Article
Multidisciplinary Sciences
Kouji Narita, Krisana Asano, Kyosuke Yamane, Hiroyuki Ohashi, Tatsushi Igarashi, Akio Nakane
Summary: This study reported the germicidal effect of 222 nm UVC and the critical role of bandpass filters in reducing the harmful effects of wavelengths outside of 222 nm on mammalian cells. Mice exposed to UVC emitted from a filtered lamp showed significantly lower levels of DNA damage compared to those exposed to UVC emitted from an unfiltered lamp.
Article
Agriculture, Dairy & Animal Science
Shuang Li, Wenjuan Sun, Kai Zhang, Jiawei Zhu, Xueting Jia, Xiaoqing Guo, Qingyu Zhao, Chaohua Tang, Jingdong Yin, Junmin Zhang
Summary: This study established a Se-deficient pig model and found that Se deficiency induces spleen injury through regulation of selenoproteins, oxidative stress, inflammation, and apoptosis. The findings showed decreased erythroid parameters, increased osmotic fragility of erythrocytes, altered spleen structure, and splenocyte apoptosis in response to Se deficiency.
JOURNAL OF ANIMAL SCIENCE AND BIOTECHNOLOGY
(2021)
Article
Food Science & Technology
Chaohua Tang, Shuang Li, Kai Zhang, Jing Li, Yunsheng Han, Qingyu Zhao, Xiaoqing Guo, Yuchang Qin, Jingdong Yin, Junmin Zhang
Summary: A study using a pig model investigates the effects of selenium deficiency on the heart. The study reveals that selenium deficiency leads to cardiac oxidative stress, disordered energy production, lipid metabolic vulnerabilities, and inflammation initiation pathways. These findings provide potential targets for treating cardiac diseases induced by redox imbalance.
MOLECULAR NUTRITION & FOOD RESEARCH
(2022)
Article
Engineering, Environmental
Yanping Zhao, Ruxia Qiao, Siyuan Zhang, Guoxiang Wang
Summary: The study found that microplastic fibers can cause intestinal damage and toxicity in zebrafish, with longer fibers producing more serious effects. Metabolomics analysis revealed that microplastic fibers can up-regulate glycerophospholipids metabolism, exacerbating oxidative damage and inflammation, while down-regulating fatty acyls metabolism related to nutritional deficiency.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Environmental Sciences
Kultigin Cavusoglu, Tugce Kalefetoglu Macar, Oksal Macar, Dilek Cavusoglu, Emine Yalcin
Summary: This study aimed to evaluate the damages caused by ultraviolet (UV) radiation on Allium cepa L. roots. The research found that UV exposure resulted in growth inhibition, cytogenotoxicity, oxidative stress, and anatomical damages. The damages were more severe in cells treated with UV-C compared to UV-A.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Reproductive Biology
Xue-Wei Chen, Jia-Hong Chu, Lan-Xin Li, Pei-Chao Gao, Zhen-Yong Wang, Rui-Feng Fan
Summary: Selenium effectively alleviates HgCl2-induced testicular injury in chickens by enhancing antioxidant capacity and reducing inflammation.
Article
Biochemistry & Molecular Biology
Jana Jandova, Jeremy Snell, Anh Hua, Sally Dickinson, Jocelyn Fimbres, Georg T. Wondrak
Summary: The study focuses on the stress response induced by hypochlorous acid (HOCl) in the skin and its combination effects with solar ultraviolet (UV) radiation, showing that HOCl can inhibit UV-induced skin inflammation, potentially contributing to the treatment of inflammatory skin conditions and preventing UV-induced skin cancer.
