Article
Medicine, General & Internal
Antonio Queiros, Ana Amorim-de-Sousa, Paulo Fernandes, Maria Sameiro Ribeiro-Queiros, Cesar Villa-Collar, Jose M. Gonzalez-Meijome
Summary: This study aims to evaluate and develop mathematical models for estimating axial length (AL) in a cross-sectional and longitudinal sample. The existing mathematical equation proposed by Morgan was found to have statistically significant differences in AL estimation based on gender, ametropia, type of astigmatism, and age. A new mathematical model was proposed and tested, showing no statistically significant differences in axial length estimation between the models in a longitudinal sample. Despite errors in predicted axial length values, the mathematical equations are valid for estimating differences in axial increment for ages between 9 and 24 years.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Ophthalmology
Shang Liu, Xiangui He, Jingjing Wang, Linlin Du, Hui Xie, Jinliuxing Yang, Kun Liu, Haidong Zou, Xun Xu, Jun Chen
Summary: This study investigates the association between axial length elongation and spherical equivalent progression in children and adolescents. The results indicate that this association is influenced by age and refractive status.
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2022)
Article
Medicine, General & Internal
Huailin Zhu, Changyang Liu, Mingjun Gao, Siqi Zhang, Lan Zhang, Qi Zhao
Summary: This study analyzed the relationship between diopter and choroidal thickness in myopic children and found significant differences in choroidal thickness among myopic children. Choroidal thickness was positively correlated with diopter and negatively correlated with axial length. Therefore, choroidal thickness is considered an important indicator for evaluating the progression of myopia.
FRONTIERS IN MEDICINE
(2023)
Article
Ophthalmology
Shaojun Zhu, Haodong Zhan, Zhipeng Yan, Maonian Wu, Bo Zheng, Shanshan Xu, Qin Jiang, Weihua Yang
Summary: This study used machine learning methods to predict the changes in spherical equivalent refraction (SER) and axial length (AL) in children. The results showed that different models performed best in predicting SER and AL at different grade levels.
INDIAN JOURNAL OF OPHTHALMOLOGY
(2023)
Article
Ophthalmology
Shaojun Zhu, Haodong Zhan, Zhipeng Yan, Maonian Wu, Bo Zheng, Shanshan Xu, Qin Jiang, Weihua Yang
Summary: This study used machine learning methods to predict changes in spherical equivalent refraction and axial length in children. The results showed that the orthogonal matching pursuit algorithm performed the best in predicting spherical equivalent refraction, while the kernel ridge and multilayer perceptron algorithms performed the best in predicting axial length in most experiments.
INDIAN JOURNAL OF OPHTHALMOLOGY
(2023)
Article
Neurosciences
Shuxian Zhang, Hui Zhang, Lihua Li, Xiaoyan Yang, Shumao Li, Xuan Li
Summary: This study found that the decentration of the treatment zone of orthokeratology lenses affects the axial length growth in adolescents. The greater the decentration, the slower the axial length growth.
FRONTIERS IN NEUROSCIENCE
(2022)
Review
Ophthalmology
Yoo Jin Kim, Tae Gi Kim
Summary: This study investigated emmetropic non-cycloplegic refraction (NCR) in children and compared the difference in progression between children with emmetropic and hyperopic cycloplegic refraction (CR) values over 2 years. The results showed that even if NCR showed emmetropia, children with baseline CR values of emmetropia showed greater progression. Cycloplegia is essential to confirm the correct refractive status in children and may be useful for predicting prognosis.
Article
Public, Environmental & Occupational Health
Wenjing Wang, Shuzhen Peng, Faxue Zhang, Boya Zhu, Longjiang Zhang, Xiaodong Tan
Summary: This study investigated the changes in vision among children before and after the COVID-19 pandemic. It found an increase in myopia prevalence among younger children, but slight improvement in vision in 2021. These results suggest the need to focus on vision prevention and control in preschool-aged children even after the pandemic.
INTERNATIONAL JOURNAL OF PUBLIC HEALTH
(2022)
Article
Ophthalmology
Niklas Cyril Hansen, Anders Hvid-Hansen, Flemming Moller, Toke Bek, Dorte Ancher Larsen, Nina Jacobsen, Line Kessel
Summary: Low-dose atropine eye drops showed efficacy in reducing myopia progression in Danish children and demonstrated a good safety profile.
