Article
Immunology
Damien C. Tully, Judith A. Hahn, David J. Bean, Jennifer L. Evans, Meghan D. Morris, Kimberly Page, Todd M. Allen
Summary: Deep sequencing of hepatitis C virus (HCV) among self-described injecting partnerships showed that the majority of transmission events originate from outside of the injecting partnership, and the direction of transmission is often difficult to accurately infer, especially in high-risk networks with rapid transmission events.
CLINICAL INFECTIOUS DISEASES
(2022)
Article
Public, Environmental & Occupational Health
Stacy R. Tressler, Maria C. del Rosario, Michelle D. Kirby, Ashley N. Simmons, Melissa A. Scott, Sherif Ibrahim, Joseph C. Forbi, Hong Thai, Guo-liang Xia, Meghan Lyman, Melissa G. Collier, Priti R. Patel, Danae Bixler
Summary: An outbreak of 7 HCV and 4 HBV cases occurred in a cardiology clinic, likely due to breaches in injection safety. Following investigation and switching to single-dose medications, no further cases were identified, indicating successful control of the outbreak.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2021)
Review
Pharmacology & Pharmacy
Mario Enrico Canonico, Giuseppe Damiano Sanna, Roberta Siciliano, Fernando Scudiero, Giovanni Esposito, Guido Parodi
Summary: HCV infection increases cardiovascular and bleeding risks, requiring concomitant use of antithrombotic therapies. However, there may be drug-drug interactions between antithrombotic drugs and HCV antiviral drugs.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Infectious Diseases
Hongyu Chen, Jianxiang Liu, Qian Kang, Hao Luo, Ning Tan, Jiali Pan, Yuqing Yang, Min Yu, Dan Liu, Hongli Xi, Yifan Han, Ran Cheng, Yanyan Yu, Xiaoyuan Xu
Summary: This study found that the HCV genotype has a limited impact on the presence of five RASs, while there is a correlation between HCV RNA and HCV cAg. The appearance of certain RASs does not have a significant effect on DAA treatment in patients with chronic hepatitis C.
INFECTION AND DRUG RESISTANCE
(2022)
Review
Chemistry, Analytical
Vigneswaran Narayanamurthy, Z. E. Jeroish, K. S. Bhuvaneshwari, Fahmi Samsuri
Summary: Proper diagnosis is essential in avoiding disease consequences, especially for severe issues like hepatitis C virus (HCV) that can cause significant damage to the liver. Developing strategies for appropriate selection of POCT for HCV detection, initiating proper antiviral therapy, and defining associated risks is critical for achieving optimal outcomes. Alternative strategies are needed to enhance HCV diagnosis, with molecular assays being precise but requiring additional approaches for infected populations to improve detection.
ANALYTICAL METHODS
(2021)
Article
Immunology
Pei-Yuan Wu, Min-Nan Hung, Wei-Lun Huang, Jyh-Yuan Yang, Chia-ping Su
Summary: The investigation into hepatitis C virus (HCV) infection in a respiratory care ward found that the infection was associated with frequent injections and infection control lapses. Initiating safe injection practices and reducing injection frequency are suggested to prevent HCV transmission in healthcare settings.
JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION
(2021)
Article
Multidisciplinary Sciences
Trang Nguyen Hoa, Saif Ullah Munshi, Khanh Nguyen Ngoc, Chau Le Ngoc, Thanh Tran Thi Thanh, Tahmina Akther, Shahina Tabassum, Nilufa Parvin, Stephen Baker, Motiur Rahman
Summary: HEV infection in Bangladesh is primarily caused by genotype 1a strains, which are associated with both endemic and outbreak cases. Virulence associated mutations are prevalent in Bangladeshi HEV isolates, with alterations in antigenicity observed in both B and T cell epitopes.
Article
Computer Science, Interdisciplinary Applications
Fabio Polisano, Andrea Dan Ryals, Gabriele Pannocchia, Alberto Landi
Summary: This study proposes a strategy to optimize hepatitis C treatment using model predictive control, which successfully reduces treatment costs while maintaining good pharmacological control. The results demonstrate the feasibility and effectiveness of this approach.
