Article
Multidisciplinary Sciences
Emil Paluch, Jakub Szperlik, Lukasz Lamch, Kazimiera A. Wilk, Ewa Oblak
Summary: Research on the antifungal mechanism of cationic dicephalic surfactants on Candida albicans showed that their action is different from most known surfactants, inducing oxidative stress and increasing cell membrane permeability without compromising its integrity. These findings significantly expand the understanding of multifunctional cationic surfactants and suggest their potential applications as antibiofilm agents in medicine or industry.
SCIENTIFIC REPORTS
(2021)
Article
Immunology
Tomonori Takano, Hayami Kudo, Shuhei Eguchi, Asami Matsumoto, Kentaro Oka, Yukitaka Yamasaki, Motomichi Takahashi, Takuro Koshikawa, Hiromu Takemura, Yuka Yamagishi, Hiroshige Mikamo, Hiroyuki Kunishima
Summary: The concentrations of lactobacillus metabolites have varied effects on the suppression of Candida albicans biofilms. Lactate and hydrogen peroxide produced by lactobacillus are both required to inhibit C. albicans growth. Lactobacillus strains that significantly inhibit biofilm formation also inhibit C. albicans adhesion to epithelial cells.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2023)
Article
Immunology
Yasmine H. Tartor, Gamal A. Elmowalid, Mohamed N. Hassan, Asmaa Shaker, Dalia F. Ashour, Taisir Saber
Summary: This study investigated the inhibition of Candida albicans biofilms and the interactions between biofilms and phagocytes in the presence of essential oils, biological and chemical agents, or fluconazole. The results showed that cinnamon oil, sodium dodecyl sulfate (SDS), and cetyltrimethylammonium bromide (CTAB) were the most effective inhibitors of C. albicans biofilms, while fluconazole was ineffective. Additionally, it was found that phagocytes could rapidly engulf C. albicans cells in biofilms treated with cinnamon oil, Enterococcus faecalis cell-free supernatant (CFS), or SDS.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Medicine, Research & Experimental
Longfei Yang, Lili Zhong, Zhiming Ma, Yujie Sui, Jia'nan Xie, Xin Liu, Tonghui Ma
Summary: Alantolactone has shown antifungal activities against Candida albicans and can reduce its adhesion and biofilm formation. Therefore, it may be a promising candidate for developing antifungal drugs.
BIOMEDICINE & PHARMACOTHERAPY
(2022)
Article
Dentistry, Oral Surgery & Medicine
Andrea Ardizzoni, Giorgia Boaretto, Eva Pericolini, Diego Pinetti, Alessandra Capezzone de Joannon, Lucia Durando, Lorella Ragni, Elisabetta Blasi
Summary: This study demonstrates for the first time that benzydamine and mouthwashes containing benzydamine can affect Candida albicans biofilm formation and counteract biofilm persistence and regrowth.
CLINICAL ORAL INVESTIGATIONS
(2022)
Article
Microbiology
Natalia Gomez-Casanova, Tania Lozano-Cruz, Juan Soliveri, Rafael Gomez, Paula Ortega, Jose Luis Copa-Patino, Irene Heredero-Bermejo
Summary: Candida albicans is a significant human pathogen that is resistant to drugs and forms biofilms, making treatment difficult. This study evaluated the in vitro ability of cationic carbosilane dendrons to eradicate C. albicans biofilms, with the second generation dendron showing promising antifungal activity.
Article
Microbiology
Emerenziana Ottaviano, Giovanna Baron, Laura Fumagalli, Jessica Leite, Elisa Adele Colombo, Angelica Artasensi, Giancarlo Aldini, Elisa Borghi
Summary: The study demonstrated the efficacy of urinary cranberry metabolites VAL and 4-HBA in inhibiting Candida adhesion and biofilm formation in vitro. These metabolites interfered with yeast adhesion by modulating key gene expression, leading to a significant reduction in biofilm biomass and metabolic activity. The findings suggest that VAL and 4-HBA could be potential targets for drug development in preventing genitourinary Candida infections.
