Article
Biochemistry & Molecular Biology
Giuseppina Bonizzi, Lorenzo Zattoni, Maria Capra, Cristina Cassi, Giulio Taliento, Mariia Ivanova, Elena Guerini-Rocco, Marzia Fumagalli, Massimo Monturano, Adriana Albini, Giuseppe Viale, Roberto Orecchia, Nicola Fusco
Summary: Biobanks are crucial for precision medicine research, with specific protocols and guidelines necessary to maintain optimal quality. Standard operating procedures should cover protocols, troubleshooting, and quality controls.
FRONTIERS IN MOLECULAR BIOSCIENCES
(2022)
Article
Entomology
Natalie Lissenden, Jennifer S. Armistead, Katherine Gleave, Seth R. Irish, Jackline L. Martin, Louisa A. Messenger, Sarah J. Moore, Corine Ngufor, Natacha Protopopoff, Richard Oxborough, Angus Spiers, Rosemary S. Lees
Summary: Mosquitoes are becoming increasingly resistant to pyrethroid insecticides, leading to the development of new insecticide-treated nets. However, there is a lack of standardized methods to measure the efficacy of these nets against mosquitoes in the long term.
Article
Integrative & Complementary Medicine
Jun Liu, Nian Wang, Hai-xia Dang, Bing-wei Chen, Li Zhang, Chong Zou, Cheng-liang Zhong, Ju-kai Huang, Qiong Liu, Ya-nan Yu, Meng Jiang, Wei-xiong Liang, Qi-guang Chen, Yong-yan Wang, Chun-ti Shen, Zhong Wang
Summary: The paper summarizes the key content of the Chinese Medicine Data Monitoring Committee (CMDMC) community standard, issued by the China Association of Chinese Medicine, to help sponsors of clinical studies establish and operate CMDMCs for enhancing the scientific integrity and quality of clinical studies.
CHINESE JOURNAL OF INTEGRATIVE MEDICINE
(2021)
Article
Plant Sciences
Avesh Chadee, Masoom Mohammad, Greg C. Vanlerberghe
Summary: In this study, the expression of AOX1a gene in Nicotiana tabacum leaf was found to be influenced by leaf carbohydrate amounts and the relationship between source and sink activity. The expression of AOX1a gene increased when leaves were supplied with exogenous carbohydrates, grown at elevated CO2 concentrations, or subjected to various treatments. These findings offer important insights into the regulation of source-sink balance, photosynthesis, and phloem loading capacity in plants.
JOURNAL OF PLANT PHYSIOLOGY
(2022)
Review
Respiratory System
Zoe L. Saynor, Mathieu Gruet, Melitta A. McNarry, Brend Button, Lisa Morrison, Marlies Wagner, Abbey Sawyer, Helge Hebestrett, Thomas Radtke, Don S. Urquhart
Summary: This article provides guidance on commonly used exercise tests for PwCF and highlights tests no longer suggested for use. It also emphasizes the need for further research in certain areas.
EUROPEAN RESPIRATORY REVIEW
(2023)
Article
Agriculture, Dairy & Animal Science
Jonas Habel, Albert Sundrum
Summary: Based on comprehensive data, this study evaluated the glucose and energy balances of dairy cows before, during, and after the diagnosis of production diseases. It found that glucose availability dropped during the disease phase, leading to potential competition between immune defense and milk synthesis. The reduced dry matter intake and milk yield during disease resulted in decreased glucose availability. Strategies to increase glucogenic carbon availability for immune function during disease in dairy cows should be investigated.
Article
Geosciences, Multidisciplinary
Takaaki Kato, Jieh-Jiuh Wang, Ning-Yu Tsai
Summary: Planning and flexibility are important for emergency management. Defining standard operating procedures (SOPs) can improve emergency responses. Accumulated experiences and different types of emergencies contribute to the development of SOPs. While SOPs have benefits, concerns about their impact on flexibility exist.
INTERNATIONAL JOURNAL OF DISASTER RISK REDUCTION
(2022)
Article
Biochemistry & Molecular Biology
Ayelet Hod, Jayasimha Rayalu Daddam, Gitit Kra, Hadar Kamer, Yuri Portnick, Uzi Moallem, Maya Zachut
Summary: Negative energy balance postpartum is associated with adverse outcomes in dairy cows. The study focuses on determining non-invasive biomarkers in milk that can serve as indicators of negative energy balance. Results show that NEB cows produced more milk and consumed less dry matter compared to PEB cows.
