Review
Biotechnology & Applied Microbiology
Sushma Mishra, Pramod Kumar Sahu, Vishad Agarwal, Namrata Singh
Summary: Plant secondary metabolites have potential applications in various industries, but their direct isolation from plants may lead to over-harvesting and loss of biodiversity. Endophytic microbes have the ability to produce metabolites similar to those of their host plants, providing a sustainable and commercially valuable resource.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Rongsheng Li, Kou Wang, Dong Wang, Liping Xu, Yusong Shi, Zhubo Dai, Xueli Zhang
Summary: This study successfully increased the production of citronellol, geraniol, and nerol by reconstructing the biosynthetic pathways in yeast, leading to the synthesis of synthetic rose oil. This synthetic biology platform serves as a sustainable microbial source for important PVTs production.
Review
Biochemistry & Molecular Biology
Tong Wu, Sandra M. Kerbler, Alisdair R. Fernie, Youjun Zhang
Summary: Synthetic biology in plants has attracted increasing attention, and plant cells may be a promising alternative for the production of high-value metabolites. Commercial plant suspension cell cultures have been successfully used to produce valuable metabolites in a safe and cost-effective manner, but the variety of metabolites biosynthesized using plant platforms is currently limited.
PLANT COMMUNICATIONS
(2021)
Article
Green & Sustainable Science & Technology
Michael Eaton, Timothy Shelford, Melissa Cole, Neil Mattson
Summary: Plant factories, with multi-layer production in opaque warehouses, have potential benefits but also key impediments, such as energy consumption. This study models energy and water use in plant factories growing lettuce in five U.S. locations, using different energy conservation measures. The results show that locating plant factories in areas with a cleaner grid and employing these measures can reduce energy consumption, but tradeoffs between water, energy, and supplementary carbon dioxide need to be considered in design.
JOURNAL OF CLEANER PRODUCTION
(2023)
Article
Biotechnology & Applied Microbiology
Jiachen Sun, Wentao Sun, Genlin Zhang, Bo Lv, Chun Li
Summary: Plant flavonoids are secondary metabolites with various physiological and pharmacological activities. Current production methods from plants or chemicals do not meet the requirements of green and sustainable development. Microbial synthesis of flavonoids has shown potential for large-scale production, but challenges such as metabolic flux imbalance and conflict between cell growth and production hinder commercialization of microbial cell factories. Strategies discussed in this article, combined with protein structure prediction, de novo protein design, artificial intelligence, biocatalytic retrosynthesis, and intelligent stress resistance, provide insights for efficient production of plant flavonoids and other natural products in microbial cell factories.
METABOLIC ENGINEERING
(2022)
Review
Biotechnology & Applied Microbiology
J. W. Huebbers, J. F. Buyel
Summary: The biopharmaceutical market is driven by recombinant proteins, mainly for vaccines and antibodies. Plant molecular farming as an alternative production method offers scalability and cost efficiency in upstream processes. However, lack of standardized process equipment has hindered approvals for pharmaceutical proteins from whole plants.
BIOTECHNOLOGY ADVANCES
(2021)
Review
Agricultural Engineering
Jina Son, Kei-Anne Baritugo, Seo Hyun Lim, Hye Jin Lim, Seona Jeong, Ji Yeon Lee, Jong-il Choi, Jeong Chan Joo, Jeong-Geol Na, Si Jae Park
Summary: Currently, linear petroleum-based industries are causing depletion of finite natural resources and accumulation of non-biodegradable and hazardous wastes, highlighting the need for ecofriendly and sustainable solutions. Utilizing agro-industrial wastes as substrates can lead to the production of target value-added chemicals like organic acids, with advancements in metabolic engineering strategies and techniques enhancing their production. Further development and future perspectives in utilizing waste-based biorefineries for organic acid production from various industries have been discussed to showcase their importance.
BIORESOURCE TECHNOLOGY
(2022)
Article
Energy & Fuels
Rupsha Bhattacharyya, Krishna Kumar Singh, Ravi Bhushan Grover, Kalyan Bhanja
Summary: Hydrogen production through water splitting using nuclear electricity is considered a promising option for establishing a low-carbon economy, but currently, there is greater focus on renewable energy sources due to high upfront capital investment and skewed perception of risks associated with nuclear power.
INTERNATIONAL JOURNAL OF ENERGY RESEARCH
(2022)
Article
Green & Sustainable Science & Technology
Heino Pesch, Louis Louw
Summary: This paper explores the integration of external industries with plant factories by defining an open-loop system boundary. A decision-support process using a mixed-indicator assessment method and fuzzy TOPSIS was developed to account for uncertainties. The fuzzy TOPSIS ranking provided a clearer hierarchy of optimal scenarios compared to using indicator rankings.
