Article
Biochemistry & Molecular Biology
Kaixuan Hou, Yue Yang, Lei Zhu, Ruolin Wu, Zhongkun Du, Bing Li, Lusheng Zhu, Shujuan Sun
Summary: This study evaluated the effect of TCP on Eisenia fetida using a biomarker response method and found that TCP induced oxidative stress and DNA damage. The results showed that TCP induced stronger oxidative stress to E. fetida in red clay compared to other soils. The toxicity of the chlorpyrifos exposure group also varied after different durations of exposure.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2022)
Article
Environmental Sciences
Ruolin Wu, Hunan Liu, Chengbo Lu, Kaixuan Hou, Xiaole Wang, Jun Wang, Zhongkun Du, Bing Li, Lusheng Zhu, Jinhua Wang
Summary: This study investigated the toxicity of cloransulam-methyl on earthworms and the effect of TiO(2)NPs on the toxicity of cloransulam-methyl. Results showed that cloransulam-methyl and cloransulam-methyl + TiO(2)NPs increased the accumulation of reactive oxygen species, malondialdehyde, and 8-hydroxydeoxyguanosine, and altered the expression of physiologically-related genes. The co-exposure of cloransulam-methyl and TiO(2)NPs had a higher toxicity compared to cloransulam single exposure. These findings highlight the importance of evaluating the risk of cloransulam-methyl co-exposure with TiO(2)NPs in soil.
Article
Environmental Sciences
Dengtan Li, Jingwen Zhang, Chao Cheng, Kaixuan Hou, Xiaole Wang, Lusheng Zhu, Bing Li, Zhongkun Du, Jinhua Wang, Jun Wang
Summary: This study investigated the ecotoxicity of Penoxsulam (PNX) and silver nanoparticles (AgNPs) on Eisenia fetida (E. fetida). The results showed that low concentrations of PNX had little effect on E. fetida at the biochemical level, but the addition of AgNPs increased the production of reactive oxygen species and disrupted antioxidant and detoxification enzymes, resulting in lipid peroxidation and DNA damage. Furthermore, even the lowest concentration of PNX significantly affected the expression of functional genes, inducing oxidative stress and apoptosis and inhibiting reproductive behavior in E. fetida. The addition of AgNPs further increased the damage of PNX on E. fetida's intestinal tissue. Transcriptomic analysis revealed that PNX + AgNPs had a greater impact on E. fetida than PNX alone, affecting multiple pathways related to oxidative stress, inflammation, and cellular processes.
Article
Environmental Sciences
Yaqi Xu, Bing Li, Kaixuan Hou, Zhongkun Du, Samuel C. Allen, Lusheng Zhu, Wenxiu Li, Lei Zhu, Jinhua Wang, Jun Wang
Summary: Azoxystrobin, a widely used fungicide, was found to exhibit higher toxicity in natural soil compared to artificial soil when assessing its ecological risk on earthworm populations. The traditional artificial soil testing method may underestimate the ecotoxicity of azoxystrobin in a real agricultural environment.
ENVIRONMENTAL RESEARCH
(2021)
Article
Biochemistry & Molecular Biology
Mengyao Li, Xinxin Ma, Yanru Wang, Muhammad Saleem, Yong Yang, Qingming Zhang
Summary: The herbicide Carfentrazone-ethyl (CE) has sublethal toxic effects on soil earthworms, but is safe when applied at recommended doses.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2022)
Article
Soil Science
Shuwu Zhang, Shan Ren, Lei Pei, Yuhuan Sun, Fayuan Wang
Summary: This study investigated the individual and combined effects of PE microplastics and ZnO nanoparticles on earthworms and found that co-exposure caused higher zinc bioaccumulation and more pronounced toxicity response, indicating greater ecological risks.
APPLIED SOIL ECOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Arezoo Torabi Farsani, Mehran Arabi, Mohammad Shadkhast
Summary: Both fresh and expired forms of Chlorpyrifos (CPF) have toxic effects on earthworms by inducing oxidative stress at higher concentrations, leading to increased lipid peroxidation, CAT and GST activities, and decreased total antioxidant capacity. Further research is needed to understand CPF-related impairments in soil organisms.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2021)
Article
Environmental Sciences
Zhifeng Wang, Fangjie Qi, Yanfeng Shi, Zhibin Zhang, Lei Liu, Chaona Li, Lei Meng
Summary: This study found that the co-existence of PFOA and arsenic in soil enhanced the bioaccumulation of arsenic while reducing the bioaccumulation of PFOA. Higher exposure levels resulted in significant biomarker responses and oxidative damages. The Biomarker Response Index (BRI) showed a dose-effect relationship between biological health status and exposure levels, confirming that As(III) exhibited greater toxicity to earthworms than PFOA. The Effect Addition Index (EAI) evaluated the joint effects of the two toxicants, showing that the joint toxicity of PFOA and As(III) changed from synergism to slight antagonism with increasing exposure levels.