Article
Multidisciplinary Sciences
Giuseppina Bonizzi, Maria Capra, Cristina Cassi, Giulio Taliento, Oriana Pala, Elham Sajjadi, Konstantinos Venetis, Mariia Ivanova, Massimo Monturano, Giuseppe Renne, Lorenzo Zattoni, Elena Guerini-Rocco, Giuseppe Viale, Roberto Orecchia, Nicola Fusco
Summary: Biobanks are crucial for the collection, storage, and sharing of high-quality human biological samples and data. However, accessing the standard operating procedures of biobanks can be challenging, despite efforts to standardize and harmonize them.
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS
(2022)
Article
Agriculture, Dairy & Animal Science
Noemie Vanacker, Henrique Barbosa Hooper, Richard Blouin, Pierre Lacasse
Summary: During the transition period, dairy cows often experience negative energy balance, which can lead to metabolic and immunological disturbances. Previous research has shown a relationship between immune cell dysfunction and increased NEFA concentration. This study aimed to determine the specific effect of NEFA on the immune system, independent of energy balance and other hormonal and metabolic changes. The results revealed that NEFA inhibits immune functions independently of energy balance and causes insulin resistance.
JOURNAL OF DAIRY SCIENCE
(2023)
Article
Biology
Judith M. Hollander, Lingyun Li, Miraj Rawal, Si Kun Wang, Yue Shu, Ming Zhang, Heber C. Nielsen, Clifford J. Rosen, Li Zeng
Summary: Our study reveals the unique glucose metabolism signatures of chondrocytes and their transition from glycolysis to oxidative phosphorylation as they mature. We also highlight the critical role of IGF2 in maintaining a balanced glucose metabolism and preventing excessive oxidative phosphorylation.
COMMUNICATIONS BIOLOGY
(2022)
Article
Electrochemistry
Jiawei Xu, Ke Yang, Xuezhong Zhang, Yunfeng Lei, Xiangyu Meng, Zhifei Wang
Summary: The research described a novel system composed of TiO2 and CeO2-CePO4 composite nanostructures to address the oxygen dependence issue in the first-generation amperometric glucose biosensors. The resulting composites showed good electro-catalytic activity towards glucose oxidation and provided a wide linear range for glucose detection, promising increased sensitivity of glucose biosensors.
JOURNAL OF SOLID STATE ELECTROCHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Teresa Hernandez-Gonzalez, Rocio Gonzalez-Barrio, Carolina Escobar, Juan Antonio Madrid, Maria Jesus Periago, Maria Carmen Collado, Frank A. J. L. Scheer, Marta Garaulet
Summary: The study found that consuming chocolate in the morning or in the evening/night had different effects on hunger and appetite, body weight, energy intake, substrate oxidation, fasting glucose, microbiota, and sleep rhythms.
Review
Oncology
Martina Dameri, Gabriella Cirmena, Francesco Ravera, Lorenzo Ferrando, Paola Cuccarolo, Mario Stabile, Giuseppe Nicolo Fanelli, Pier Vitale Nuzzo, Massimo Calabrese, Alberto Tagliafico, Alberto Ballestrero, Gabriele Zoppoli
Summary: Liquid biopsy has the potential to revolutionize clinical practice by offering a non-invasive approach for cancer diagnosis and treatment. However, the lack of standardized protocols for sample handling has hindered its implementation in clinical settings. This study provides a critical review of available standard operating procedures (SOPs) for liquid biopsy management and presents SOPs developed and utilized in a clinical trial. The aim is to address common issues and promote the adoption of interlaboratory shared protocols for optimized preanalytical handling of blood and urine samples.
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
(2023)
Article
Economics
Saman Eskandarzadeh, Behnam Fahimnia, Kai Hoberg
Summary: Complete and accurate data is crucial for effective supply chain decision making. However, human operators in charge of data entry tasks often do not comply with standard operating procedures (SOPs), leading to low-quality data. This study finds that an operator's workload, fatigue, and work experience directly impact compliance levels, and a company's intervention to reinforce compliance behavior can moderate these impacts.
TRANSPORTATION RESEARCH PART E-LOGISTICS AND TRANSPORTATION REVIEW
(2023)
Article
Sport Sciences
Maja Tomczyk, Zbigniew Jost, Maciej Chroboczek, Robert Urbanski, Philip C. Calder, Helena L. Fisk, Mateusz Sprengel, Jedrzej Antosiewicz
Summary: The study aimed to investigate the effects of 12 wk of omega-3 fatty acid supplementation during endurance training on omega-3 index (O3I) and indicators of running performance in amateur long-distance runners. The results showed a significant increase in O3I, improvements in (V) over dotO(2peak) and running economy, but no significant effect on the 1500-m run trial time.
