Laboratory diagnosis of Lyme borreliosis: Current state of the art and future perspectives

To test or not to test? Laboratory support for the diagnosis of Lyme borreliosis: a position paper of ESGBOR, the ESCMID study group for Lyme borreliosis

(2018) R.B. Dessau et al.   CLINICAL MICROBIOLOGY AND INFECTION

Published data do not support the notion that Borrelia valaisiana is human pathogenic

(2017) Gabriele Margos et al.   INFECTION

Diagnosing Borreliosis

(2017) Sally J. Cutler et al.   VECTOR-BORNE AND ZOONOTIC DISEASES

The diagnostic accuracy of serological tests for Lyme borreliosis in Europe: a systematic review and meta-analysis

(2016) M. M. G. Leeflang et al.   BMC INFECTIOUS DISEASES

Progress in the molecular diagnosis of Lyme disease

(2016) Eva Ružić-Sabljić et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Borrelia bissettiae sp. nov. and Borrelia californiensis sp. nov. prevail in diverse enzootic transmission cycles

(2016) Gabriele Margos et al.   INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY

Borrelia mayonii sp. nov., a member of the Borrelia burgdorferi sensu lato complex, detected in patients and ticks in the upper midwestern United States

(2016) Bobbi S. Pritt et al.   INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY

A divergent spirochete strain isolated from a resident of the southeastern United States was identified by multilocus sequence typing as Borrelia bissettii.

(2016) Maryna Golovchenko et al.   Parasites & Vectors

Concordance of four commercial enzyme immunoassay and three immunoblot formats for the detection of Lyme borreliosis antibodies in human serum: the two-tier approach remains

(2016) David J. Dickeson et al.   PATHOLOGY

A tribute to Dr. Willy Burgdorfer, Medical Entomologist Extraordinaire

(2016) L. Gern et al.   Ticks and Tick-Borne Diseases

Validate or falsify: Lessons learned from a microscopy method claimed to be useful for detectingBorreliaandBabesiaorganisms in human blood

(2016) Audun Aase et al.   Infectious Diseases

Lyme borreliosis

(2016) Allen C. Steere et al.   Nature Reviews Disease Primers

Comparison of Growth of Borrelia afzelii, Borrelia garinii, and Borrelia burgdorferi Sensu Stricto at Five Different Temperatures

(2016) Gorana Veinović et al.   PLoS One

Prevalence of Rickettsia spp. in Ticks and Serological and Clinical Outcomes in Tick-Bitten Individuals in Sweden and on the Åland Islands

(2016) Anders Lindblom et al.   PLoS One

Whole genome capture of vector-borne pathogens from mixed DNA samples: a case study of Borrelia burgdorferi

(2015) Giovanna Carpi et al.   BMC GENOMICS

Alternatives to Serologic Testing for Diagnosis of Lyme Disease

(2015) Kevin Alby et al.   CLINICS IN LABORATORY MEDICINE

Multiplex assay (Mikrogen recomBead) for detection of serum IgG and IgM antibodies to 13 recombinant antigens of Borrelia burgdorferi sensu lato in patients with neuroborreliosis: the more the better?

(2015) R. B. Dessau et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Application of Nanotrap technology for high sensitivity measurement of urinary outer surface protein A carboxyl-terminus domain in early stage Lyme borreliosis

(2015) Ruben Magni et al.   Journal of Translational Medicine

Editorial Commentary: Xenodiagnosis for Posttreatment Lyme Disease Syndrome: Resolving the Conundrum or Adding to It?

(2014) L. K. Bockenstedt et al.   CLINICAL INFECTIOUS DISEASES

Xenodiagnosis to Detect Borrelia burgdorferi Infection: A First-in-Human Study

(2014) Adriana Marques et al.   CLINICAL INFECTIOUS DISEASES

The lymphocyte transformation test for the diagnosis of Lyme borreliosis has currently not been shown to be clinically useful

(2014) R.B. Dessau et al.   CLINICAL MICROBIOLOGY AND INFECTION

Evaluation of two commercially available rapid diagnostic tests for Lyme borreliosis

(2014) P. W. Smit et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Borrelia burgdorferi sensu lato serology in the Netherlands: guidelines versus daily practice

(2014) J. Coumou et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Is there a place for xenodiagnosis in the clinic?

