Article
Engineering, Biomedical
P. Swider, F. Delanoe, F. Jalbert, S. Boetto, P. Assemat, E. Estivalezes, F. Lauwers
Summary: Scaphocephaly, a form of craniosynostosis, is characterized by higher stiffness but lower effective Young's modulus in the fused sutures compared to adjacent parietal tissue. The study also highlights structural and mechanical differences between the stenotic sutures and surrounding bone during the first year of cranial growth.
CLINICAL BIOMECHANICS
(2021)
Article
Surgery
Sultan Z. Al-Shaqsi, Nicole Wing Lam, Christopher R. Forrest, John H. Phillips
Summary: Sagittal craniosynostosis is a common congenital cranial deformity, with surgical interventions including open cranial vault reconstruction and endoscopic suturectomy. A study comparing the morphological outcomes of these techniques found that both were effective in achieving over 70% correction of head shape deformities in children with this condition.
JOURNAL OF CRANIOFACIAL SURGERY
(2021)
Article
Surgery
Thais Miguel Monte, Rafael Denadai, Cesar Augusto Raposo-Amaral, Enrico Ghizoni, Cassio Eduardo Raposo-Amaral
Summary: Limited research on long-term craniofacial changes and quality of life outcomes after pi-plasty procedures led to this study, which found significant increases in facial angles over 5 years. Patients reported high satisfaction with their appearance, positively impacting their quality of life.
JOURNAL OF CRANIOFACIAL SURGERY
(2021)
Article
Clinical Neurology
Yasin Bocu, Hakan Karabagli, Mevlut Ozgur Taskapilioglu, Gokhan Ocakoglu
Summary: This study investigated the shape differences in the corpus callosum of scaphocephaly patients before and after treatment using a landmark-based geometric morphometric method. The results showed an enlargement of the splenium part of the corpus callosum after cranial vault expansion.
CHILDS NERVOUS SYSTEM
(2022)
Review
Clinical Neurology
Federico D. I. Rocco, Mark R. Proctor
Summary: Craniosynostosis has experienced various treatment approaches, but controversy still exists regarding the ideal treatment, surgical technique, optimal age for surgery, and long-term outcomes. Molecular diagnosis has provided insights into the pathogenesis of associated malformations and neurodevelopmental issues. Future research should focus on longer-term outcome analysis, understanding the natural history of craniofacial conditions, and exploring the potential of artificial intelligence in diagnosis and surgical planning.
CHILDS NERVOUS SYSTEM
(2023)
Article
Surgery
Martin Van Carlen, William Dawes, Anusha Hennedige, Ajay Sinha, Patrishia Bordbar, Chris Parks, Partha Vaiude, Rakhee Nayar, Debbie Quirk, David Richardson, Christian Duncan
Summary: The aim of this study was to develop a simple assessment tool for scaphocephaly by using a red/amber/green (RAG) scoring system. Standard photographic views of 20 patients who had undergone scaphocephaly surgery were evaluated by 5 experienced assessors. The results showed that the RAG scoring system can be used to assess esthetic change following scaphocephaly correction and can provide both visual and numerical indicators of change.
JOURNAL OF CRANIOFACIAL SURGERY
(2023)
Article
Clinical Neurology
Pierre-Aurelien Beuriat, Alexandru Szathmari, Julie Chauvel-Picard, Arnaud Gleizal, Christian Paulus, Carmine Mottolese, Federico Di Rocco
Summary: This study revealed the formation of neosutures in the area of coronal and lambdoid sutures following total vault remodeling in patients with sagittal craniosynostosis. The reappearance of neosutures is common, indicating potential genetic and functional differences among cranial sutures.
NEUROSURGICAL FOCUS
(2021)
Article
Developmental Biology
Jeremy M. Schraw, J. P. Woodhouse, Peter H. Langlois, Mark A. Canfield, Angela E. Scheuerle, A. J. Agopian, Renata H. Benjamin, Philip J. Lupo
Summary: This study investigated the associations between maternal/infant characteristics and isolated craniosynostosis, including its subtypes. It found some associations and evaluated the trends in prevalence of these conditions. The prevalence of isolated craniosynostosis increased during the study period, with the highest increase observed in metopic synostosis, possibly explained by changes in the population distribution of associated maternal/infant characteristics.