Article
Environmental Sciences
Wang Bingjie, Jiang Lei, Pan Bo, Lin Yong
Summary: The study found that GLA had low toxicity to earthworms, but exposure to GLA could decrease earthworm weight, cocoons, and larvae at the individual level. The impact of GLA on earthworms at the individual level may be due to effects on the microscopic level, therefore further research on enzyme activity and DNA damage is needed.
JOURNAL OF SOILS AND SEDIMENTS
(2022)
Article
Biochemistry & Molecular Biology
Xiaoying Li, Yue Yang, Ruolin Wu, Kaixuan Hou, Samuel C. Allen, Lusheng Zhu, Zhongkun Du, Bing Li, Jinhua Wang, Jun Wang
Summary: This study investigated the toxicity of atrazine to Eisenia fetida in different soil environments. The results showed that atrazine had a significant oxidative stress effect on earthworms, causing lipid and DNA damage. Additionally, the study revealed that the toxicity of atrazine in artificial soil did not represent its toxicity in real soil environment. Soil parameters of organic carbon, organic matter, and sand were found to be most related to the toxicity of atrazine.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2023)
Article
Engineering, Environmental
Linlin Shi, Ping Zhang, Jun Xu, Xiaohu Wu, Xinglu Pan, Lin He, Fengshou Dong, Yongquan Zheng
Summary: Cyflumetofen has been widely used in agriculture due to its strong acaricidal effect. However, its impact on non-target organisms like earthworms remains unclear. This study aimed to investigate the bioaccumulation of cyflumetofen in soil-earthworm systems and the resulting ecotoxicity. The findings showed that the highest concentration of cyflumetofen accumulated by earthworms was observed on the 7th day. Long-term exposure to cyflumetofen suppressed protein content and increased Malondialdehyde content in earthworms, leading to severe peroxidation. Transcriptome sequencing analysis revealed significant activation of catalase and superoxide-dismutase activities, as well as upregulation of genes involved in related signaling pathways. Moreover, high concentrations of cyflumetofen stimulated the detoxification pathway of the metabolism of glutathione. The study also identified three detoxification genes with synergistic detoxification effects. Additionally, cyflumetofen promoted disease-related signaling pathways, affecting the transmembrane capacity and cell membrane composition, ultimately causing cytotoxicity. Superoxide-Dismutase played a significant role in detoxification through oxidative stress enzyme activity. Carboxylesterase and glutathione-S-transferase activation were also important in high-concentration treatment. These results enhance our understanding of the toxicity and defense mechanisms associated with long-term cyflumetofen exposure in earthworms.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Environmental Sciences
Yan Ge, Caide Huang, Wenhao Zhou, Zhiqiang Shen, Yuhui Qiao
Summary: This study investigated the impact of earthworm activities on the fate and availability of cadmium (Cd) in soil. The results showed that earthworm activities increased the availability of Cd in soil, while organic amendments decreased the total Cd concentration but increased the availability of Cd in disturbed soil. Moisture, pH, and total carbon contents were found to be the main factors affecting Cd bioavailability.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Environmental Sciences
Marta Jaskulak, Agnieszka Rorat, Ligia Kurianska-Piatek, Sebastian Hofman, Janusz Bigaj, Franck Vandenbulcke, Barbara Plytycz
Summary: The study found that interspecific hybrids of earthworms have more efficient cadmium bioaccumulation and detoxification mechanisms compared to pure species.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Article
Engineering, Environmental
Falin He, Xiangxiang Li, Chengqian Huo, Shanshan Chu, Zhihan Cui, Yuze Li, Jingqiang Wan, Rutao Liu
Summary: This study investigated the toxic effects of fluorene on Eisenia fetida and identified its underlying mechanisms. Results showed that fluorene caused lethality and oxidative stress on E. fetida, leading to DNA damage, protein carbonylation, and lipid peroxidation. Fluorene exposure also disrupted the reproductive system and growth of E. fetida and affected the expression of genes related to oxidative stress, growth, and reproduction. High-dose and long-term exposure had more severe poisoning effects on earthworms, and E. fetida coelomocyte DNA was highly affected by fluorene stress. These findings provide valuable insights into the ecological risks associated with fluorene-contaminated soil.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Environmental Sciences
Huimin Fu, Lizhen Zhu, Liangang Mao, Lan Zhang, Yanning Zhang, Yiming Chang, Xingang Liu, Hongyun Jiang
Summary: This study investigated the combined toxic effects of different-sized polyethylene microplastics (PE MPs) and imidacloprid pesticide (IMI) on earthworms and explored the underlying mechanisms. The results showed that the combined exposure of IMI and PE MPs inhibited the weight increase and caused epidermal damage to earthworms. It also decreased antioxidant enzymes activity and caused oxidative damage. Transcriptome analysis revealed the involvement of the ferroptosis pathway in this combined toxicity. Overall, this study provides valuable data for the ecological risk assessment of soil animals exposed to combined pollution of MPs and pesticides.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Food Science & Technology
Swarupa Ghosh, Ilika Ghosh, Manoswini Chakrabarti, Anita Mukherjee
FOOD AND CHEMICAL TOXICOLOGY
(2020)
Article
Engineering, Environmental
Ritesh Banerjee, Aditi Jana, Arpita De, Anita Mukherjee
BIOREMEDIATION JOURNAL
(2020)
Article
Public, Environmental & Occupational Health
Arpita De, Swarupa Ghosh, Manoswini Chakrabarti, Ilika Ghosh, Ritesh Banerjee, Anita Mukherjee
TOXICOLOGY AND INDUSTRIAL HEALTH
(2020)
Article
Biotechnology & Applied Microbiology
Ritesh Banerjee, Priya Goswami, Manoswini Chakrabarti, Debolina Chakraborty, Amitava Mukherjee, Anita Mukherjee
Summary: CdSe quantum dots were found to have significant genotoxic effects on the model plant Allium cepa, associated with oxidative stress. The retention of Cd in roots led to genotoxicity, activating both antioxidant scavengers and enzymes. Concentrations as low as 25 nM CdSe QDs were cytotoxic, while 50 nM CdSe QDs were genotoxic to the plant.
MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
(2021)
Article
Environmental Sciences
Swarnali Dey, Subhabrata Paul, Anish Nag, Ritesh Banerjee, Geetha Gopal, Amitava Mukherjee, Rita Kundu
Summary: This study elucidated the efficacy of iron-pulsing in improving rice yield, with 72 hours treatment identified as the ideal duration. Treatment can promote seedling emergence attributes and increase water uptake through aquaporin expression regulation. After transplantation, treated plants showed enhanced photosynthetic rate and chlorophyll content.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Mathematical & Computational Biology
Anish Nag, Ritesh Banerjee
Summary: In this study, 12 phytochemicals from ginger rhizome extract were identified and evaluated for drug likeliness through in silico docking with target proteins. Multivariate statistical analysis and pharmacophore analysis helped identify common functional descriptors and chemical clusters in the compounds. A unique three-level network was developed to integrate phytochemicals, target proteins, and associated diseases based on optimal docking scores. Oleic acid, Palmitic acid, and Shogaol showed the highest coverage to target proteins, with Oleic acid scoring the highest against Peroxisome proliferator-activated receptor gamma in PatchDock. This research provides important insights into developing a protocol for rapid identification of potential drug likeliness of phytochemicals.
NETWORK MODELING AND ANALYSIS IN HEALTH INFORMATICS AND BIOINFORMATICS
(2021)
Article
Biology
Anish Nag, Subhabrata Paul, Ritesh Banerjee, Rita Kundu
Summary: The world is currently facing a pandemic outbreak of COVID-19 caused by SARS-CoV-2, with the virus entering the human host through interaction with ACE2 protein. While vaccines target the S spike protein, recent mutations in the region may escape vaccine immunity. Curcumin and piperine have been identified as potential therapeutic compounds that can effectively target mutated S spike protein and limit viral entry.
COMPUTERS IN BIOLOGY AND MEDICINE
(2021)
Article
Multidisciplinary Sciences
Yerramilli Vimala, Umesh Chandra Lavania, Ritesh Banerjee, Seshu Lavania, Anita Mukherjee
Summary: Using plants to stabilize and inactivate toxic compounds in contaminated soil is a cost-effective green technology, but sustainable implementation requires addressing contamination, soil degradation, and dispersal of particulate matter. Selecting plant genotypes like vetiver grass can help minimize toxicity levels and stabilize degraded soil, while utilizing aboveground biomass as safe fodder ensures renewable and sustainable eco-plantations.
NATIONAL ACADEMY SCIENCE LETTERS-INDIA
(2022)
Article
Biology
Anish Nag, Ritesh Banerjee, Subhabrata Paul, Rita Kundu
Summary: This study found that curcumin could be a potential therapeutic agent against the Omicron variant of SARS-CoV-2. It has inhibitory potential against the Omicron S protein and can disrupt the Omicron S-hACE2 complex.
COMPUTERS IN BIOLOGY AND MEDICINE
(2022)
Article
Plant Sciences
Ritika Dadhwal, Ritesh Banerjee
Summary: Morus alba L. is traditionally used to cure ailments in many Asian, South African, and European countries. It has economic value due to its sweet and nutritious fruits and serves as a crucial component of the silk industry. Extensive studies have been conducted on its phytochemistry, ethnopharmacology, and toxicological profile, with promising results. However, there are few comprehensive reviews on this topic.
SOUTH AFRICAN JOURNAL OF BOTANY
(2023)
Article
Tropical Medicine
Anish Nag, Ritesh Banerjee, Priya Goswami, Maumita Bandyopadhyay, Anita Mukherjee
Summary: This study compared the antioxidant and anti-genotoxic properties of Alpinia galanga, Curcuma amada, and Curcuma caesia, with Curcuma amada showing potential bioactive molecules and strong antioxidant activities. The study also confirmed the anti-genotoxicity of Curcuma amada against oxidative stress induced by cyclophosphamide.
ASIAN PACIFIC JOURNAL OF TROPICAL BIOMEDICINE
(2021)
Article
Cell Biology
J. Manivannan, Ritesh Banerjee, Anita Mukherjee
