Cytochrome P450 genotype-guided drug therapies: An update on current states

Effect of Genotype-Guided Warfarin Dosing on Clinical Events and Anticoagulation Control Among Patients Undergoing Hip or Knee Arthroplasty

(2017) Brian F. Gage et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Effect of carboxylesterase 1 S75N on clopidogrel therapy among acute coronary syndrome patients

(2017) Fei-Yan Xiao et al.   Scientific Reports

Cytochrome P450 CYP 2C19*2 Associated with Adverse 1-Year Cardiovascular Events in Patients with Acute Coronary Syndrome

(2015) You-quan Wei et al.   PLoS One

The effects of CES1A2 A(−816)C and CYP2C19 loss-of-function polymorphisms on clopidogrel response variability among Chinese patients with coronary heart disease

(2014) Cheng Xie et al.   Pharmacogenetics and Genomics

Understanding and preventing drug–drug and drug–gene interactions

(2014) Cara Tannenbaum et al.   Expert Review of Clinical Pharmacology

Clinical Pharmacogenetics Implementation Consortium Guidelines for CYP2C19 Genotype and Clopidogrel Therapy: 2013 Update

(2013) S A Scott et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Implementing genomic medicine in the clinic: the future is here

(2013) Teri A. Manolio et al.   GENETICS IN MEDICINE

A Pharmacogenetic versus a Clinical Algorithm for Warfarin Dosing

(2013) Stephen E. Kimmel et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Randomized Trial of Genotype-Guided Dosing of Warfarin

(2013) Munir Pirmohamed et al.   NEW ENGLAND JOURNAL OF MEDICINE

Effects of CYP2C19 Loss-of-Function Variants on the Eradication of H. pylori Infection in Patients Treated with Proton Pump Inhibitor-Based Triple Therapy Regimens: A Meta-Analysis of Randomized Clinical Trials

(2013) Hui-Lin Tang et al.   PLoS One

The functional G143E variant of carboxylesterase 1 is associated with increased clopidogrel active metabolite levels and greater clopidogrel response

(2012) Joshua P. Lewis et al.   Pharmacogenetics and Genomics

Pharmacogenetics: From Bench to Byte— An Update of Guidelines

(2011) J J Swen et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

2011 ACCF/AHA/SCAI Guideline for Percutaneous Coronary Intervention

(2011) Glenn N. Levine et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Emergency Hospitalizations for Adverse Drug Events in Older Americans

(2011) Daniel S. Budnitz et al.   NEW ENGLAND JOURNAL OF MEDICINE

ACCF/AHA Clopidogrel Clinical Alert: Approaches to the FDA “Boxed Warning”

(2010) David R. Holmes et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

VKORC1 Pharmacogenomics Summary

(2010) Ryan P. Owen et al.   Pharmacogenetics and Genomics

The Biochemistry of Drug Metabolism - An Introduction

(2009) Stefanie D. Krämer et al.   CHEMISTRY & BIODIVERSITY

Proton Pump Inhibitors

(2009) Kwong Ming Fock et al.   CLINICAL PHARMACOKINETICS

Identification of New CYP2C19 Variants Exhibiting Decreased Enzyme Activity in the Metabolism of S-Mephenytoin and Omeprazole

(2009) S.-J. Lee et al.   DRUG METABOLISM AND DISPOSITION

Identification of the Human Cytochrome P450 Enzymes Involved in the Two Oxidative Steps in the Bioactivation of Clopidogrel to Its Pharmacologically Active Metabolite

(2009) M. Kazui et al.   DRUG METABOLISM AND DISPOSITION

Association of Cytochrome P450 2C19 Genotype With the Antiplatelet Effect and Clinical Efficacy of Clopidogrel Therapy

(2009) Alan R. Shuldiner   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Ticagrelor versus Clopidogrel in Patients with Acute Coronary Syndromes

(2009) Lars Wallentin et al.   NEW ENGLAND JOURNAL OF MEDICINE

Influence of the CYP2D6*4 polymorphism on dose, switching and discontinuation of antidepressants

(2008) Monique J. Bijl et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

The Effect of CYP2C19 Polymorphism on the Pharmacokinetics and Pharmacodynamics of Clopidogrel: A Possible Mechanism for Clopidogrel Resistance

(2008) KA Kim et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Activation of the Antiviral Prodrug Oseltamivir Is Impaired by Two Newly Identified Carboxylesterase 1 Variants

(2008) H.-J. Zhu et al.   DRUG METABOLISM AND DISPOSITION

Cytochrome P450 2C19 polymorphism in young patients treated with clopidogrel after myocardial infarction: a cohort study

(2008) Jean-Philippe Collet et al.   LANCET

Cytochrome P-450 Polymorphisms and Response to Clopidogrel

(2008) Jessica L. Mega et al.   NEW ENGLAND JOURNAL OF MEDICINE

The future (or lack of future) of personalized prescription in psychiatry

(2008) Jose de Leon   PHARMACOLOGICAL RESEARCH