4.6 Article

Preparation and application of pyraclostrobin microcapsule formulations

Publisher

ELSEVIER SCIENCE BV
DOI: 10.1016/j.colsurfa.2018.06.009

Keywords

Microcapsule formulations; Pyraclostrobin; Interfacial polymerization; Environmental safety; Spreadability

Funding

  1. Subsidy Project for Outstanding Key Laboratory of Guizhou Province in China [20154004]
  2. Collaborative Innovation Center for Natural Products and Biological Drugs of Yunnan [201225]

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In this paper, pyraclostrobin-loaded polyurea microcapsules were prepared through interfacial polymerization reaction between isocyanates and amines. The microcapsules had size distribution ranging from 0.815 mu m to 8.674 mu m nearly spherical shapes, and excellent encapsulation efficiency (EE > 90%). The release of pyraclostrobin from microcapsules was controlled by diffusion and erosion. The results of acute toxicity to zebrafish, spreadability on rice blades, and control effect on rice blast showed that the microcapsule formulations had significantly decreased toxicity to zebrafish (lower by 8-9-fold than that of emulsifiable concentrate), high spreadability on rice leaves, and satisfactory control efficacy against rice panicle blast (85.03%). This novel microencapsulation technology helps promote the environmental safety and control efficacy of pyraclostrobin.

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