Article
Immunology
Soon-Hwan Oh, Helene Martin-Yken, David A. Coleman, Etienne Dague, Lois L. Hoyer
Summary: In this study, a monoclonal antibody MAb 2-E8 was raised against a peptide from the adhesive domain of Hwp1 protein in Candida albicans. The specificity of MAb 2-E8 for Hwp1 was confirmed, and it can be used to detect Hwp1 protein in C. albicans and C. dubliniensis. This research is important for further understanding the role of Hwp1 in the biology and pathogenesis of Candida albicans.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Food Science & Technology
Quan Lin, Yanxin Li, Maokun Sheng, Jiaman Xu, Xiaoyan Xu, Jintae Lee, Yulong Tan
Summary: In recent years, there has been an increasing trend in Candida contamination caused by Candida mastitis, which has a significant impact on the hygienic quality of raw milk and dairy products. The biofilm produced by Candida albicans plays a critical role in fungal infection by protecting the fungus from host defense and drug attacks. Therefore, finding effective means to reduce the biofilm and drug resistance of Candida albicans has become an urgent problem. This study investigated the anti-biofilm effect of berberine-loaded chitosan nanoparticles on Candida albicans and explored the antifungal mechanism of released berberine.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2023)
Article
Biotechnology & Applied Microbiology
Jingxiao Zhang, Jian Sun, Yu Zhang, Min Zhang, Xin Liu, Longfei Yang, Yongjie Yin
Summary: This study examined the effects of dehydrocostus lactone (DL) on Candida albicans and its biofilms. The results showed that DL can inhibit the growth and biofilm formation of Candida albicans, and it achieves this through damaging the cell membrane and inducing reactive oxygen species (ROS) production.
Article
Microbiology
Eunsoo Do, Max Cravener, Manning Y. Huang, Gemma May, C. Joel McManus, Aaron P. Mitchell
Summary: In this study, natural variation in the fungal pathogen Candida albicans was investigated to understand the gene regulatory control of biofilm formation, an important aspect of its virulence. Collaboration between the transcription factors Efg1 and Wor1 was found to drive natural variation in biofilm formation and gene expression. These findings highlight the importance of studying natural isolates to uncover unexpected features of gene function.
Article
Biochemistry & Molecular Biology
Lana Glerieide Silva Garcia, Maria Gleiciane da Rocha, Laysa Rocha Lima, Arcelina Pacheco Cunha, Jonathas Sales de Oliveira, Ana Raquel Colares de Andrade, Nagila Maria Pontes Silva Ricardo, Waldemiro Aquino Pereira-Neto, Jose Julio Costa Sidrim, Marcos Fabio Gadelha Rocha, Rodrigo Silveira Vieira, Raimunda Samia Nogueira Brilhante
Summary: The study aimed to produce and characterize chitosan microparticles loaded with essential oils, evaluate their anti-Candida activity, and assess essential oil release profile. The results showed that these microparticles have promising antibiofilm activity against Candida.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Biophysics
Florian Weber, Louise Morais Dornelas-Figueira, Nora Hafiane, Daria Zaytseva-Zotova, Alejandro Barrantes, Fernanda Cristina Petersen, Hanna Tiainen
Summary: Oral biofilms can cause infections and diseases, and the role of fungi is often overlooked in research. Plant-derived polyphenolic coatings may be effective in resisting microbial growth and adhesion, but further research is needed.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2022)
Article
Chemistry, Physical
Avi Meirowitz, Arkadi Rahmanov, Eti Shlomo, Helena Zelikman, Eran Dolev, Nir Sterer
Summary: The study investigated the effect of different denture fabrication methods on Candida albicans adhesion to denture base samples. 3D printing increased microbial cell adhesion, while computerized milling decreased it compared to traditional heat curing. The results were associated with mucin adsorption levels rather than surface roughness.
Article
Microbiology
Sabi Pokhrel, Nawarat Boonmee, Orawan Tulyaprawat, Sujiraphong Pharkjaksu, Iyarit Thaipisutikul, Phoom Chairatana, Popchai Ngamskulrungroj, Chalermchai Mitrpant
Summary: Biofilm formation is an important virulence factor for the pathogenesis of Candida albicans. This study used the zebrafish model to evaluate the in vivo virulence of strains with different biofilm formation strengths. The results showed that stronger biofilm formation was associated with shorter survival time in zebrafish and higher up-regulation of biofilm-associated genes.