BIRTH DEFECTS RESEARCH
(2021)
Article
Clinical Neurology
Jose Erasmo Dal'Col Lucio, Hamilton Matushita
Summary: This study evaluated the impact of surgical repair in remodeling the skull base in children with scaphocephaly by anthropometric measures. The results showed that surgical treatment led to a normalization of cranial index and proportional growth of certain skull base measures, indicating successful remodeling of the skull base.
CHILDS NERVOUS SYSTEM
(2021)
Article
Clinical Neurology
Peter Spazzapan, Miha Verdenik, Tomaz Velnar
Summary: The aim of this study was to compare the outcomes of two surgical techniques for treating isolated sagittal synostosis using 3D stereophotogrammetry. The Renier's H technique (RHT) involved biparietal expansion, while the total vault remodeling (TVR) also included frontal remodeling. The results showed that TVR led to a better aesthetic outcome, particularly in relation to the frontal bossing correction.
CHILDS NERVOUS SYSTEM
(2023)
Article
Biotechnology & Applied Microbiology
Michele Bertolini, Marco Rossoni, Giorgio Colombo
Summary: 3D digital models offer better visualization of anatomical structures, improving the realism of heart models for complex surgical planning and medical education in the cardiovascular field. Challenges in generating accurate heart models, the impact of printing technology and materials on model precision, and the evaluation of print accuracy are discussed in this study.
BIOENGINEERING-BASEL
(2021)
Article
Surgery
Lisa M. Abernethy, Dwiesha L. England, Ciera A. Price, Phillip M. Stevens, Shane R. Wurdeman
Summary: This study aimed to identify the most responsive cranial height for measuring cephalic index (CI) following cranial remolding therapy for infants with sagittal suture craniosynostosis. The results showed that measurement at CI-7 demonstrated the greatest responsiveness to treatment, while the traditional measurement at CI-3 was the least responsive.
JOURNAL OF CRANIOFACIAL SURGERY
(2022)
Article
Chemistry, Analytical
Myung Hye Cho, Mohamed A. A. Hegazy, Min Hyoung Cho, Soo Yeol Lee
Summary: Cone-beam dental CT provides high-precision 3D images of teeth and bones, but artifacts caused by incomplete projection data can introduce significant errors in 3D models. Model errors were found to increase with cone-beam angle, with the combined half-scan image reconstruction algorithm showing smaller errors.
Review
Dentistry, Oral Surgery & Medicine
Alisa O. Girard, Robin Yang
Summary: The presentation of minor suture craniosynostosis can vary, and it can still cause increased intracranial pressure. The management and treatment should address both the deformity and expansion of the skull.
ORAL AND MAXILLOFACIAL SURGERY CLINICS OF NORTH AMERICA
(2022)
Article
Polymer Science
Afsoon Farzan, Sedigheh Borandeh, Jukka Seppala
Summary: This study successfully synthesized biodegradable, conductive, solvent-free polyurethane/PEGylated graphene oxide (PU/PEG-GO) composites and 3D printed them into flexible nerve conduits with different geometries using stereolithography. The composite containing 5% PEG-GO showed the highest mechanical properties and conductivity, as well as good biocompatibility and biodegradability, making it a potential candidate for peripheral nerve regeneration.
EUROPEAN POLYMER JOURNAL
(2022)
Article
Clinical Neurology
Andrew Joshua Kobets, Aleka Scoco, Jonathan Nakhla, Allan Leonard Brook, Merritt Drew Kinon, Nrupen Baxi, David Altschul
OPERATIVE NEUROSURGERY
(2018)
Article
Clinical Neurology
Andrew J. Kobets, James T. Goodrich
CHILDS NERVOUS SYSTEM
(2018)
Article
Clinical Neurology
Andrew J. Kobets, Daniel Komlos, John K. Houten
CHILDS NERVOUS SYSTEM
(2018)
Review
Clinical Neurology
Andrew Kobets, Adam Ammar, Kamilah Dowling, Alan Cohen, James Goodrich
CHILDS NERVOUS SYSTEM
(2020)
Article
Clinical Neurology
Andrew Kobets, David Oriko, Mari Groves, Shenandoah Robinson, Alan Cohen
Summary: Labrune syndrome (LS) is a rare white matter disease characterized by brain cysts and calcifications. Surgical intervention is recommended for patients with progressive symptoms and growing lesions on imaging studies. Less-invasive stereotactic approaches with reservoir placement are favored for surgical treatment.