Article
Environmental Sciences
Emad H. M. Hassanein, Basel A. Abdel-Wahab, Fares E. M. Ali, Omnia A. M. Abd El-Ghafar, Magy R. Kozman, Souty M. Z. Sharkawi
Summary: The study demonstrated that TFA has potential protective effects against CDDP-induced testicular injury by reducing oxidative stress and inflammatory response. It also enhanced the cytotoxic effect of CDDP in vitro through induction of apoptosis in both early and late stages. Additionally, TFA modulated various signaling pathways related to inflammation and cytotoxic activity.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Chemistry, Physical
Linghong Guo, Tianyou Wang, Zhixuan Li, Shuwei Wu, Yuanyuan Xu, Zhen Yang, Yiwen Li, Zhipeng Gu, Xian Jiang
Summary: Inspired by the natural photoprotective mechanism, melanin-like materials were used to enhance the efficiency and stability of sanshool, resulting in melanin-sanshool nanoparticles with uniform sizes, improved stability, effective UV absorption, and antioxidative capacities. The skin permeation, photoprotective activity, and potential mechanism of melanin-sanshool nanoparticles were investigated using cellular and animal models, providing a platform for improving the properties of naturally occurring functional molecules.
CHEMISTRY OF MATERIALS
(2023)
Review
Chemistry, Analytical
Sergio L. C. Ferreira, Victor Cerda, Lindomar A. Portugal, Lucas B. Goncalves, Joao H. Santos Neto, Joao B. Pereira Junior, Edwin Palacio
Summary: This study discusses the methods for selenium speciation analysis using CVG-AFS and their advantages and drawbacks.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2022)
Article
Geriatrics & Gerontology
Duozhuang Tang, Jianying Wu, Yiting Wang, Hui Cui, Zhendong Tao, Lang Lei, Zhuangfa Zhou, Si Tao
Summary: This study demonstrates for the first time that dietary restriction (DR) can protect mouse skin from high dose UVB radiation-induced damage. Continuous DR significantly improves UVB-induced skin damage and inflammatory responses.
REJUVENATION RESEARCH
(2022)
Review
Biology
Alena Rysava, Jitka Vostalova, Alena Rajnochova Svobodova
Summary: Excessive exposure of skin to solar radiation can lead to oxidative stress, inflammation, and various skin disorders. UV radiation triggers cellular changes, with the Nrf2 signaling pathway playing a key role in response to oxidative damage.
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
(2021)
Article
Genetics & Heredity
Yuanbin Lin, Zhanglei Cao, Tianqi Lyu, Tong Kong, Qian Zhang, Kerong Wu, Yuhui Wang, Jianping Zheng
Summary: UV irradiation induces skin damage and inflammation, with fibroblast inflammation and differential gene expression observed in UV-irradiated mouse skin. Macrophages were found to play a significant role in tissue repair, and vitamin D was shown to inhibit skin inflammation in cell culture studies.
Article
Pathology
Betul Yalcin, Arzu Hanim Yay, Fazile Canturk Tan, Saim Ozdamar, Oguz Galip Yildiz
Summary: Radiotherapy is commonly used for cancer treatment, and this study aimed to investigate the effects of melatonin on liver tissues exposed to radiation. Rats were divided into different groups and received radiation with or without melatonin treatment. Histological and biochemical analyses were performed on the liver tissues. The results showed that melatonin treatment attenuated the structural and immunoreactive changes caused by radiation, and it also decreased biochemical markers of liver damage. Administration of melatonin before radiation showed more beneficial effects. In conclusion, daily use of melatonin could mitigate radiation-induced damage in the liver.
PATHOLOGY RESEARCH AND PRACTICE
(2023)
Article
Dermatology
Rhonda M. Brand, John Mark Stottlemyer, Melissa C. Paglia, Cara Donahue Carey, Louis D. Falo
Summary: Excessive UV radiation disrupts skin homeostasis by multiple mechanisms beyond simple erythema, and combined UV exposure with excessive alcohol consumption synergistically increase local skin damage severity, impairing melanin responses, reducing antioxidants, increasing DNA damage, and dysfunctioning immune responses.