Article
Biotechnology & Applied Microbiology
E. Paluch, J. Szperlik, T. Czuj, M. Cal, L. Lamch, K. A. Wilk, E. Oblak
Summary: The research found that the mechanism of perforation of cell membranes commonly associated with surfactants does not apply to cationic dicephalic surfactants, which instead act by increasing cell membrane permeability, leading to lipid droplet aggregation and morphological changes in fungal cells. Additionally, these compounds induce oxidative stress within cells, including increased production of superoxide anion radicals and mitochondrial oxidative stress.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Julita Kulbacka, Kazimiera A. Wilk, Urszula Bazylinska, Magda Dubinska-Magiera, Stanislaw Potoczek, Jolanta Saczko
Summary: Nano carriers loaded with curcumin and differing in surface charge were evaluated for transport efficacy in different types of cells with electroporation. The drug delivery properties of the obtained PLA nanocarriers enhanced by electroporation were assessed in human colon cancer cells, normal rat muscle cells, and cells free of voltage-gated ion channels. The highest photodynamic activity was observed in anionic nanocarriers stabilized by C-12(COONa)(2) surfactant.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Emil Paluch, Paulina Sobierajska, Piotr Okinczyc, Jaroslaw Widelski, Anna Duda-Madej, Barbara Krzyzanowska, Pawel Krzyzek, Rafal Ogorek, Jakub Szperlik, Jacek Chmielowiec, Grazyna Gosciniak, Rafal J. Wiglusz
Summary: The aim of this research was to investigate the antiadhesive and antibiofilm properties of nanocrystalline apatites doped and co-doped with noble metal ions against drug-resistant strains of bacteria. The results showed that these materials effectively inhibit adhesion and biofilm formation of the bacteria strains, and have no significant cytotoxic effect on fibroblasts.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Joanna Wezgowiec, Marta Tsirigotis-Maniecka, Jolanta Saczko, Mieszko Wieckiewicz, Kazimiera A. Wilk
Summary: This study characterized hydrogel micro- and macro-particles designed to deliver curcumin to human colon cancer cells. The microparticles encapsulated less payload and released content more slowly than the macroparticles. Curcumin-loaded carriers showed significant impact on cell viability, particularly after incubation with microparticles.
Article
Biochemistry & Molecular Biology
Weronika Szczesna, Marta Tsirigotis-Maniecka, Lukasz Lamch, Lilianna Szyk-Warszynska, Ewa Zboinska, Piotr Warszynski, Kazimiera A. Wilk
Summary: The study developed multilayered hydrogel microcarriers with multiple functionalities and successfully loaded them with chemotherapeutic curcumin (CUR). The surface of the microcarriers was coated with antimicrobial functionalized polyelectrolytes using the layer-by-layer technique. The functional layers exhibited good viscoelastic properties, and the release of the drug from the microcarriers followed a hybrid model. Furthermore, the antimicrobial activity of the functionalized microcarriers against Staphylococcus aureus and Serratia marcescens was significantly enhanced.
Article
Microbiology
Jaroslaw Widelski, Piotr Okinczyc, Emil Paluch, Tomasz Mroczek, Jakub Szperlik, Magdalena Zuk, Zbigniew Sroka, Zuriyadda Sakipova, Ioanna Chinou, Krystyna Skalicka-Wozniak, Anna Malm, Izabela Korona-Glowniak
Summary: There is a growing interest in alternative therapies for eradicating Helicobacter pylori (H. pylori) and treating stomach diseases and preventing stomach cancer. This study focused on the antimicrobial activity of ethanol extracts from 11 propolis samples against H. pylori, as well as other bacteria and yeast species. The propolis from Ukraine showed the highest antimicrobial activity against H. pylori, and the phytochemical analysis revealed that the composition of poplar propolis correlated with higher antibacterial activity.
Article
Chemistry, Physical
Guru Karthikeyan Thirunavukkarasu, Jana Bacova, Olivier Monfort, Ewa Dworniczek, Emil Paluch, Muhammad Bilal Hanif, Sajid Rauf, Monika Motlochova, Jan Capek, Karol Hensel, Gustav Plesch, Grzegorz Chodaczek, Tomas Rousar, Martin Motola
Summary: This study compared two TiO2 nanopowders in terms of toxicity, photoinduced antimicrobial and antibiofilm properties, and photocatalytic activity. TiAP showed higher efficiency in photocatalysis and bacterial inactivation compared to P25.
