Article
Peripheral Vascular Disease
Julieta S. Del Mauro, Paula D. Prince, Yanina Santander Plantamura, Miguel A. Allo, Luciano Parola, Nahuel Fernandez Machulsky, Marcela A. Moretton, Eliana P. Bin, German E. Gonzalez, Facundo M. Bertera, Andrea Carranza, Gabriela Berg, Carlos A. Taira, Martin Donato, Diego A. Chiappetta, Ariel H. Polizio, Christian Hocht
Summary: By comparing the effects of nebivolol and atenolol on hypertensive rats, it was found that nebivolol was more effective in reducing central systolic blood pressure and blood pressure variability, as well as providing greater protection against target organ damage.
HYPERTENSION RESEARCH
(2021)
Article
Cardiac & Cardiovascular Systems
Fabrizio Vallelonga, Marco Cesareo, Leonardo Menon, Lorenzo Airale, Dario Leone, Anna Astarita, Giulia Mingrone, Maria Tizzani, Enrico Lupia, Franco Veglio, Alberto Milan
Summary: This study investigated cardiac and vascular hypertension mediated organ damage (HMOD) in hypertensive urgencies (HU) and asymptomatic outpatients with grade 1-3 hypertension. The results showed that patients with HU had a better cardiac HMOD profile than outpatients with grade 3 hypertension.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Luca Monzo, Joao Pedro Ferreira, Zohra Lamiral, Erwan Bozec, Jean-Marc Boivin, Olivier Huttin, Marilucy Lopez-Sublet, Nicolas Girerd, Faiez Zannad, Patrick Rossignol
Summary: This study aimed to investigate the relationship between isolated diastolic hypertension (IDH) and hypertension-related target organ damage (TOD), finding that IDH was not significantly associated with TOD. Further studies are needed to clarify the clinical role of IDH.
CLINICAL CARDIOLOGY
(2021)
Article
Peripheral Vascular Disease
Yi Cheng, Chang-Sheng Sheng, Jian-Feng Huang, Dong-Yan Zhang, Ming-Xuan Li, Yi-Bang Cheng, De-Wei An, Qian-Hui Guo, Ying Wang, Qi-Fang Huang, Ting-Yan Xu, Yan Li, Ji-Guang Wang
Summary: There is seasonal variation in nighttime blood pressure, with the highest levels in summer and the lowest levels in winter. Nighttime blood pressure is positively associated with renal injury in terms of urinary albumin excretion, as well as with other markers of target organ damage. The association between nighttime systolic blood pressure and urinary albumin excretion is stronger in summer compared to winter.
HYPERTENSION RESEARCH
(2023)
Article
Peripheral Vascular Disease
Christelle Haddad, Pierre-Yves Courand, Constance Berge, Brahim Harbaoui, Pierre Lantelme
Summary: This study explored the association between cortisol levels and blood pressure, organ damage, and metabolic parameters in hypertensive patients. Results showed that cortisol weakly influenced blood pressure levels independently from plasma aldosterone, particularly in older patients. Additionally, there was a weak association between cortisol levels and hypertensive-mediated organ damage, suggesting a potential interest in testing specific treatments targeting cortisol excess in selected hypertensive patients.
JOURNAL OF HYPERTENSION
(2021)
Article
Peripheral Vascular Disease
Janis M. Nolde, Marcio Galindo Kiuchi, Revathy Carnagarin, Shaun Frost, Dennis Kannenkeril, Leslie Marisol Lugo-Gavidia, Justine Chan, Anu Joyson, Vance B. Matthews, Lakshini Y. Herat, Omar Azzam, Markus P. Schlaich
Summary: The study revealed that supine blood pressure measurements may be a valid surrogate for night-time blood pressure when ambulatory monitoring is not accessible, and might be more closely related to hypertensive-mediated organ damage compared to other blood pressure measurement modalities.
JOURNAL OF CLINICAL HYPERTENSION
(2021)
Editorial Material
Peripheral Vascular Disease
Cesare Cuspidi, Stefano Carugo, Marijana Tadic
Summary: The study suggests that effective 24-hour blood pressure control and reduction in blood pressure variability may lead to regression of subclinical cardiac damage. However, caution is needed in drawing firm conclusions, and further research is necessary to determine the correlation between reduction of blood pressure variability and regression in cardiac and extracardiac organ damage.