JOURNAL OF DERMATOLOGICAL SCIENCE
(2021)
Article
Cardiac & Cardiovascular Systems
Jian An, Ye Du, Xiaohong Li, Qingbo Bao, Yanqing Guo, Yang Song, Yongping Jia
Summary: The study demonstrates that early application of sacubitril-valsartan has a protective effect on rats with acute myocardial infarction. The sacubitril-valsartan group showed a reduction in left ventricular volume and collagen fiber range, as well as an increase in ejection fraction compared to the valsartan group.
Article
Cardiac & Cardiovascular Systems
Neel M. Butala, Yang Song, Changyu Shen, David J. Cohen, Robert W. Yeh
Summary: Intensive monitoring in TAVR trials resulted in more monitoring action items, but did not significantly affect trial outcomes. Tailored limited monitoring strategies can be implemented without influencing the integrity of TAVR trial outcomes.
AMERICAN HEART JOURNAL
(2022)
Article
Peripheral Vascular Disease
Manish Saxena, Roland E. Schmieder, Ajay J. Kirtane, Felix Mahfoud, Joost Daemen, Jan Basile, Philipp Lurz, Philippe Gosse, Kintur Sanghvi, Naomi D. L. Fisher, Lars C. Rump, Atul Pathak, Peter J. Blankestijn, Anthony Mathur, Yale Wang, Michael A. Weber, Andrew S. P. Sharp, Michael J. Bloch, Neil C. Barman, Lisa Claude, Yang Song, Michel Azizi, Melvin D. Lobo
Summary: This post-hoc analysis of the RADIANCE-HTN SOLO study found that predictors of response to renal denervation (RDN) included higher baseline daytime ambulatory diastolic blood pressure and use of antihypertensive medications, with orthostatic hypertension potentially predicting response. Obese females also appeared to have a better response to RDN in an interaction model.
JOURNAL OF HUMAN HYPERTENSION
(2022)
Letter
Cardiac & Cardiovascular Systems
Mabel Chung, Kamil F. Faridi, Dhruv S. Kazi, Zaid I. Almarzooq, Yang Song, Suzanne J. Baron, Robert W. Yeh
Article
Biochemistry & Molecular Biology
Jiefan Gao, Li Wang, Lei Bu, Yangyang Song, Xiao Huang, Jing Zhao
Summary: This research investigates the impact of 1,25VitD3 on the regulatory T cells/Th17 axis and the expressions and concentrations of related cytokines in women with URSA. The results suggest that 1,25VitD3 plays a role in modulating immune responses by strengthening Tregs function and inhibiting inflammatory responses of Th17 cells, which may be beneficial for successful pregnancy outcomes.
CURRENT MOLECULAR PHARMACOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Nino Mihatov, Eric A. Secemsky, Dean J. Kereiakes, P. Gabriel Steg, Donald E. Cutlip, Ajay J. Kirtane, Roxana Mehran, Bokai Zhao, Yang Song, C. Michael Gibson, Robert W. Yeh
Summary: In a low-bleeding risk population, stratifying patients based on predicted ischemic risk and the DAPT score best discerned benefit versus harm of extended DAPT duration on ischemic events, bleeding events, and NACE.
CARDIOVASCULAR REVASCULARIZATION MEDICINE
(2022)
Letter
Critical Care Medicine
Anica C. Law, Wei Tian, Yang Song, Jennifer P. Stevens, Allan J. Walkey
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2022)
Article
Psychology, Social
Yang Song, Sitong Liu, Yongfang Liu
Summary: This study explored the effects of family-of-origin triangulation on marital stability in China and the mediating roles of parenting sense of competence and coparenting. The results showed a negative association between family-of-origin triangulation and marital stability, with coparenting playing a mediating role, while parenting sense of competence did not have a significant mediating effect.