Review
Medicine, General & Internal
Hou-Ren Tsai, Tai-Li Chen, Jen-Hung Wang, Huei-Kai Huang, Cheng-Jen Chiu
Summary: This study investigated the efficacy and safety of 0.01% atropine in slowing axial elongation in children with myopia, finding that it significantly slowed the progression of refraction and axial length over a 1-year period with no significant adverse effects.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Pediatrics
Jingfeng Mu, Dan Zeng, Jingjie Fan, Meizhou Liu, Haoxi Zhong, Xinyi Shuai, Shaochong Zhang
Summary: This study aimed to assess the association between axial length/corneal radius ratio (AL/CR ratio), axial length (AL), and refractive status, and evaluate their accuracy for myopia assessment in Chinese children. The results suggested that the AL/CR ratio may be an alternative indicator for myopia assessment in children, and combining demographic factors with the AL/CR ratio can improve the accuracy of the assessment.
FRONTIERS IN PEDIATRICS
(2022)
Article
Medicine, General & Internal
Erisa Yotsukura, Hidemasa Torii, Hiroko Ozawa, Richard Yudi Hida, Tetsuro Shiraishi, Ivan Corso Teixeira, Yessa Vervloet Bertollo Lamego Rautha, Caio Felipe Moraes do Nascimento, Kiwako Mori, Miki Uchino, Toshihide Kurihara, Kazuno Negishi, Kazuo Tsubota
Summary: The study evaluated the prevalence of myopia and the light environment in Aracati, Brazil, finding the mean spherical equivalent and axial length, as well as the prevalence of myopia and high myopia among schoolchildren in the region. Lifestyle factors were not associated with myopia, but the light environment may have an impact on axial length and refractive errors.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Medicine, General & Internal
Kiwako Mori, Hidemasa Torii, Yutaka Hara, Michiko Hara, Erisa Yotsukura, Akiko Hanyuda, Kazuno Negishi, Toshihide Kurihara, Kazuo Tsubota
Summary: The study found through a double-blinded randomized clinical trial that violet light-transmitting eyeglasses (VL glasses) have a suppressive effect on myopia in children, particularly in those with shorter near-work time and those who had never worn eyeglasses before the trial. The axial elongation suppressive rate in the VL glasses group was 21.4% over two years.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Ophthalmology
Snigdha Sen, Himanshu Yadav, Anu Jain, Sadhna Verma, Preeti Gupta
Summary: This study aimed to investigate the effect of atropine 0.01% eye drops on myopia progression in children aged over 5 years. The results showed a significant difference in axial length and refraction increase between the treatment and placebo groups after a two-year follow-up.
INDIAN JOURNAL OF OPHTHALMOLOGY
(2022)
Article
Biotechnology & Applied Microbiology
Qi Ren, Zhe Chu, Wei Cui, Lu Cheng, Wenjie Su, Hao Cheng, Jie Wu
Summary: The purpose of this study was to investigate the relationship between the corneal material stiffness parameter stress-strain index (SSI) and axial length (AL) elongation in varying severities of myopia using a mathematical estimation model. The study included data from healthy subjects and patients preparing for refractive surgery. The results showed that the severity of myopia was negatively correlated with the corneal stiffness index (SSI), while AL showed a positive correlation with SSI.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Ophthalmology
Peiyao Jin, Haidong Zou, Xun Xu, Ta Chen Chang, Jianfeng Zhu, Junjie Deng, Minzhi Lv, Jiali Jin, Sifei Sun, Ling Wang, Xiangui He
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
(2019)
Article
Ophthalmology
Wenwen Xue, Ming-ming Zhu, Bi-jun Zhu, Jian-nan Huang, Qian Sun, Yu-yu Miao, Hai-dong Zou
INTERNATIONAL OPHTHALMOLOGY
(2019)
Article
Ophthalmology
Wenwen Xue, Xian Xu, Haidong Zou
INTERNATIONAL OPHTHALMOLOGY
(2019)
Article
Ophthalmology
Junjie Deng, Jiali Jin, Minzhi Lv, Wenhan Jiang, Sifei Sun, Chunxia Yao, Jianfeng Zhu, Haidong Zou, Ling Wang, Xiangui He, Xun Xu
ACTA OPHTHALMOLOGICA
(2019)
Article
Ophthalmology
Xiangui He, Padmaja Sankaridurg, Shuyu Xiong, Wayne Li, Bo Zhang, Rebecca Weng, Jianfeng Zhu, Thomas Naduvilath, Serge Resnikoff, Haidong Zou, Xun Xu
CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
(2019)
Review
Ophthalmology
Divya Jagadeesh, Krupa Philip, Thomas J. Naduvilath, Cathleen Fedtke, Monica Jong, Haidong Zou, Padmaja Sankaridurg
CLINICAL AND EXPERIMENTAL OPTOMETRY
(2019)
Article
Ophthalmology
Ying Xiao, Tao Li, Yan Jia, Shanshan Wang, Chenhao Yang, Haidong Zou
JOURNAL OF OPHTHALMOLOGY
(2019)
Article
Chemistry, Analytical
Huiyi Jin, Bijun Zhu, Xia Liu, Jing Jin, Haidong Zou
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2019)
Article
Ophthalmology
Yingyan Ma, Senlin Lin, Ian G. Morgan, Jos J. Rozema, Rafael Iribarren, Jianfeng Zhu, Rong Zhao, Bo Zhang, Yao Yin, Yueqin Shao, Xiangui He, Xun Xu, Haidong Zou
Summary: In preschool children, changes in refraction and refractive components over one year were observed. Loss of lens power in eyes with lower baseline spherical equivalent refraction resulted in hyperopic shifts, while in eyes with higher baseline spherical equivalent refraction, the loss of lens power compared to axial elongation was reduced, leading to myopic shifts. This study highlighted the homeostasis of human refraction and how it leads to a preferred state of mild hyperopia.
ACTA OPHTHALMOLOGICA
(2021)
Article
Medicine, General & Internal
Yingyan Ma, Senlin Lin, Liping Li, Yingnan Jia, Haidong Zou
Summary: The study showed that economic development in China is positively associated with urban environment, Gini coefficient of property, logarithm of average property, average education duration, and return-to-education rate, all of which are positively associated with the logit function of visual impairment rate among students.
Article
Medicine, General & Internal
Xiangui He, Padmaja Sankaridurg, Shuyu Xiong, Wayne Li, Thomas Naduvilath, Senlin Lin, Rebecca Weng, Minzhi Lv, Yingyan Ma, Lina Lu, Jingjing Wang, Rong Zhao, Serge Resnikoff, Jianfeng Zhu, Haidong Zou, Xun Xu
Summary: The study reported on the prevalence of myopia and high myopia among children aged 4-14 in Shanghai, as well as the impact of education on their spherical equivalent refractive error. The findings showed that myopia was associated with education, primarily focused on near-based activities. Efforts to reduce the burden of myopia should be directed towards public awareness, educational reform, and improvements in the healthcare system.
Article
Chemistry, Analytical
Tengfei Long, Yi Xu, Haidong Zou, Lina Lu, Tianyi Yuan, Zhou Dong, Jiqun Dong, Xin Ke, Saiguang Ling, Yingyan Ma
Summary: Pixel pitch calibration is crucial for quantitative measurement of fundus structures in fundus images. This proposed method, based on automated ROI and optic disc detection, allows for estimation of pixel pitch without specific parameters or chess board images.
Review
Biochemistry & Molecular Biology
Yiwei Wu, Haidong Zou
Summary: Diabetic retinopathy is a significant complication of diabetes that can result in blindness. Mitochondria, the energy-producing organelles, play a crucial role in cellular metabolism and function. Under high glucose conditions, metabolic changes and epigenetic alterations in mitochondria-related genes can cause mitochondrial dysfunction and apoptosis. Additionally, mitophagy and mitochondrial dynamics also adaptively change. These mechanisms are likely to contribute to the development and progression of diabetic retinopathy and provide insights for its prevention and treatment.
Article
Public, Environmental & Occupational Health
Senlin Lin, Yingyan Ma, Yi Xu, Lina Lu, Jiangnan He, Jianfeng Zhu, Yajun Peng, Tao Yu, Nathan Congdon, Haidong Zou
Summary: This study compares the cost-effectiveness of an artificial intelligence (AI) model with manual grading in community-based telemedicine screening for diabetic retinopathy. The results show that in low-income countries, replacing manual grading with an AI model does not improve screening outcomes due to lower labor costs and minimal savings in healthcare expenditures.
JMIR PUBLIC HEALTH AND SURVEILLANCE
(2023)
Article
Ophthalmology
Wen-Wen Xue, Pei Zhang, Hai-Dong Zou
INTERNATIONAL JOURNAL OF OPHTHALMOLOGY
(2019)