APPLIED SURFACE SCIENCE
(2022)
Article
Cell Biology
Agnieszka A. Pilarska, Agnieszka Wolna-Maruwka, Alicja Niewiadomska, Jaroslaw Grzadziel, Anna Galazka, Emil Paluch, Klaudia Borowiak, Krzysztof Pilarski
Summary: This paper analyzes the impact of the diatomaceous earth/peat (DEP; 3:1) microbial carrier on the bacterial microbiome and biofilm development in anaerobic digestion of confectionery waste. The research reveals that DEP is a suitable carrier for both mesophilic and thermophilic AD. Next-generation sequencing shows that DEP has a modifying effect on the bacterial microbiome, leading to changes in bacterial diversity. The addition of DEP also contributes to microbial adhesion and the formation of a stable biofilm in the microfluidic system.
Article
Biochemistry & Molecular Biology
Piotr Okinczyc, Jaroslaw Widelski, Monika Ciochon, Emil Paluch, Anna Bozhadze, Malkhaz Jokhadze, Gocha Mtvarelishvili, Izabela Korona-Glowniak, Barbara Krzyzanowska, Piotr Marek Kus
Summary: This study characterized the phytochemical composition and antimicrobial/antioxidant activity of Georgian propolis. The results showed that the propolis extracts from Georgia exhibited strong activity against Gram-positive bacteria, weaker activity against Gram-negative strains, and strong antioxidant properties. The phytochemical profile of Georgian propolis was mainly characterized by flavonoids, free phenolic acids, and their esters. The primary plant precursor of Georgian propolis is black poplar, while the secondary is aspen poplar.
Article
Biochemistry & Molecular Biology
Jaroslaw Widelski, Katarzyna Gawel-Beben, Karolina Czech, Emil Paluch, Olga Bortkiewicz, Solomiia Kozachok, Tomasz Mroczek, Piotr Okinczyc
Summary: Tyrosinase is a key enzyme in melanogenesis, and its hyperactivity can cause hyperpigmentation disorders. This study assessed the tyrosinase inhibitory potential of six propolis extracts and found that they showed potent inhibitory activity. The extracts also exhibited antioxidant activity and various phytochemical composition. These findings suggest that the tested propolis extracts could be used in cosmeceutical and medical applications.
Article
Nanoscience & Nanotechnology
Monika U. Weber, Janusz J. Petkowski, Robert E. Weber, Bartosz Krajnik, Slawomir Stemplewski, Marta Panek, Tomasz Dziubak, Paulina Mrozinska, Anna Piela, Emil Paluch
Summary: We experimentally validated the theoretical design constraints of the ring electrode architecture and compared its performance with the dot electrode structure. The ring structure achieved 99% efficiency in bacterial capture and showed a significantly faster response to the electric field. We also identified critical design constraints for high efficiency bacterial capture.
Article
Biochemistry & Molecular Biology
Agnieszka A. Pilarska, Anna Marzec-Grzadziel, Emil Paluch, Krzysztof Pilarski, Agnieszka Wolna-Maruwka, Adrianna Kubiak, Tomasz Kaluza, Tomasz Kulupa
Summary: This study conducted anaerobic digestion on confectionery waste using granular polylactide (PLA) as a cell carrier. The results showed that PLA significantly enhanced bacterial proliferation without affecting microbiome biodiversity. The addition of PLA also promoted the growth of biofilm surface area.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Jaroslaw Widelski, Piotr Okinczyc, Katarzyna Susniak, Anna Malm, Emil Paluch, Asanali Sakipov, Gulsim Zhumashova, Galiya Ibadullayeva, Zuriyadda Sakipova, Izabela Korona-Glowniak
Summary: In this study, Kazakh propolis was investigated, and it was found that it contains abundant markers and has strong antimicrobial activity, which may be considered as a medicament in the future.
Article
Biochemistry & Molecular Biology
Marcin Bartman, Sebastian Balicki, Lucyna Holysz, Kazimiera A. Wilk
Summary: Water-in-oil nanoemulsions stabilized with amino acid surfactants are effective detergents for removing graffiti coatings from sensitive surfaces. The nanostructured fluids, consisting of non-toxic and eco-friendly components, were obtained using high-pressure homogenization. By optimizing the formulation, the most effective detergent was determined. The removal of graffiti depends more on the energetic properties and microstructure of the paint coatings than on the properties of the substrates.