(2014) Sam R Telford et al.   Expert Review of Anti-Infective Therapy

Selective Whole Genome Amplification for Resequencing Target Microbial Species from Complex Natural Samples

(2014) A. R. Leichty et al.   GENETICS

CXCL13 and neopterin concentrations in cerebrospinal fluid of patients with Lyme neuroborreliosis and other diseases that cause neuroinflammation

(2014) Jukka Hytönen et al.   Journal of Neuroinflammation

CXCL13 plus interleukin 10 is highly specific for the diagnosis of CNS lymphoma

(2013) J. L. Rubenstein et al.   BLOOD

Editorial Commentary: Better Laboratory Testing for Lyme Disease: No More Western Blot

(2013) R. T. Schoen   CLINICAL INFECTIOUS DISEASES

A Systematic Review of Borrelia burgdorferi Morphologic Variants Does Not Support a Role in Chronic Lyme Disease

(2013) P. M. Lantos et al.   CLINICAL INFECTIOUS DISEASES

Performance of United States Serologic Assays in the Diagnosis of Lyme Borreliosis Acquired in Europe

(2013) J. A. Branda et al.   CLINICAL INFECTIOUS DISEASES

Comparison of isolation rate of Borrelia burgdorferi sensu lato in two different culture media, MKP and BSK-H

(2013) E. Ružić-Sabljić et al.   CLINICAL MICROBIOLOGY AND INFECTION

Achieving molecular diagnostics for Lyme disease

(2013) Mark W Eshoo et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

DNA persistence after treatment of Lyme borreliosis

(2013) D. Pícha et al.   FOLIA MICROBIOLOGICA

Understanding Barriers to Borrelia burgdorferi Dissemination during Infection Using Massively Parallel Sequencing

(2013) Erin B. Troy et al.   INFECTION AND IMMUNITY

Improved Culture Conditions for the Growth and Detection of Borrelia from Human Serum

(2013) Eva Sapi et al.   International Journal of Medical Sciences

Assessment of New Culture Method for Detection of Borrelia Species from Serum of Lyme Disease Patients

(2013) B. J. B. Johnson et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Diagnostic accuracy and comparison of two assays for Borrelia-specific IgG and IgM antibodies: proposals for statistical evaluation methods, cut-off values and standardization

(2013) R. B. Dessau   JOURNAL OF MEDICAL MICROBIOLOGY

Diagnosis of neuroborreliosis – Improved knowledge base for qualified antibody analysis and cerebrospinal fluid data pattern related interpretations

(2013) Hansotto Reiber et al.   NEUROLOGY PSYCHIATRY AND BRAIN RESEARCH

Spirochete antigens persist near cartilage after murine Lyme borreliosis therapy

(2012) Linda K. Bockenstedt et al.   JOURNAL OF CLINICAL INVESTIGATION

Detection of Borrelia burgdorferi Nucleic Acids after Antibiotic Treatment Does Not Confirm Viability

(2012) Radha Iyer et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Identification of Endosymbionts in Ticks by Broad-Range Polymerase Chain Reaction and Electrospray Ionization Mass Spectrometry

(2012) Megan A. Rounds et al.   JOURNAL OF MEDICAL ENTOMOLOGY

Genome Stability of Lyme Disease Spirochetes: Comparative Genomics of Borrelia burgdorferi Plasmids

(2012) Sherwood R. Casjens et al.   PLoS One

Direct Molecular Detection and Genotyping of Borrelia burgdorferi from Whole Blood of Patients with Early Lyme Disease

(2012) Mark W. Eshoo et al.   PLoS One

Can ELISPOT Be Applied to A Clinical Setting as A Diagnostic Utility for Neuroborreliosis?

