Article
Environmental Sciences
Yuyang Peng, Min Li, Yong Huang, Bo Cheng, Zigang Cao, Xinjun Liao, Guanghua Xiong, Fasheng Liu, Chengyu Hu, Huiqiang Lu
Summary: Exposure to bifenazate has immunotoxicity and oxidative stress effects on zebrafish larvae, affecting growth and development, decreasing immune cells, and inhibiting antioxidant activity. Astaxanthin can effectively alleviate this developmental toxicity.
Article
Environmental Sciences
Ankit Chatterjee, Sukhendu Maity, Sambuddha Banerjee, Shibsankar Dutta, Madhuchhanda Adhikari, Rajkumar Guchhait, Chayan Biswas, Sukanta De, Kousik Pramanick
Summary: This study investigated the toxicity of nanopolystyrene on zebrafish oocyte and found that it induced oxidative stress and impaired reproductive functions.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Environmental Sciences
Wei Yuan, Zhaopeng Xu, You Wei, Wuting Lu, Kun Jia, Jing Guo, Yunlong Meng, Yuyang Peng, Zhanfeng Wu, Zulin Zhu, Fei Ma, Fenghua Wei, Guiyou Tian, Zhou Liu, Qiang Luo, Jinze Ma, Hao Zhang, Wenjin Liu, Huiqiang Lu
Summary: Exposure to Sulfometuron methyl (SM) led to toxicity in zebrafish early developmental stages, affecting development, immune system, locomotor behavior, oxidative stress, and cell apoptosis.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Article
Environmental Sciences
Raquel S. F. Vieira, Carlos A. S. Venancio, Luis M. Felix
Summary: The study found concentration-dependent teratogenic effects of Azoxystrobin on zebrafish embryos, but low concentrations may induce oxidative stress response. The results suggest that Azoxystrobin may pose ecotoxicological risks to non-target species.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Article
Environmental Sciences
Yi Liu, Jing Guo, Fengjie Yang, Yunyun Deng, Yuyang Peng, Yunlong Meng, Wenjin Liu, Bo Cheng, Jianping Fu, June Zhang, Xinjun Liao, Huiqiang Lu
Summary: The study showed that chlorobromoisocyanuric acid induced immune cell reduction, thymus shrinkage, upregulation of pro-inflammatory response, and oxidative stress in zebrafish. However, the antioxidant astaxanthin could significantly alleviate these toxic effects.
ENVIRONMENTAL TOXICOLOGY
(2022)
Article
Environmental Sciences
Zhenhua Yan, Yixin Zhou, Peiyuan Zhu, Xuhui Bao, Pengpeng Su
Summary: The widespread distribution of nanoplastics and nanomaterials in aquatic environments is of great concern. This study evaluated the influences of polystyrene (PS) nanoplastics on the toxicity of silver nanoparticles (AgNPs) to zebrafish embryos. The results showed that the presence of PS nanoplastics could act as a carrier of the co-existing AgNPs in waters and enhanced the alterations in gene expression caused by AgNPs.
FRONTIERS IN MARINE SCIENCE
(2023)
Article
Environmental Sciences
Feixue Liu, Xueqing Li, Babatunde Kazeem Bello, Tianmeng Zhang, Haitao Yang, Kun Wang, Jingquan Dong
Summary: With the increasing use of pesticides, there is a growing concern about the levels of residual pesticides in the aquatic environment and their impact on non-target organisms. This study focused on the acute toxic effects of difenoconazole (DFZ), a class of long-lasting fungicides, on the spleen tissue of carp. The results showed that DFZ caused severe histopathology, apoptosis, oxidative stress, and inflammation in the spleen tissue of carp, leading to tissue damage. These findings highlight the importance of ensuring the safety of aquatic organisms in pesticide usage.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2022)
Article
Environmental Sciences
Daoud Ali, Khalid E. Ibrahim, Seik Altaf Hussain, Mohamed M. Abdel-Daim
Summary: The research found that AZ fungicide can induce oxidative stress, apoptosis, histological, and genotoxic changes in the freshwater snail L. luteola, showing the potential toxicity of AZ fungicide.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Biochemistry & Molecular Biology
Yuanzhao Wu, Tianyi Chen, Yumei Xia, Jiawen Wang, Anli Wang, Binjie Wang, Jiye Wang, Weixuan Yao
Summary: This study revealed that exposure to methidathion caused developmental toxicity, cardiotoxicity, and immunotoxicity in embryogenetic zebrafish. It also impaired the locomotor activity of zebrafish and significantly affected the expression of related genes.
PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY
(2023)
Article
Marine & Freshwater Biology
Mingxing Wang, Huiyun Wang, Guoliang Chen, Juan Liu, Tingzhang Hu
Summary: In this study, the toxicological effects of Spiromesifen on zebrafish embryos were investigated. The results showed that Spiromesifen induced cytotoxicity and developmental toxicity in zebrafish embryos. The potential mechanism seemed to be related to oxidative stress and changes in apoptosis, immune, and antioxidant-related markers. The inflammatory response and antioxidant system participated in and resisted the threat of Spiromesifen to prevent tissue damage.
AQUATIC TOXICOLOGY
(2022)
Article
Fisheries
Xue Li, Li Zhang, Zilin Zhong, Sujie Sun, Jie Wu, Fasheng Liu, Zigang Cao, Huiqiang Lu, Xinjun Liao, Bing Zhou, Jianjun Chen
Summary: This study evaluated the immunotoxic and behavioral effects of sanguinarine exposure on larval zebrafish. The results showed that exposure to sanguinarine led to shorter body length, larger yolk sacs, slower heart rates, reduced number of immune cells, and altered locomotor behavior. In addition, it caused oxidative stress and increased apoptosis, as well as aberrant expression of key genes in the TLR immune signaling pathway. Overall, sanguinarine exposure may cause immunotoxicity and aberrant behavior in larval zebrafish.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Article
Environmental Sciences
Shahid Ali Rajput, Aftab Shaukat, Imran Rashid Rajput, Asghar Ali Kamboh, Zahid Iqbal, Muhammad Saeed, Rana Waseem Akhtar, Syed Aftab Hussain Shah, Muhammad Asif Raza, Ahmad El Askary, Mohamed M. Abdel-Daim, Zuhair M. Mohammedsaleh, Rabab M. Aljarai, Muna O. Alamoudi, Mashael Alhumaidi Alotaibi
Summary: Rb1 significantly increased the average daily gain and daily feed intake of mice, alleviated DON-induced immune injury, reduced oxidative stress levels, and regulated the apoptosis pathway.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Article
Fisheries
Min Li, Xueqin Wu, Jixing Zou, Yingqian Lai, Jiawen Zhang, Xiumei Chen, Xiaotian Niu, Yidi Kong, Guiqin Wang
Summary: Thymol-supplemented diets alleviate the oxidative stress, immunotoxicity, and apoptosis induced by deltamethrin in Channa argus through the regulation of the NF-KB/Nrf2/p53 pathway.
Article
Fisheries
Min Li, Xueqin Wu, Jixing Zou, Yingqian Lai, Jiawen Zhang, Xiumei Chen, Xiaotian Niu, Yidi Kong, Guiqin Wang
Summary: This study demonstrates that dietary supplementation of thymol alleviates DEL-induced immunotoxicity, oxidative stress, and apoptosis of Channa argus through the NF-kappa B/Nrf2/p53 pathway.
Article
Biochemistry & Molecular Biology
Xue Han, Xiaowen Xu, Tingting Yu, Meifeng Li, Yulong Liu, Jingli Lai, Huiling Mao, Chengyu Hu, Shanghong Wang
Summary: Exposure to Diflubenzuron resulted in cardiac developmental damage in zebrafish embryos, increased apoptotic cells and promoted the expression of apoptosis-related genes, while inhibiting the expression of some heart-related genes.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)