Article
Chemistry, Physical
Ewelina Jarek, Zofia Krasinska-Krawet, Tomasz Kruk, Lukasz Lamch, Sylwia Ronka, Kazimiera A. Wilk, Piotr Warszynski
Summary: The adsorption properties of the hydrophobically functionalized polyelectrolyte were investigated at water/air and water/decane interfaces, as well as on the solid surface. It was found that surface activity was practically independent of the grafting ratio for C-16 side chains, while a lower grafting ratio seemed to increase surface activity for C-12 side chains. QCM-D and FTIR-ATR experiments confirmed the adsorption of the hydrophobized copolymer at PEM along with modification of water structure at the interface.
COLLOIDS AND INTERFACES
(2021)
Article
Biophysics
Cristina Potrich, Anna Pedrotti, Cecilia Pederzolli, Lorenzo Lunelli
Summary: This study developed different functional surfaces for capturing exosomes and verified their effectiveness through experiments. Among them, the negatively-charged surface performed the best, capturing a large number of exosomes and successfully analyzing their biomarkers.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Brojendra Nath Saren, Srushti Mahajan, Mayur Aalhate, Rahul Kumar, Essha Chatterjee, Indrani Maji, Ujala Gupta, Santosh Kumar Guru, Pankaj Kumar Singh
Summary: This study developed P-selectin-targeted dasatinib nanoparticles coated with chitosan and fucoidan (DST-CH-FUC-NPs), which showed sustained release, reduced hemolytic potential, increased cytotoxicity and cellular uptake compared to free dasatinib. These nanoparticles also demonstrated enhanced ROS production, mitochondrial membrane potential damage, apoptosis induction, cell migration inhibition, and disruption of lysosomal membrane integrity.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Weiping Deng, Xiaohui Li, Ya Li, Zhongbing Huang, Yulin Wang, Ning Mu, Juan Wang, Tunan Chen, Ximing Pu, Guangfu Yin, Hua Feng
Summary: This study demonstrates the importance of chirality in nerve repair by constructing a GO-phenylalanine derivative hydrogel system. In vivo experiments show that the dextro group significantly improves functional recovery and histological restoration in rat sciatic nerve repair models. The doped GO promotes angiogenesis and myelination. These results suggest that chirality plays a crucial role in promoting nerve regeneration.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Xiaoyan Wang, Jin Gao, Yu Gao, Linlin Zhang, Congchao Xu, Qintong Li, Lin Li, Jianliang Xue
Summary: In this study, a highly effective surfactant producer strain, Bacillus Cereus GX7, was isolated from the oil tank bottom sludge of Shengli Oil Field in China. The biosurfactant produced by GX7 was identified as surfactin, a lipopeptide surfactant, through TLC, FT-IR, and LC-MS/MS analysis. The fermentation process of GX7 was optimized using single-factor experiments, focusing on the composition of fermentation medium and fermentation conditions. Glucose and peptone were found to be the best carbon and nitrogen sources, and the optimum temperature, inoculum amount, pH, rotation speed, and fermentation time for the strain were determined to be 30°C, 1%, 7.5, 150 rpm, and 48 h, respectively. After optimization, the surface tension and emulsification index of the fermentation broth were 26.84 mN/m and 57.84%, respectively. Furthermore, the biosurfactant produced by GX7 demonstrated good stability over a wide range of temperature, pH, and salt concentration.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Rodney Marcelo do Nascimento, Christine Grauby-Heywang, Houssem Kahli, Nesrine Debez, Laure Beven, Ivan Helmuth Bechtold, Touria Cohen Bouhacina
Summary: This article presents a theoretical model based on thermodynamic rules to assess the early stages of bacterial biofilm formation on different material surfaces. By utilizing morphological characteristics of bacteria and Atomic Force Microscopy images, the model generates a dataset of energetically minimized states, which can be correlated with bacterial adhesion states.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Filipa A. L. S. Silva, Licinia Timochenco, Raquel Costa-Almeida, Jose Ramiro Fernandes, Susana G. Santos, Fernao D. Magalhaes, Artur M. Pinto
Summary: The study demonstrates that by photoreducing nanosized graphene oxide using ultraviolet radiation, nanometric particles with high light-to-heat conversion efficiency and water stability can be obtained. These nanomaterials exhibit high absorption in the near-infrared region and show no cytotoxicity towards human cells, indicating their potential for safe therapy.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
D. Costa, V. De Matteis, F. Treso, G. Montani, M. Martino, R. Rinaldi, M. Corrado, M. Cascione