CHILDS NERVOUS SYSTEM
(2021)
Review
Clinical Neurology
Andrew J. Kobets, Jeffrey Oliver, Alan Cohen, George Jallo, Mari L. Groves
Summary: This study reported on 9 patients with concurrent split cord malformation and tethered cord, with an average follow-up of 8.9 years. The most common symptoms were radiating leg pain and lower extremity paresthesias, while bladder/bowel dysfunction, worsening scoliosis, and acute motor deterioration were less common. Two patients were successfully managed conservatively, while those who underwent surgery experienced symptomatic relief initially but some had late symptomatic recurrence.
CHILDS NERVOUS SYSTEM
(2021)
Article
Dentistry, Oral Surgery & Medicine
Edward Ranulph Bader, Andrew Joshua Kobets, Adam Ammar, James Tait Goodrich
Summary: This study aimed to identify factors predicting complications following cranioplasty. The study found that patients below 60 years old, avoiding the use of titanium mesh cranioplasties, and reducing the craniectomy-cranioplasty interval can decrease the occurrence of complications.
JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY
(2022)
Review
Clinical Neurology
Andrew J. Kobets, Samuel Ahmad, Andre Boyke, David Oriko, Ryan Holland, Rachel Eisenberg, Seyed Ahmad Naseri Alavi, Rick Abbott
Summary: This article reports a case of a child with a rare early-onset STAT5b gain-of-function mutation who developed cranial Mycobacterium avium osteomyelitis after treatment with targeted JAK inhibition. A literature review revealed the rarity of this disease.
CHILDS NERVOUS SYSTEM
(2023)
Article
Clinical Neurology
Amir Rezakhah, Andrew J. Kobets, Faezeh Emami Sigaroudi, Ata Mahdkhah, Jalal Barshan, Ali Gharajedaghi, Seyed Ahmad Naseri Alavi
Summary: This study investigated the relationship between clinical and laboratory findings at admission and Glasgow Outcome Scale (GOS) score in children with traumatic brain injury. The results showed that hypotension, hyponatremia, prolonged prothrombin time, prolonged partial thromboplastin time, pupil size, pupil reaction to light, and Glasgow Coma Scale score were significantly correlated with GOS score.
WORLD NEUROSURGERY
(2023)
Article
Clinical Neurology
Aleka Scoco, Kainaat Javed, Reza Yassari
Summary: This is a case report of primary CNS leiomyosarcoma. The patient, a 30-year-old female with congenital HIV, presented with shoulder pain, paresthesias of the right upper extremity and gait instability. MRI showed a contrast enhancing dural-based spinal canal lesion measuring 1.5 cm. Surgery was initially deferred but when the lesion grew to 2.6 cm, the patient underwent emergency surgery and a primary CNS leiomyosarcoma was confirmed. Another brain lesion was discovered and treated with surgical resection and proton beam radiotherapy.
SPINAL CORD SERIES AND CASES
(2023)
Article
Neuroimaging
M. E. Wagshul, J. P. McAllister, D. D. Limbrick, S. Yang, W. Mowrey, J. T. Goodrich, A. Meiri, D. M. Morales, A. Kobets, R. Abbott
Summary: The study used MRE to assess brain stiffness in hydrocephalus patients compared to healthy controls, finding that patients had significantly lower brain stiffness. Among patients, lower stiffness was associated with factors such as age, gender, and ventricular volume, and predicted clinical outcomes such as quality of life and depression.
NEUROIMAGE-CLINICAL
(2021)
Review
Medicine, General & Internal
Aleka N. Scoco, Aravind Addepalli, Shaoyu Zhu, Joshua Benton, Santiago R. Unda, Neil Haranhalli, Richard Zampolin, David D. Pasquale, Allan Brook, David Altschul
CUREUS JOURNAL OF MEDICAL SCIENCE
(2020)
Article
Clinical Neurology
Rafael De la Garza Ramos, Jonathan Nakhla, Murray Echt, Yaroslav Gelfand, Aleka N. Scoco, Merrit D. Kinon, Reza Yassari
GLOBAL SPINE JOURNAL
(2018)
Meeting Abstract
Clinical Neurology
Rafael De la Garza Ramos, Neil Haranhalli, Andrew J. Kobets, Jonathan P. Nakhla, Allan Brook, Reza Yassari, Eugene S. Flamm, David J. Altschul