MEDICINE & SCIENCE IN SPORTS & EXERCISE
(2023)
Article
Biochemistry & Molecular Biology
Carina A. Valenzuela, Ella J. Baker, Elizabeth A. Miles, Philip C. Calder
Summary: Conjugated linoleic acid (CLA) isomers, specifically cis-9, trans-11 (CLA9,11) and trans-10, cis-12 (CLA10,12), have shown modest anti-inflammatory effects on endothelial cells (ECs) at low concentrations. These CLAs decrease the concentrations of inflammatory factors such as MCP-1, IL-6, IL-8, and RANTES in the culture medium, but also upregulate some pro-inflammatory genes while downregulating others. The findings suggest that CLAs may have a role in preventing atherosclerosis by modulating inflammation in ECs.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Helen M. M. Lindqvist, Anna Winkvist, Inger Gjertsson, Philip C. C. Calder, Aaron M. M. Armando, Oswald Quehenberger, Roxana Coras, Monica Guma
Summary: A study on patients with rheumatoid arthritis found that consuming blue mussels, which are rich in n-3 fatty acids, led to significant changes in certain oxylipin levels, but did not have a noticeable impact on inflammation. Further research is needed to investigate the relationship between n-3 fatty acid intake, blood oxylipins, and inflammation.
Article
Nutrition & Dietetics
Benjamin Hess, Martin Cahenzli, Alastair Forbes, Rosa Burgos, Federico Coccolini, Olivier Corcos, Mette Holst, Oivind Irtun, Stanislaw Klek, Loris Pironi, Henrik Hojgaard Rasmussen, Mireille J. Serlie, Ronan Thibault, Simon Gabe, Annika Reintam Blaser
Summary: This survey assesses current attitudes and practices in managing acute mesenteric ischemia (AMI) worldwide. Results show that diagnosis of AMI is often delayed but rarely missed. Abdominopelvic CT-scan with intravenous contrast was suggested as the most useful diagnostic test. Treatment approaches vary greatly, indicating the need for updated guidelines.
CLINICAL NUTRITION ESPEN
(2023)
Article
Endocrinology & Metabolism
Ilse Vanhorebeek, Jan Gunst, Michael P. Casaer, Inge Derese, Sarah Derde, Lies Pauwels, Johan Segers, Greet Hermans, Rik Gosselink, Greet van den Berghe
Summary: This study investigated the impact of critical illness on muscular expression of irisin, kynurenine aminotransferases, and amylase, and their association with clinical outcomes, as well as the effects of interventions that attenuate muscle wasting/weakness. The findings showed that critically ill patients had lower mRNA expression levels of FNDC5, KYAT1, and amylase compared to controls. Lower expression of FNDC5 was associated with higher ICU mortality and ICU-acquired weakness, while lower amylase expression was associated with longer ICU stay. Lower KYAT1 expression was associated with a lower risk of weakness. The study also found that neuromuscular electrical stimulation increased FNDC5 expression and that late parenteral nutrition patients had higher KYAT1 expression compared to early parenteral nutrition patients.
JOURNAL OF THE ENDOCRINE SOCIETY
(2023)
Review
Nutrition & Dietetics
Alexandra W. C. Einerhand, Wiola Mi, Alfred Haandrikman, Xiao-Yang Sheng, Philip C. Calder
Summary: Linoleic acid and α-linolenic acid are essential fatty acids crucial for health. Levels of linoleic acid in breast milk and infant formula vary across countries, and this study aims to review the global levels of these fatty acids and their impact on infant formula health benefits based on published literature.
Article
Nutrition & Dietetics
Rianne Slingerland-Boot, Eveline Rooijakkers, Kristine Koekkoek, Dick van Blokland, Sesmu Arbous, Arthur van Zanten
Summary: This study evaluates the associations between macronutrient intake and clinical outcomes in ICU patients with refeeding hypophosphatemia. The results suggest that high protein intake during the first three days of ICU admission is associated with increased 6-month mortality.
CLINICAL NUTRITION ESPEN
(2023)
Article
Agricultural Economics & Policy
Ellen Dyson, Rachel Helbig, Tessa Avermaete, Kate Halliwell, Philip C. Calder, Lynn R. Brown, John Ingram, Bert Popping, Hans Verhagen, Alan R. Boobis, Isabelle Guelinckx, Louise Dye, Neil Boyle
Summary: The reverberations of the Ukraine-Russia conflict have had a profound global impact in 2022, exacerbating existing pressures on global systems. The vulnerabilities of the global food system have been exposed, resulting in disruptions to food supply chains and disproportionately affecting vulnerable populations in the Global South.