Article
Energy & Fuels
Nilofar Gerami, Ahmad Ghasemi, Amir Lotfi, Lisa Gakenia Kaigutha, Mousa Marzband
Summary: This paper presents a new model of energy consumption and evaluates its performance through three case studies. The research findings indicate that implementing demand response programs and involving industrial factories in energy markets can increase revenue.
SUSTAINABLE ENERGY GRIDS & NETWORKS
(2021)
Review
Biotechnology & Applied Microbiology
Yanyan Wang, Linxia Liu, Zhaoxia Jin, Dawei Zhang
Summary: Vitamins are essential for maintaining normal metabolism and health, with wide applications in various industries. Using microbial cell factories for vitamin production is both environmentally friendly and economically sustainable, covering water-soluble and fat-soluble vitamins.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Agricultural Engineering
Aravind Madhavan, K. B. Arun, Raveendran Sindhu, Anju Alphonsa Jose, Arivalagan Pugazhendhi, Parameswaran Binod, Ranjna Sirohi, R. Reshmy, Mukesh Kumar Awasthi
Summary: Filamentous fungi have versatile capabilities for synthesizing valuable bio compounds such as enzymes, organic acids, and small molecule secondary metabolites. Using basic biochemical methods, filamentous fungi can convert lignocellulose into fermentable sugars and other biochemical products.
BIORESOURCE TECHNOLOGY
(2022)
Article
Thermodynamics
Till Weidner, Aidong Yang, Michael W. Hamm
Summary: The trend towards localizing food production is driving the development of controlled-environment agriculture, particularly indoor vertical farming, to ensure year-round supply of healthy food. However, high energy consumption remains a major concern that needs to be addressed to ensure environmental sustainability.
ENERGY CONVERSION AND MANAGEMENT
(2021)
Article
Agriculture, Multidisciplinary
Chunyang Cao, Haiyan Zhang, Xuan Cao, Sijia Kong, Beiwei Zhu, Xinping Lin, Yongjin J. Zhou
Summary: Engineering microorganisms to synthesize isoprenoids is an efficient approach to increase their concentration. In this study, three types of isoprenoid pathways were constructed and optimized in yeast peroxisomes to produce the sesquiterpene (+)-valencene. The Haloarchaea-type MVA pathway was found to be more effective, and a production of 869 mg/L (+)-valencene was achieved. This work expands isoprenoid synthesis in eukaryotes and provides a more efficient pathway for isoprenoid production.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Review
Multidisciplinary Sciences
Xiao Han, Jiongqin Liu, Sen Tian, Fei Tao, Ping Xu
Summary: This article discusses the feasibility and technical challenges of using biodegradable plastics as green substitutes for traditional plastics, introduces the basic properties of the main biodegradable plastics on the market, and proposes strategies to advance their commercial production through metabolic engineering and synthetic biology. It also analyzes the main challenges facing the current development of bio-based biodegradable plastic biosynthesis technology.
Article
Plant Sciences
Juliana Almeida, Mariana da Silva Azevedo, Livia Spicher, Gaetan Glauser, Katharina vom Dorp, Luzia Guyer, Andrea del Valle Carranza, Ramon Asis, Amanda Pereira de Souza, Marcos Buckeridge, Diego Demarco, Cecile Bres, Christophe Rothan, Lazaro Eustaquio Pereira Peres, Stefan Hoertensteiner, Felix Kessler, Peter Doermann, Fernando Carrari, Magdalena Rossi
JOURNAL OF EXPERIMENTAL BOTANY
(2016)
Article
Biochemistry & Molecular Biology
Juliana Almeida, Ramon Asis, Virginia Noel Molineri, Ivan Sestari, Bruno Silvestre Lira, Fernando Carrari, Lazar Eustaquio Pereira Peres, Magdalena Rossi
Article
Multidisciplinary Sciences
Paula Elbl, Bruno V. Navarro, Leandro F. de Oliveira, Juliana Almeida, C. Mosini, Andre L. W. dos Santos, Magdalena Rossi, Eny I. S. Floh