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
(2021)
Article
Gastroenterology & Hepatology
Vanessa Koo, Feng Tian, William W. L. Wong
Summary: HCV point-of-care testing is cost-effective for injection drug users, as it can prolong individuals' lifespan and save healthcare costs associated with HCV-related complications.
LIVER INTERNATIONAL
(2022)
Article
Immunology
Kate Shapiro, Shane J. Cross, Ted H. Morton, Hiroto Inaba, Ashley Holland, Francisca R. Fasipe, Elisabeth E. Adderson
Summary: This article summarizes a case of catheter-related M. neoaurum bacteremia in a child with leukemia and 36 previously reported cases of M. neoaurum infection. Most infections occurred in young to middle-aged adults with serious underlying medical conditions and commonly involved medical devices. Overall, infections were generally not severe and responded well to treatment.
EMERGING INFECTIOUS DISEASES
(2023)
Article
Immunology
Pierre Cappy, Quentin Lucas, Nakourogou Kankarafou, Camille Sureau, Syria Laperche
Summary: Following a study demonstrating the role of hepatitis C virus (HCV) in transmitting hepatitis D virus (HDV) in a liver-humanized mouse model, a large cohort of HCV-positive blood donors were screened for HDV markers. However, no evidence of HCV-assisted propagation of HDV in humans was found.
JOURNAL OF INFECTIOUS DISEASES
(2021)
Article
Immunology
Ana Carrero, Juan Berenguer, Victor Hontanon, Josep M. Guardiola, Jordi Navarro, Miguel A. von Wichmann, Maria J. Tellez, Carmen Quereda, Ignacio Santos, Jose Sanz, Maria J. Galindo, Jose Hernandez-Quero, Maria A. Jimenez-Sousa, Leire Perez-Latorre, Jose M. Bellon, Salvador Resino, Herminia Esteban, Esteban Martinez, Juan Gonzalez-Garcia
Summary: Eradication of HCV did not lead to significant changes in BMD or biomarkers of bone remodeling in HIV/HCV-coinfected individuals.
CLINICAL INFECTIOUS DISEASES
(2021)
Review
Virology
Carlos Garcia-Crespo, Isabel Gallego, Maria Eugenia Soria, Ana Isabel de Avila, Brenda Martinez-Gonzalez, Lucia Vazquez-Sirvent, Rebeca Lobo-Vega, Elena Moreno, Jordi Gomez, Carlos Briones, Josep Gregori, Josep Quer, Esteban Domingo, Celia Perales
Summary: The replication of RNA viruses involves exploring sequence space to adapt to changing environments. Research on hepatitis C virus (HCV) has shown that despite prolonged replication, viral clones continue to expand in sequence space. The study suggests that HCV populations exhibit a permanent state of disequilibrium, potentially facilitating the finding of alternative mutational pathways for antiviral resistance.
Article
Biochemistry & Molecular Biology
Nagi M. El-Shafai, Shaymaa Shawky, Ibrahim M. El-Mehasseb, Maged A. El-Kemary
Summary: The research focused on the application of sandwich nanohybrid of nano-PVA and nano-chitosan in water treatment and drug adsorption, revealing their potential effects through tests on photocatalytic activity and release efficiency. Additionally, studies on cytotoxicity and antioxidant properties were conducted.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Medicine, General & Internal
Haneen Obeidat, Ziad El-nasser, Zouhair Amarin, Almutazballah Qablan, Faris Gharaibeh
Summary: This study aimed to assess the impact of the COVID-19 pandemic on infection rates among ICU patients and profile the drug resistance rates nationally. It included 589 COVID-19 patients, of whom 20% developed bacterial associated infections. Gram-negative bacteria like Acinetobacter baumannii and Eschericia coli were the most common isolated species, and they exhibited high levels of antibiotic resistance.