Article
Nutrition & Dietetics
Noora Houttu, Tero Vahlberg, Elizabeth A. Miles, Philip C. Calder, Kirsi Laitinen
Summary: This study investigates the impact of fish oil and probiotics on serum fatty acids in pregnant women, as well as the relationship between fatty acids, low-grade inflammation, and gestational diabetes mellitus (GDM). The results show that pregnant women who consume fish oil and/or probiotics have higher levels of n-3 long-chain PUFA (LC-PUFA) in their serum, but these fatty acids are negatively correlated with low-grade inflammation and positively correlated with the risk of GDM.
BRITISH JOURNAL OF NUTRITION
(2023)
Article
Nutrition & Dietetics
Pierre Singer, Annika Reintam Blaser, Mette M. Berger, Philip C. Calder, Michael Casaer, Michael Hiesmayr, Konstantin Mayer, Juan Carlos Montejo-Gonzalez, Claude Pichard, Jean -Charles Preiser, Wojciech Szczeklik, Arthur R. H. van Zanten, Stephan C. Bischoff
Summary: Following the new ESPEN Standard Operating Procedures, the previous 2019 guideline on medical nutrition therapy for critically ill patients has been shortened and partially revised. This publication proposes a practical guideline based on the published scientific guideline, but with shortened and illustrated flow charts. The main goal of this practical guideline is to increase understanding and facilitate implementation of Nutrition in the ICU guidelines, including all items discussed in the previous guidelines and special conditions.
CLINICAL NUTRITION
(2023)
Review
Critical Care Medicine
Jan Gunst, Michael. P. P. Casaer, Jean-Charles Preiser, Jean Reignier, Greet van den Berghe
Summary: Recent randomized controlled trials have shown that early full nutritional support does not benefit critically ill patients and may cause harm. The absence of benefit may not be due to low nutritional risk patients or low amino acid doses, as previously hypothesized. Mechanistic studies suggest that the lack of benefit is due to anabolic resistance and suppression of recovery-enhancing pathways induced by feeding. Large randomized controlled trials have not investigated the impact of different feeding strategies initiated after the acute phase in patients recovering from critical illness.
Review
Nutrition & Dietetics
Maja Tomczyk, Jeffery L. Heileson, Miroslaw Babiarz, Philip C. Calder
Summary: Fatty fish and certain species of algae are the only natural sources of EPA and DHA, which have various beneficial effects for athletes. Due to limited intake and fluctuating content, athletes may consider using supplements to ensure sufficient EPA and DHA levels.
Review
Nutrition & Dietetics
Philip C. Calder, Anna Bach-Faig, Teresa Bevacqua, Chrystopherson Gengyny Caballero Lopez, Zheng-Yu Chen, Daragh Connolly, Wan Lee Koay, Simin N. Meydani, Ari-Sentug Pinar, Durval Ribas-Filho, Adeline Pierre
Summary: Self-care is important for improving health and social well-being. Understanding how the body works and how to keep it healthy is crucial. The immune system plays a vital role in defending against pathogens and maintaining overall health. Active management of the immune system is necessary to reduce the risk of chronic diseases. A healthy and diverse diet, along with regular exercise, adequate sleep, and mental resilience, is key to supporting immune function.
BMJ NUTRITION, PREVENTION & HEALTH
(2023)
Article
Critical Care Medicine
Bethan Jenkins, Philip C. Calder, Luise Marino
Summary: This study surveyed the current practice of enteral feeding and gastric residual volume (GRV) monitoring in UK adult ICUs, and described the impact of GRV monitoring on enteral feeding. The results showed that despite the poor validity of GRV measurement, it is still commonly used in UK adult ICUs to assess enteral feeding intolerance. This suggests the need for further research on the benefits of ongoing GRV measurements and alternative markers of enteral feeding intolerance in the adult ICU population.
JOURNAL OF THE INTENSIVE CARE SOCIETY
(2023)
Article
Nutrition & Dietetics
Max Melchers, Anoek Jacqueline Hubertine Hermans, Suzanne Belia Hulsen, Imre Willemijn Kehinde Kouw, Arthur Raymond Hubert van Zanten
Summary: This study highlights the importance of providing adequate nutritional therapy to COVID-19 patients in the ICU who require invasive mechanical ventilation. Meeting over 80% of the protein goals based on BIA-derived FFM was associated with lower mortality rates.
CLINICAL NUTRITION
(2023)