Article
Plant Sciences
Bruno Silvestre Lira, Daniele Rosado, Juliana Almeida, Amanda Pereira de Souza, Marcos Silveira Buckeridge, Eduardo Purgatto, Luzia Guyer, Stefan Hoertensteiner, Luciano Freschi, Magdalena Rossi
PLANT AND CELL PHYSIOLOGY
(2016)
Article
Plant Sciences
Livia Spicher, Juliana Almeida, Katharina Gutbrod, Rosa Pipitone, Peter Doermann, Gaetan Glauser, Magdalena Rossi, Felix Kessler
JOURNAL OF EXPERIMENTAL BOTANY
(2017)
Article
Genetics & Heredity
Bruno Silvestre Lira, Nathalia de Setta, Daniele Rosado, Juliana Almeida, Luciano Freschi, Magdalena Rossi
Article
Plant Sciences
Juliana Almeida, Leandro Quadrana, Ramon Asis, Nathalia Setta, Fabiana de Godoy, Luisa Bermudez, Santiago N. Otaiza, Junia V. Correa da Silva, Alisdair R. Fernie, Fernando Carrari, Magdalena Rossi
JOURNAL OF EXPERIMENTAL BOTANY
(2011)
Article
Plant Sciences
Fabiana de Godoy, Luisa Bermudez, Bruno Silvestre Lira, Amanda Pereira de Souza, Paula Elbl, Diego Demarco, Saleh Alseekh, Marina Insani, Marcos Buckeridge, Juliana Almeida, Gabriela Grigioni, Alisdair Robert Fernie, Fernando Carrari, Magdalena Rossi
JOURNAL OF EXPERIMENTAL BOTANY
(2013)
Article
Zoology
Nadia de Moraes-Barros, Juliana A. B. Silva, Joao Stenghel Morgante
JOURNAL OF MAMMALOGY
(2011)
Article
Plant Sciences
Luisa Bermudez, Talia del Pozo, Bruno Silvestre Lira, Fabiana de Godoy, Irene Boos, Cecilia Romano, Viola Previtali, Juliana Almeida, Claire Brehelin, Ramon Asis, Leandro Quadrana, Diego Demarco, Saleh Alseekh, Rigel Salinas Gamboa, Laura Perez-Flores, Pia Guadalupe Dominguez, Christophe Rothan, Alisdair Robert Fernie, Mauricio Gonzalez, Achim Stocker, Andreas Hemmerle, Mads Hartving Clausen, Fernando Carrari, Magdalena Rossi
PLANT AND CELL PHYSIOLOGY
(2018)
Article
Plant Sciences
Luisa Bermudez, Fabiana de Godoy, Pierre Baldet, Diego Demarco, Sonia Osorio, Leandro Quadrana, Juliana Almeida, Ramon Asis, Yves Gibon, Alisdair R. Fernie, Magdalena Rossi, Fernando Carrari
Article
Biochemistry & Molecular Biology
Leandro Quadrana, Juliana Almeida, Santiago N. Otaiza, Tomas Duffy, Junia V. Correa da Silva, Fabiana de Godoy, Ramon Asis, Luisa Bermudez, Alisdair R. Fernie, Fernando Carrari, Magdalena Rossi
PLANT MOLECULAR BIOLOGY
(2013)
Article
Multidisciplinary Sciences
Leandro Quadrana, Juliana Almeida, Ramon Asis, Tomas Duffy, Pia Guadalupe Dominguez, Luisa Bermudez, Gabriela Conti, Junia V. Correa da Silva, Iris E. Peralta, Vincent Colot, Sebastian Asurmendi, Alisdair R. Fernie, Magdalena Rossi, Fernando Carrari
NATURE COMMUNICATIONS
(2014)
Article
Plant Sciences
Juliana Almeida, Laura Perez-Fons, Paul D. Fraser
Summary: High temperatures can negatively influence plant growth and development, including the quality traits of fruits. Research on tomato fruit exposed to heat stress revealed changes in nutritional attributes and disruptions in carotenogenesis and plastidial isoprenoid compounds. Metabolite profiling showed limited effects on primary metabolism but lipid remodelling, sucrose accumulation, and membrane lipid saturation changes were evident.
PLANT CELL AND ENVIRONMENT
(2021)
Review
Biochemical Research Methods
Pei-Ru Chen, Peng-Fei Xia
Summary: Carbon dioxide plays a crucial role in mitigating global climate change and supporting life on Earth. Synthetic biology and metabolic engineering offer a promising approach to enhance CO2 fixation by combining the advantages of autotrophic and heterotrophic organisms. This article reviews the current progress in constructing synthetic CO2 fixation pathways, discusses the underlying design principles and challenges, and provides insights into the future of carbon recycling through engineered synthetic carbon fixation pathways.
CURRENT OPINION IN BIOTECHNOLOGY
(2024)