4.7 Article

Controllable self-assembly of parallel gold nanorod clusters by DNA origami

Journal

CHINESE CHEMICAL LETTERS
Volume 30, Issue 1, Pages 175-178

Publisher

ELSEVIER SCIENCE INC
DOI: 10.1016/j.cclet.2018.04.020

Keywords

Gold nanorod; DNA origami; Cluster; Plasmonic; Self-assembly

Funding

  1. National Natural Science Foundation of China [21504053, 21661162001, 21673139, 91527304, 21722502]
  2. Shanghai Pujiang Talent Project [16PJ1402700]
  3. Innovation Fund from Joint Research Center for Precision Medicine set up by Shanghai Jiao Tong University & Affiliated Sixth People's Hospital South Campus [IFPM 2016B001]
  4. special program for collaborative innovation in Shanghai University of Medicine & Health Sciences [SPCI-17-15-001]

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Herein we demonstrate the construction of three types of parallel gold nanorod (AuNR) clusters using a DNA origami rod (DOR) as the template. Based on the precise control over the position of capture strands on DOR, number and orientation of the AuNR clusters can be well engineered, as evidenced by biological transmission electron microscope (TEM). Importantly, the AuNR clusters exhibit chiroptical responses which are strongly affected by the number of AuNR on rod-like DNA origami. (C) 2018 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.

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