Article
Chemistry, Analytical
Charlene Gadroy, Rassen Boukraa, Nicolas Battaglini, Franck Le Derf, Nadine Mofaddel, Julien Vieillard, Benoit Piro
Summary: An electrolyte-gated graphene field-effect transistor is developed to detect Gd3+ ions in water. The transistor has source and drain electrodes fabricated by photolithography, and the graphene channel obtained through inkjet printing and electro-reduction of graphene oxide ink. The Gd3+-selective ligand DOTA is functionalized with an alkyne linker to be grafted on a gold electrode, and its affinity for Gd3+ is retained. The functionalized electrode is used as the gate in the graphene transistor to modulate the source-drain current based on the Gd3+ concentration on the gate surface.
Article
Chemistry, Physical
T. Leelasree, Mudit Dixit, Himanshu Aggarwal
Summary: Developing materials that can differentiate between chemically similar substances is challenging, especially for aliphatic and aromatic amines. Metal-organic frameworks (MOFs) with permanent porosity have been designed for discriminative sensing of amines and on-site detection of ammonia. Two Co-based multifunctional MOFs were utilized, where aliphatic amines led to turn-off fluorescence and aromatic amines showed turn-on fluorescence intensities. Real-time sensing experiments with MOF-based mixed matrix membranes demonstrated an instant color change when ammonia was released.
CHEMISTRY OF MATERIALS
(2023)
Article
Materials Science, Multidisciplinary
Shiqi Zhang, Li Li, Yang Lu, Junyao Zhang, Dapeng Liu, Dandan Hao, Xuan Zhang, Li Tian, Lize Xiong, Jia Huang
Summary: Sensing materials based on ionically conductive metal-organic frameworks (IC-MOFs) with metal ions as charge carriers were developed for detecting cadaverine vapor, an important chemical marker of food spoilage. Among different types of IC-MOFs, IC-CuTHPP-MOFs showed the greatest response to cadaverine, with a detection limit of 4.9 nL. These sensors demonstrated high sensitivity, selectivity, and stability, with a fast and real-time response to rotting meat.
JOURNAL OF MATERIALS CHEMISTRY C
(2022)
Article
Chemistry, Multidisciplinary
Haeyeon Lee, Minho Jin, Hyun-Jae Na, Changik Im, Jae Hak Lee, Jiyeon Kim, Yong Jun Gong, Chan Lee, Eungkyu Lee, Youn Sang Kim
Summary: This study proposes a water-in-bisalt/polymer electrolyte-gated synaptic transistor treated with ultraviolet ozone, which exhibits multiple synaptic functions and improved long-term plasticity. Surface engineering plays a crucial role in enhancing ion transport efficiency, and the trap sites generated by UV light and active oxygen during UVO treatment contribute to capturing lithium cations for better device performance.
ADVANCED FUNCTIONAL MATERIALS
(2022)
Article
Materials Science, Multidisciplinary
T. Leelasree, Himanshu Aggarwal
Summary: This study explores the use of metal-organic frameworks (MOFs) for real-time detection of food spoilage indicators, such as putrescine and cadaverine, in protein-rich foods like fish and cheese. Two new cobalt-based MOFs have been developed for detecting putrescine and cadaverine using fluorescence. These MOFs show unprecedented quenching efficiency of over 90% in the presence of very low concentrations of these indicators. Real-time sensing experiments with fish and cheese samples have shown the potential of these MOFs in detecting biogenic amines.
JOURNAL OF MATERIALS CHEMISTRY C
(2022)
Article
Computer Science, Information Systems
Donghoon Kim, Wonyeong Choi, Seonghwan Shin, Jiwon Park, Kihyun Kim, Bo Jin, Jeong-Soo Lee
Summary: Si-based electrolyte-gated transistors have been investigated for high sensitivity and low detection limit. The lumped-capacitive model was applied to analyze the influence of receptor-target conjugates on sensing performance. The sensitivity is enhanced in the subthreshold regime with a positive effective dipole potential and a small effective capacitance of the functionalization layer in an n-type EGT.