(2012) Marika Nordberg et al.   Cells

Evaluating Frequency, Diagnostic Quality, and Cost of Lyme Borreliosis Testing in Germany: A Retrospective Model Analysis

(2011) I. Müller et al.   Clinical & Developmental Immunology

Multiplex Immunoassay for Lyme Disease Using VlsE1-IgG and pepC10-IgM Antibodies: Improving Test Performance through Bioinformatics

(2011) Richard B. Porwancher et al.   Clinical and Vaccine Immunology

Two-Tiered Antibody Testing for Lyme Disease With Use of 2 Enzyme Immunoassays, a Whole-Cell Sonicate Enzyme Immunoassay Followed by a VlsE C6 Peptide Enzyme Immunoassay

(2011) J. A. Branda et al.   CLINICAL INFECTIOUS DISEASES

The expanding Lyme Borrelia complex—clinical significance of genomic species?

(2011) G. Stanek et al.   CLINICAL MICROBIOLOGY AND INFECTION

High frequency of false positive IgM immunoblots for Borrelia burgdorferi in Clinical Practice

(2011) V. Seriburi et al.   CLINICAL MICROBIOLOGY AND INFECTION

Large differences between test strategies for the detection of anti-Borrelia antibodies are revealed by comparing eight ELISAs and five immunoblots

(2011) C. W. Ang et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Population genetics, taxonomy, phylogeny and evolution of Borrelia burgdorferi sensu lato

(2011) Gabriele Margos et al.   INFECTION GENETICS AND EVOLUTION

Improving the Yield of Blood Cultures from Patients with Early Lyme Disease

(2011) Dionysios Liveris et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Cerebrospinal fluid findings in adults with acute Lyme neuroborreliosis

(2011) Marija Djukic et al.   JOURNAL OF NEUROLOGY

Lyme borreliosis

(2011) Gerold Stanek et al.   LANCET

A prospective study on the role of CXCL13 in Lyme neuroborreliosis

(2011) C. Schmidt et al.   NEUROLOGY

Simultaneous use of serum IgG and IgM for risk scoring of suspected early Lyme borreliosis: graphical and bivariate analyses

(2010) RAM B. DESSAU et al.   APMIS

Utilization of serology for the diagnosis of suspected Lyme borreliosis in Denmark: Survey of patients seen in general practice

(2010) Ram B Dessau et al.   BMC INFECTIOUS DISEASES

Lyme borreliosis: Clinical case definitions for diagnosis and management in Europe

(2010) G. Stanek et al.   CLINICAL MICROBIOLOGY AND INFECTION

New technology for rapid molecular diagnosis of bloodstream infections

(2010) David J Ecker et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Blood Cultures for Patients with Extracutaneous Manifestations of Lyme Disease in the United States

(2009) John Nowakowski et al.   CLINICAL INFECTIOUS DISEASES

EFNS guidelines on the diagnosis and management of European Lyme neuroborreliosis

(2009) Å. Mygland et al.   EUROPEAN JOURNAL OF NEUROLOGY

The chemokine CXCL13 is a key regulator of B cell recruitment to the cerebrospinal fluid in acute Lyme neuroborreliosis

(2009) Tobias A Rupprecht et al.   Journal of Neuroinflammation

Borrelia burgdorferi, a great chameleon: know it to recognize it!

(2009) Iolanda Santino et al.   NEUROLOGICAL SCIENCES

Lyme Disease: Laboratory Issues

(2008) Maria E. Aguero-Rosenfeld   INFECTIOUS DISEASE CLINICS OF NORTH AMERICA

Borrelia burgdorferiGenotype Predicts the Capacity for Hematogenous Dissemination during Early Lyme Disease

(2008) Gary P. Wormser et al.   JOURNAL OF INFECTIOUS DISEASES

CSF B – lymphocyte chemoattractant (CXCL13) in the early diagnosis of acute Lyme neuroborreliosis

(2008) U. Ljøstad et al.   JOURNAL OF NEUROLOGY

Characterization of Borrelia burgdorferi sensu lato isolates by pulsed-field gel electrophoresis after MluI restriction of genomic DNA

(2008) Eva Ružić-Sabljić et al.   RESEARCH IN MICROBIOLOGY

Epidemiological aspects and molecular characterization of Borrelia burgdorferi s.l. from southern Germany with special respect to the new species Borrelia spielmanii sp. nov.

(2007) Volker Fingerle et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY