification of cathinones and other active components of ‘legal highs’ by mass spectrometric methods
- (2011) Dariusz Zuba TRAC-TRENDS IN ANALYTICAL CHEMISTRY
- Analyses of second-generation ‘legal highs’ in the UK: Initial findings
- (2010) Simon D. Brandt et al. Drug Testing and Analysis
- Analysis of NRG ‘legal highs’ in the UK: identification and formation of novel cathinones
- (2010) Simon D. Brandt et al. Drug Testing and Analysis
- The detection of mephedrone (4-methylmethcathinone) in 4 fatalities in Scotland
- (2010) Hazel Torrance et al. FORENSIC SCIENCE INTERNATIONAL
- Sensitive and rapid quantification of the cannabinoid receptor agonist naphthalen-1-yl-(1-pentylindol-3-yl)methanone (JWH-018) in human serum by liquid chromatography–tandem mass spectrometry
- (2010) Jörg Teske et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- Studies on the metabolism of the α-pyrrolidinophenone designer drug methylenedioxy-pyrovalerone (MDPV) in rat and human urine and human liver microsomes using GC-MS and LC-high-resolution MS and its detectability in urine by GC-MS
- (2010) Markus R. Meyer et al. JOURNAL OF MASS SPECTROMETRY
- Toxicological determination and in vitro metabolism of the designer drug methylenedioxypyrovalerone (MPDV) by gas chromatography/mass spectrometry and liquid chromatography/quadrupole time-of-flight mass spectrometry
- (2010) Sabina Strano-Rossi et al. RAPID COMMUNICATIONS IN MASS SPECTROMETRY
- New designer drug α‐pyrrolidinovalerophenone (PVP): studies on its metabolism and toxicological detection in rat urine using gas chromatographic/mass spectrometric techniques
- (2009) Christoph Sauer et al. JOURNAL OF MASS SPECTROMETRY
- ‘Spice’ and other herbal blends: harmless incense or cannabinoid designer drugs?
- (2009) Volker Auwärter et al. JOURNAL OF MASS SPECTROMETRY
- Analytical Data of Designated Substances (Shitei-Yakubutsu) Controlled by the Pharmaceutical Affairs Law in Japan, Part II: Color Test and TLC
- (2008) Nahoko UCHIYAMA et al. YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now