Article
Food Science & Technology
Hossein Ahangari, Sevinc Kurbanoglu, Ali Ehsani, Bengi Uslu
Summary: The review discusses the use of enzyme-based biosensors for detecting biogenic amines in foods using different transducers, such as chemiluminescent, surface-enhanced raman scattering biosensors, electrochemical, and fluorescence biosensors. It also covers the discussion on nanozymes-based detection of biogenic amines in foods with recent applications. Furthermore, the latest advances in biogenic amines detection using enzyme-based biosensors and nanozyme-based methods are further tabulated.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2021)
Article
Chemistry, Analytical
Donghoon Kim, Bo Jin, Sol-A Kim, Wonyeong Choi, Seonghwan Shin, Jiwon Park, Won-Bo Shim, Kihyun Kim, Jeong-Soo Lee
Summary: The highly sensitive detection of peanut allergens using silicon-based electrolyte-gated transistors was demonstrated. The Si-EGTs showed excellent electrical characteristics and were able to selectively detect PAs through surface functionalization and antibody immobilization. The voltage-related sensitivity remained constant in the subthreshold regime to the linear regime, while the current-related sensitivity decreased significantly as the drain current increased. The Si-EGTs achieved a low limit of detection of 25 pg/mL, the lowest reported value for various sensor methodologies. Selective detection of PA was confirmed through a non-specific control test.
Article
Chemistry, Multidisciplinary
Ab F. Nieuwenhuis, Daniel F. Duarte Sanchez, Jin Z. Cui, Serge G. Lemay
Summary: In this study, the quasi-1D electrical current through long single conjugated polymer chains was measured using coupled ionic-electronic charge transport. It was found that fluctuations between internal conformations of the individual polymers resulted in abrupt, multilevel switches in the electrical current, consistent with theoretical simulations. Additionally, the results provided insights into the dynamics of random-coil polymers and the potential use of semiconducting polymers as electrical labels for single-molecule sensing assays.
ADVANCED MATERIALS
(2023)
Article
Food Science & Technology
Helena Vasconcelos, Jose M. M. M. de Almeida, Ana Matias, Cristina Saraiva, Pedro A. S. Jorge, Luis C. C. Coelho
Summary: Biogenic amines (BAs) are food contaminants that can be precursors of nitrosamines, which are linked to carcinogenic and mutagenic activity. Advances have been made in analytical techniques and sample treatments for the better and faster detection of BAs in various foods.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2021)
Article
Chemistry, Organic
Peng Zhang, Tianhong Wu, Hui Cao, Jie Zhang, Tony D. James, Xiaolong Sun
Summary: In this article, a gas sensor named CA-SCH3 was developed for real-time/on-site and quantitative detection of volatile amines. The sensor exhibited a turn-on fluorescence signal and a blue shift in the UV-vis absorbance signal in the presence of ammonia. A paper-based gas sensor loaded with the probe enabled the quantification of ammonia gas and detection of volatile amines from fish spoilage. A polyethylene glycol film interlinked by the CA-SCH3 reagent provided a dual response of macroscopic degradation and fluorescence readout towards ammonia vapors. The fluorescent probe offers extensive possibilities for developing additional photoluminescent detection systems.
ORGANIC CHEMISTRY FRONTIERS
(2023)
Article
Physics, Applied
Guoru Li, Ragini Singh, Jiajun Guo, Bingyuan Zhang, Santosh Kumar
Summary: We fabricated Nb2CTx-enhanced localized surface plasmon resonance (LSPR) sensors using double S-tapered fiber sensors functionalized with gold nanoparticles/graphene oxide/tyrosinase and gold nanoparticles/Nb2CTx/tyrosinase. The Nb2CTx-enhanced LSPR sensor showed superior performance due to the presence of surface functional groups and large specific surface area of Nb2CTx. Our work provides a research platform for improving the sensitivity of LSPR sensors.
APPLIED PHYSICS LETTERS
(2023)
Article
Engineering, Electrical & Electronic
Yang Ming Fu, Hu Li, Tianye Wei, Long Huang, Faricha Hidayati, Aimin Song
Summary: The temperature-dependent synaptic plasticity behaviors in indium gallium-zinc oxide thin-film transistors gated with sputtered Si0 2 electrolytes were studied. It was found that with increasing temperature, the electrolyte capacitance decreases, the mobility increases, and the threshold voltage shifts negatively. In addition, the post-synaptic current (PSC) at the resting state increases, and the PSC signal amplitude and retention time decrease under a single gate pulse. A physical model based on electric field-induced ion drifting, ionic-electronic coupling, and gradient-coordinated ion diffusion was proposed to explain these temperature-dependent synaptic behaviors.