JOURNAL OF CLINICAL HYPERTENSION
(2021)
Review
Peripheral Vascular Disease
Guido Grassi, Jennifer Vanoli, Rita Facchetti, Giuseppe Mancia
Summary: The study examines the relationship between serum uric acid levels, office and out-of-office blood pressure, and organ damage. The findings show that serum uric acid values are directly related to various factors that contribute to cardiovascular risk determination. These factors include blood glucose, cholesterol levels, body mass index, and creatinine levels. The study also reveals that serum uric acid levels are associated with left ventricular mass index and blood pressure values, both in office and out-of-office settings. White-coat hypertension and masked hypertension are characterized by increased serum uric acid levels, which are also linked to different indices of blood pressure variability. There was no significant difference in serum uric acid levels based on the dipping or non-dipping nocturnal blood pressure profile. The data collected in the PAMELA study demonstrate the close relationship between serum uric acid levels and blood pressure values, regardless of the patterns of blood pressure increase and nighttime blood pressure profile. The study also suggests that increased serum uric acid levels may contribute to the development of new hypertension and left ventricular hypertrophy.
CURRENT HYPERTENSION REPORTS
(2022)
Article
Peripheral Vascular Disease
Wenling Zheng, Jianjun Mu, Yu Yan, Chao Chu, Xianming Su, Ziyue Man, Wei Zhang, Dan Luo
Summary: This study aimed to investigate the association between longitudinal blood pressure trajectories in early life and cardiovascular risk assessed by target organ damage in adulthood. The results showed that persistently high or increasing blood pressure trajectories in early life were associated with an increased risk of cardiovascular diseases, as indicated by higher carotid intima-media thickness and left ventricular hypertrophy. Therefore, identifying blood pressure trajectories in early life can help predict the cardiovascular risk in midlife.
HYPERTENSION RESEARCH
(2023)
Article
Multidisciplinary Sciences
Lei Shao, Ling Xiao Zhou, Liang Xu, Wen Bin Wei
Summary: The Beijing Eye Study 2011 found that in cases of hypertension, patients with hypertensive retinopathy had significantly thicker subfoveal choroidal thickness, which was significantly associated with the stage of hypertensive retinopathy. However, subfoveal choroidal thickness was not significantly associated with diastolic blood pressure, history of hypertension, or years of hypertension.
SCIENTIFIC REPORTS
(2021)
Article
Obstetrics & Gynecology
Meddy N. Bongers-Karmaoui, Clarissa J. Wiertsema, Annemarie G. M. G. J. Mulders, Wim A. Helbing, Alexander Hirsch, Arno A. W. Roest, Vincent W. V. Jaddoe, Romy Gaillard
Summary: This study aimed to examine the association between gestational hypertensive disorders and gestational blood pressure with subclinical changes in cardiac structure and function of offspring. The results showed that offspring exposed to pre-eclampsia had lower right ventricular ejection fraction. Higher maternal diastolic blood pressure in early and late pregnancy was associated with lower left and right ventricular end-diastolic volumes. There were no consistent associations with other cardiac outcomes.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2023)
Article
Surgery
Diederik P. D. Suurd, Wessel M. C. M. Vorselaars, Dirk-Jan Van Beek, Inne H. M. Borel Rinkes, Wilko Spiering, Gerlof D. Valk, Menno R. Vriens
Summary: The objective of this study was to investigate the postoperative trend in blood pressure-related outcomes during the year following adrenalectomy for primary aldosteronism. The results showed that antihypertensive drug use and home blood pressure measurements decreased substantially within the first month after adrenalectomy and remained stable during the rest of the year. This suggests that blood pressure-related outcomes can be reliably assessed early after adrenalectomy and questions the need for routine long-term follow-up.
Article
Obstetrics & Gynecology
Jianshu Chen, Qiongying Wang, Ying Pei, Ningyin Li, Junchen Han, Jing Yu
Summary: The study found that higher serum free androgen index (FM) levels in postmenopausal hypertensive women are associated with abnormal blood pressure regulation and more serious target organ damage. FM is closely related to 24-hour systolic blood pressure average real variation (ARV) and 24-hour diastolic blood pressure ARV in postmenopausal hypertensive women.
MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY
(2021)
Article
Medicine, General & Internal
Nestor Vazquez-Agra, Ana-Teresa Marques-Afonso, Anton Cruces-Sande, Ignacio Novo-Veleiro, Jose-Enrique Lopez-Paz, Antonio Pose-Reino, Alvaro Hermida-Ameijeiras
Summary: The study found that the influence of inflammatory markers on organ damage is not directly related to circadian blood pressure changes, with certain inflammatory markers strongly correlated with HMOD.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Biochemistry & Molecular Biology
Yuta Okamura, Ryo Niijima, Satoshi Kameshima, Tomoko Kodama, Kosuke Otani, Muneyoshi Okada, Hideyuki Yamawaki
Summary: Hypertension is a major risk factor for cardiovascular diseases, caused by various abnormalities including blood vessel contractibility. This study investigated the effects of human omentin-1 on hypertensive complications in aged SHR. It was found that omentin-1 tended to improve left ventricular and renal failure in SHR, indicating its potential therapeutic role in hypertensive complications.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Emergency Medicine
Michael J. Burla, Aaron M. Brody, Robert D. Welch, Mark J. Favot
JOURNAL OF EMERGENCY MEDICINE
(2015)
Article
Emergency Medicine
Michael J. Burla, Joseph Benjamin
JOURNAL OF EMERGENCY MEDICINE
(2016)
Article
Peripheral Vascular Disease
Phillip D. Levy, Robina Josiah Willock, Michael Burla, Aaron Brody, James Mahn, Alexander Marinica, Samar A. Nasser, John M. Flack
JOURNAL OF THE AMERICAN SOCIETY OF HYPERTENSION
(2016)
Editorial Material
Emergency Medicine
Hani I. Kuttab, Mark Chottiner, Asadolah Movahedan, Nadim M. Hafez, John Purakal
ANNALS OF EMERGENCY MEDICINE
(2019)
Article
Emergency Medicine
Amanda Jurvis, Michael J. Burla
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2019)
Editorial Material
Emergency Medicine
Arthur J. Pope, Hani I. Kuttab, John Purakal
ANNALS OF EMERGENCY MEDICINE
(2019)
Article
Critical Care Medicine
Alex J. Gregorowicz, Patrick G. Costello, David A. Gajdosik, John Purakal, Natasha N. Pettit, Samantha Bastow, Michael A. Ward
CRITICAL CARE MEDICINE
(2020)
Letter
Critical Care Medicine
Erron M. Rourke, Hani I. Kuttab, Joseph D. Lykins, Michelle D. Hughes, Eric P. Keast, Jason A. Kopec, Kristen Wroblewski, John Purakal, Michael A. Ward
CRITICAL CARE MEDICINE
(2021)
Article
Critical Care Medicine
Michael A. Ward, Hani I. Kuttab, D. Joseph, Kristen Wroblewski, Michelle D. Hughes, Eric P. Keast, Jason A. Kopec, Erron M. Rourke, John Purakal
Summary: This study found that under-dosing of 30by3 in underweight patients may significantly increase mortality, while fluid dosing did not impact mortality for obese patients. There is a difference in the impact of actual body weight and ideal body weight on 30by3 dosing.
JOURNAL OF INTENSIVE CARE MEDICINE
(2022)
Article
Multidisciplinary Sciences
Justine Seidenfeld, Anna Tupetz, Cassandra Fiorino, Alexander Limkakeng, Lincoln Silva, Catherine Staton, Joao R. N. Vissoci, John Purakal
Summary: This study analyzed the experiences of COVID-19 patients in a healthcare system in North Carolina, identifying major themes including COVID-19 knowledge, diagnosis, patient risk perception, medical care experience, and long-term recovery difficulties. The findings provide insights for targeted interventions to reduce COVID-19 transmission in high-risk communities and enhance the patient experience during the course of COVID-19 illness.
Article
Emergency Medicine
Katherine Lutz, Jessica Roberts Williams, John David Purakal
Summary: Intimate partner violence recognition remains low in emergency departments, partly due to barriers experienced by providers. This study found that previous training in intimate partner violence is associated with higher readiness scores. Physicians have higher knowledge scores compared to registered nurses. Cultural competence positively influences readiness, communication, and practices related to intimate partner violence.