SOCIAL BEHAVIOR AND PERSONALITY
(2022)
Article
Environmental Sciences
Haidong Li, Xiaoqi Tao, Erqun Song, Yang Song
Summary: Iron oxide nanoparticles (IONPs) are an important component of airborne particulate matter and may have adverse effects on respiratory health. This study found that IONPs interact with pulmonary surfactant, leading to reduced cellular uptake and increased cytotoxicity. Mechanistic studies showed that IONPs react with intracellular hydrogen peroxide, generating hydroxyl radicals and causing oxidative stress, lipid accumulation, and inflammation.
Article
Cardiac & Cardiovascular Systems
Anna K. Krawisz, Sahana Natesan, Rishi K. Wadhera, Siyan Chen, Yang Song, Robert W. Yeh, Michael R. Jaff, Jay Giri, Howard Julien, Eric A. Secemsky
Summary: Black adults in the United States have a higher incidence of peripheral artery disease and limb amputations compared to White adults. Racial differences exist in the incidence and outcomes of peripheral endovascular intervention (PVI). Black adults who undergo PVI are younger, more likely to be female, and have a higher burden of comorbidities. They are also more likely to undergo PVI for chronic limb-threatening ischemia. The association between Black race and adverse outcomes is driven by a higher burden of comorbidities. Early identification and aggressive management of risk factors and comorbidities are important in reducing racial disparities in peripheral artery disease and adverse events after PVI.
Article
Cardiac & Cardiovascular Systems
Ashley N. Kyalwazi, Emefah C. Loccoh, LaPrincess C. Brewer, Elizabeth O. Ofili, Jiaman Xu, Yang Song, Karen E. Joynt Maddoxe, Robert W. Yeh, Rishi K. Wadhera
Summary: Over the past 20 years, cardiovascular mortality rates have declined significantly for Black and White adults in the United States, but disparities still exist, especially in terms of geographic determinants of health and residential racial segregation.
Review
Physiology
Yangyang Song, Lei Chen, Meng Wang, Quan He, Jinhong Xue, Hongli Jiang
Summary: This network meta-analysis study found that combined training and moderate-vigorous intensity exercise may be the most effective interventions for improving physical function and blood pressure control in hemodialysis patients.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Environmental Sciences
Jia Gu, Wei Zhang, Sai Xu, Yang Song, Jun Ma
Summary: This study systematically investigates the role of hydrogen sulfide (H2S) in the transformation of tetrachloro-p-benzoquinone (TCBQ) under UV irradiation. The findings show that the first triplet state of TCBQ can react with bisulfide anion (HS-) to form primary dechlorination product (HS-TriCBQ). The addition of nucleophiles (OH- or HS-) to the hydroxyl or thiol group is the most efficient pathway for dechlorination, and electron transfer from HS- can generate hydrosulfide radical for the dechlorination of TCBQ.
Article
Chemistry, Physical
Jiabao Guo, Yizhuo Zhao, Peng Wang, Yang Song, Yifei Shao, Li Zhu, Xiaoquan Yao
Summary: In this study, a novel copper loaded nitrogen-rich mesoporous carbon nitride material was designed and synthesized as a highly efficient photocatalyst for the selective cleavage of inert C-C bonds of amines under blue light irradiation. With the use of benign oxidant oxygen, good to excellent yields were achieved for various functionalized amines at room temperature, including sluggish aliphatic amines. This method offers a cost-effective and environmentally friendly alternative for the direct oxidative cleavage of amines.
JOURNAL OF MATERIALS CHEMISTRY A
(2022)
Article
Spectroscopy
Tian Peng, Xiao Xue-song, Su Gui-tian, Duan Han-feng, Jin Yao-dong, Song Yang-yang, Huang Tao, Zhang Hang
Summary: Ionic liquids have unique properties that make them attractive in the chemical industry and related fields. However, their classification as green solvents requires further study on their toxicity, degradation, and environmental impact. Therefore, the development of detection methods for ionic liquids in different solvents is of great importance.
SPECTROSCOPY AND SPECTRAL ANALYSIS
(2022)