Simultaneous quadruple-channel optical transduction of a nanosensor for multiplexed qualitative and quantitative analysis of lectins

A multichannel optical nanosensor capable of identifying and quantitating multiple lectins simultaneously was developed. The quadruple channel of fluorescence and scattering signals can be in situ collected from the same solution system, which offers high accuracy, discrimination resolution and measurement convenience. This nanosensor can in principle be generalized to the analysis of all lectins and saccharide binding organisms.