JOURNAL OF EMERGENCY NURSING
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Michael J. Burla, Judith Boura, Lihua Qu, Jeffrey S. Ditkoff, David A. Berger
EMERGENCY RADIOLOGY
(2018)
Article
Emergency Medicine
Michael J. Twiner, Alexander L. Marinica, Kenneth Kuper, Allen Goodman, James J. Mahn, Michael J. Burla, Aaron M. Brody, Justin A. Carroll, Robina Josiah Willock, John M. Flack, Samar A. Nasser, Phillip D. Levy
ACADEMIC EMERGENCY MEDICINE
(2017)
Article
Emergency Medicine
Suprat Saely Wilson, Gregory M. Kwiatkowski, Scott R. Millis, John D. Purakal, Arushi P. Mahajan, Phillip D. Levy
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2017)
Letter
Emergency Medicine
Zhao-Yu Hsieh, Chen-Xiong Hsu
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Editorial Material
Emergency Medicine
Laura E. Walker, Jessica A. Stanich, Fernanda Bellolio
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Letter
Emergency Medicine
E. Tekin
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Article
Emergency Medicine
Amanda S. Dupont, Patrick S. Walsh
Summary: Recent research indicates that children who unintentionally ingest cannabis often undergo extensive additional testing, such as head imaging or lumbar puncture. However, the yield of these tests is limited. While head imaging and lumbar puncture are frequently performed, diagnoses such as skull fracture, intracranial hemorrhage, intracranial neoplasm, meningitis, or intracranial abscess are rare. Additionally, discharge diagnoses related to other drugs are infrequent. The most common co-diagnoses are cocaine and opioids. Therefore, prompt consideration of cannabis ingestion and quick identification through testing may result in more effective neuroimaging outcomes.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Letter
Emergency Medicine
Mio Nagata, Shunsuke Kudo, Motoyasu Nakamura
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Article
Emergency Medicine
Andy Hung-Yi Lee, Katherine Dickerson Mayes, Regan Marsh, Christina Toledo-Cornell, Eric Goralnick, Michael Wilson, Leon D. Sanchez, Alice Bukhman, Damarcus Baymon, Dana Im, Paul C. Chen
Summary: This study assessed the disparities in transferring patients from an academic medical center emergency department to a community hospital general medical service, revealing healthcare disparities among different patient populations.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Article
Emergency Medicine
Annabelle Croskey, William Trautman, David Barton, Mary Kathleen Ratay, Joshua Shulman
Summary: This case report describes a successful management of ocular palytoxin exposure in a young male, highlighting the importance of prompt recognition and treatment of ocular PTX toxicity.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Article
Emergency Medicine
Matthew K. Kolbeck, Rachel F. Schult, Nicholas Nacca
Summary: This article presents four cases of adolescents who experienced seizures after acute fluoxetine overdose. Although seizures are an uncommon complication after fluoxetine overdose, they occurred in some patients at doses lower than those reported in the literature.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Editorial Material
Emergency Medicine
Daven Patel, John Bailitz, Simone Ymson, Jonas Neichin, Gary D. Peksa, Michael Gottlieb
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Article
Emergency Medicine
Amichai Gutgold, Shaden Salameh, Jeries Nashashibi, Yonatan Gershinsky
Summary: This study aimed to test the prognosis of patients with a pH lower than 6.9 on emergency department admission. The findings showed that a small but significant portion of these patients survived at least 24 hours and until hospital discharge.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Article
Emergency Medicine
Na-Yeon Emily Song, Ki Hong Kim, Ki Jeong Hong
Summary: This study aimed to evaluate the effect of the duration of no-flow (NF) interval on the vaso-pressor effect of initial epinephrine administration in a porcine model of cardiac arrest. The results showed that a shorter NF interval can enhance the vasopressor effect of epinephrine.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Article
Emergency Medicine
Kenneth A. Scheppke, Paul E. Pepe, Jonathan Jui, Remle P. Crowe, Eric K. Scheppke, Nancy G. Klimas, Aileen M. Marty
Summary: This study reported cases of rapid and complete remission of severe long COVID after receiving monoclonal antibody treatment. The findings suggest that monoclonal antibody infusions may be effective in treating severe debilitation caused by long COVID.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Article
Emergency Medicine
Suhrith Bhattaram, Varsha S. Shinde
Summary: Nerve blocks have emerged as promising options for targeted pain relief in the Emergency Department, providing effective analgesia without compromising motor function. The successful use of ultrasound-guided genicular nerve blocks (GNBs) in this case series demonstrates their potential as an alternative to traditional nerve blocks and opioid-based pain control strategies in the ED.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Article
Emergency Medicine
Rick Kye Gan, Jude Chukwuebuka Ogbodo, Yong Zheng Wee, Ann Zee Gan, Pedro Arcos Gonzalez
Summary: The aim of this study was to evaluate and compare the performance of ChatGPT, Google Bard, and medical students in performing START triage during mass casualty situations. The results showed that Google Bard had significantly higher accuracy compared to ChatGPT, while there was no significant difference between Google Bard and medical students.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Article
Emergency Medicine
Nancy Clemens, Paria M. Wilson, Matthew J. Lipshaw, Holly Depinet, Yin Zhang, Michelle Eckerle
Summary: This study compared clinical features and outcomes between pediatric sepsis patients with blood cultures positive versus negative for bacterial pathogens. The results showed that children with blood culture positive sepsis had higher rates of organ dysfunction, a larger base deficit, and higher procalcitonin levels.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)