Summary: This review primarily discusses the relationship between contact lens discomfort (CLD) and the surface properties of contact lenses (CLs), specifically the coefficient of friction (CoF). The review emphasizes the importance of introducing a standardized protocol for measuring CoF and calls for a more precise evaluation of the relationship between surface properties and comfort in CLs users.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Debdip Brahma, Tamal Sarkar, Rupal Kaushik, Akshay Narayan Sarangi, Amar Nath Gupta
Summary: This in-vitro study evaluates the effect of reactive oxygen species (ROS) on the structural rearrangement of elastin. The results show that oxidative stress leads to a decrease in protein size and changes in secondary structure, potentially promoting protein aggregation. This study is important for therapeutics aiming to prevent elastin degradation and aging.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Xin Yang, Qiang Wang, Chaoxi Yan, Degang Huang, Yinchang Zhang, Huazheng He, Shouliang Xiong, Congming Li, Pingbo Chen, Tingjun Ye, Dan Hu, Lei Wang
Summary: This study presents a practical and effective strategy to improve osseointegration in patients with osteoporosis. By coating titanium implants with polydopamine followed by strontium modification, the bi-functional implants promote bone regeneration and immune regulation. The results show good biocompatibility, sustained release of strontium ions, and stable osseointegration between bone tissues and implants.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Sengwang Fu, Jianping Zhu, Zhijun Jiang, Yue Cao, Yufei Chen, Lihao Zhang, Sunlong Li, Weipeng Lu, Chengbin Miao, Qing He, Qi Li, Weixing Zhang, Lehao Ren, Yachun Li, Hongchao Shi, Cihui Liu
Summary: Effective management of biofluids is crucial for in vivo surgical interventions. Recent advances include self-sealing needles, drug-eluting stents, and shear-thinning hydrogels. However, complications associated with intestinal mucosal injury and secondary damage still persist. In this study, researchers developed an interpenetrating Janus wettability stent coating that enables unidirectional draining of excessive biofluid. They also demonstrated directional biofluid movement using a self-pumping dressing with potential applications in biofluid collection and disease diagnosis through metal ion detection. This integrated system presents an opportunity for designing wound dressings with effective biofluid management and metal ion detection capabilities.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Maryam Hassani, Mojtaba Kamankesh, Mazda Rad-Malekshahi, Kobra Rostamizadeh, Farhad Rezaee, Ismaeil Haririan, Seyed Mojtaba Daghighi
Summary: Bacterial adhesion and biofilm formation on the surface of biomaterial implants is a critical problem, and a polymer brush coating with antiadhesive and antimicrobial properties has proven to be highly effective in resolving this issue.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Huaihong Zhang, Na Liu, Yuting Zhang, Hui Cang, Zhaosheng Cai, Ziqun Huang, Jun Li
Summary: A functionalized cationic polymer, CR-PQAC, was designed and synthesized for photothermal enhanced antimicrobial therapy. The CR-PQAC nanoparticles exhibited significant antibacterial activity and low cytotoxicity against mammalian cells.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Ipsita Sahu, Priyadarshi Chakraborty
Summary: Peptide nanotechnology bridges the gap between materials and biological worlds by utilizing self-assembly of short-peptide building blocks. Hydrogels engineered from these short peptides show great potential in biomedical applications, but their weak mechanical properties and limited functional diversity need to be addressed. Nanoengineering the networks of these hydrogels by incorporating small molecules, polymers, and inorganic/carbon nanomaterials can enhance their mechanical properties and expand their functional diversity.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Hao Wei, Yajun Gu, Ao Li, Panpan Song, Dingding Liu, Feihu Sun, Xiaofeng Ma, Xiaoyun Qian
Summary: In this study, a stable three-dimensional conductive hydrogel was prepared by cross-linking MXenes to Matrigel hydrogel. The conductive hydrogel promotes the proliferation and differentiation of NSCs, providing new strategies for neural tissue engineering.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Yue Zhong, Xiaoli Ge, Juan Zhang, Qun Wei, Feng Wang, Yongke Zhong
Summary: The effect of oxygenic groups on the hemocompatibility of activated carbon was studied through liquid-phase oxidation and subsequent heat treatment. Results showed that the presence of oxygenic groups improved hemocompatibility, while their removal decreased it.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