Article
Food Science & Technology
Steffany J. Cavallo, Elizabeth R. Daly, John Seiferth, Alisha M. Nadeau, Jennifer Mahoney, Jayne Finnigan, Peter Wikoff, Craig A. Kiebler, Latoya Simmons
FOODBORNE PATHOGENS AND DISEASE
(2015)
Article
Public, Environmental & Occupational Health
Elizabeth R. Daly, Jeanne P. Herrick, Elizabeth X. Maynard, Jose T. Montero, Christine Adamski, Jodie Dionne-Odom, Elizabeth A. Talbot, Sharon Alroy-Preis
PUBLIC HEALTH REPORTS
(2015)
Article
Public, Environmental & Occupational Health
Abigail A. Mathewson, Elizabeth R. Daly, Steffany J. Cavallo, Adnela Alic
DISASTER MEDICINE AND PUBLIC HEALTH PREPAREDNESS
(2015)
Article
Ophthalmology
Edmund Tsui, Erin Fogel, Katrina Hansen, Elizabeth A. Talbot, Roza Tammer, Jessa Fogel, Elizabeth R. Daly, James Noble, Lynda Caine, Michael E. Zegans
Article
Public, Environmental & Occupational Health
Elizabeth R. Daly, Kenneth Dufault, David J. Swenson, Paul Lakevicius, Erin Metcalf, Benjamin P. Chan
PUBLIC HEALTH REPORTS
(2017)
Article
Public, Environmental & Occupational Health
E. R. Daly, C. Fredette, A. A. Mathewson, K. Dufault, D. J. Swenson, B. P. Chan
ZOONOSES AND PUBLIC HEALTH
(2017)
Article
Public, Environmental & Occupational Health
Elizabeth R. Daly, Benjamin P. Chan, Elizabeth A. Talbot, Julianne Nassif, Christine Bean, Steffany J. Cavallo, Erin Metcalf, Karen Simone, Alan D. Woolf
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
(2018)
Review
Public, Environmental & Occupational Health
Elizabeth R. Daly
Summary: Applied epidemiologists play a crucial role in the public health workforce and need to develop new skills to meet the evolving needs of public health. A review of the literature identified a number of studies describing the functions and training needs of epidemiologists, but there is a lack of research assessing their competency. Continued assessment of the workforce literature is recommended to inform effective workforce development activities.
ANNALS OF EPIDEMIOLOGY
(2021)
Article
Public, Environmental & Occupational Health
Elizabeth R. Daly, Jessica Arrazola, Karl Umble
Summary: This study investigated the use of epidemiology job classifications, career ladders, and professional competencies in state health departments in the United States. The results showed that most state health departments have specific job classifications and career ladders for epidemiologists, which were believed to positively contribute to recruitment and retention of epidemiologists. However, only a minority of state epidemiologists used applied epidemiology competencies to develop career ladders.
JOURNAL OF PUBLIC HEALTH MANAGEMENT AND PRACTICE
(2022)
Article
Immunology
Taylor D. Selembo, Elizabeth A. Talbot, Christophe T. Courtine, Elizabeth R. Daly, Torane W. Hull, Kirsten J. Durzy
Summary: The global COVID-19 pandemic has worsened social vulnerabilities and racial disparities, leading to disproportionate morbidity and mortality. The State of New Hampshire developed a transparent framework for vaccine allocation, allocating 10% of the supply to disproportionately impacted and highly vulnerable populations.
Article
Public, Environmental & Occupational Health
Elizabeth R. Daly, Jessica Arrazola, Karl Umble
Summary: This research study examines the role and readiness of state health department epidemiologists in the United States to work in emerging areas of public health practice. The findings highlight the importance of epidemiologists in these areas and suggest strategies to facilitate their engagement.
JOURNAL OF PUBLIC HEALTH MANAGEMENT AND PRACTICE
(2022)
Article
Public, Environmental & Occupational Health
Elizabeth R. Daly, Moriah Gendelman, Jessica Arrazola, Katie Sellers
Summary: The research aimed to identify the training needs and awareness of emerging areas of public health practice (EAoP) among state health agency central office (SHA-CO) epidemiologists. The results showed that systems and strategic thinking, as well as budget and financial management, were the areas with the greatest training needs. Furthermore, participants with more years of work experience reported fewer skill gaps in most skill domains.
JOURNAL OF PUBLIC HEALTH MANAGEMENT AND PRACTICE
(2022)
Article
Public, Environmental & Occupational Health
Jessica Arrazola, Nancy Binkin, Maria Israel, Aaron Fleischauer, Elizabeth R. Daly, Robert Harrison, Jeffrey Engel
MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT
(2018)
Article
Immunology
Benjamin P. Chan, Elizabeth R. Daly, Elizabeth A. Talbot
EMERGING INFECTIOUS DISEASES
(2015)