ACS APPLIED ELECTRONIC MATERIALS
(2022)
Article
Chemistry, Analytical
Bora Ersoez, Katrin Schmitt, Jurgen Woellenstein
Summary: The study introduces an electrolyte-gated transistor as a sensor device for CO2 detection, utilizing Electrochemical Impedance Spectroscopy for analysis. Compared to direct current and FET mode, EIS shows better sensing performance, with the sensing mechanism resembling electrostatic doping and exploiting the O-2 sensing capacity of the MOX. The developed sensor device offers a small-sized solution for ambient CO2 sensing applications.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Engineering, Electrical & Electronic
Douglas Henrique Vieira, Gabriel Leonardo Nogueira, Rogerio Miranda Morais, Lucas Fugikawa-Santos, Keli Fabiana Seidel, Neri Alves
Summary: In this study, a transparent and printed ZnO-based electrolyte-gated transistor (EGT) using cellulose electrolyte was reported. It showed low-voltage operation, high on-state current, and high field-effect mobility. The device exhibited a multiparametric response as a UV sensor when exposed to different levels of UV irradiance.
SENSORS AND ACTUATORS A-PHYSICAL
(2022)
Article
Engineering, Chemical
Yui Sasaki, Xiaojun Lyu, Zhoujie Zhang, Tsuyoshi Minami
Summary: The study introduces a minimized chemosensor array composed of two polythiophene derivatives for detection of eight metal ions, exhibiting different fluorescence response patterns upon recognition. Qualitative and quantitative discrimination of metal ions was successfully achieved through the chemosensor microarray on the glass chip. A novel approach for achieving a minimized chemosensor array by altering alkyl chain lengths without the need for numerous receptors and reporters is demonstrated.
FRONTIERS OF CHEMICAL SCIENCE AND ENGINEERING
(2022)
Article
Nanoscience & Nanotechnology
Riho Mitobe, Yui Sasaki, Wei Tang, Qi Zhou, Xiaojun Lyu, Kohei Ohshiro, Masao Kamiko, Tsuyoshi Minami
Summary: An organic field-effect transistor-based chemical sensor has been developed for detecting multiple oxyanions using pattern recognition techniques. The sensor has shown success in qualitative detection of 13 oxyanions and quantification of hydrogen monophosphate in human blood serum with low errors. This demonstrates the potential for the sensor to be used as a practical sensing platform for medical assays through a combination of OFET functionalization and pattern recognition methods.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Chemistry, Analytical
Kohei Ohshiro, Yui Sasaki, Qi Zhou, Xiaojun Lyu, Yusuke Yamanashi, Katsumasa Nakahara, Hirokazu Nagaoka, Tsuyoshi Minami
Summary: In this study, we developed an extended-gate-type organic field-effect transistor (OFET) sensor for oxytocin detection. The fabricated OFET-based immunosensor successfully detected oxytocin in human saliva at the ppt level, with high recovery rates of 96-102%. This sensor has great potential for the realization of portable sensors for healthcare monitoring.
Article
Chemistry, Multidisciplinary
Xiaojun Lyu, Yui Sasaki, Kohei Ohshiro, Wei Tang, Yousi Yuan, Tsuyoshi Minami
Summary: In this study, a printed 384-well microtiter paper-based fluorescent chemosensor array device was proposed for simultaneous categorization and discrimination of saccharides and sulfur-containing amino acids in food. The device, embedded with self-assembled fluorescence chemosensors, demonstrated a fingerprint-like response pattern for targets, and the image was captured by a portable digital camera. The results showed that the device successfully categorized and classified the analytes, and the quantitative detectability was confirmed by a spike and recovery test.
CHEMISTRY-AN ASIAN JOURNAL
(2022)
Article
Chemistry, Physical
Yui Sasaki, Xiaojun Lyu, Wei Tang, Hao Wu, Tsuyoshi Minami
Summary: In this review, we summarize the actual approaches for the fabrication of solid-state chemosensor arrays combined with powerful data processing techniques and portable digital recorders for real-world applications.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY C-PHOTOCHEMISTRY REVIEWS
(2022)
Review
Materials Science, Multidisciplinary
Yui Sasaki, Tsuyoshi Minami
Summary: This article reviews the methodologies and actual approaches to maximizing the potential of organic field-effect transistors (OFETs) as chemical sensor platforms through fusion technologies between organic electronics and molecular-recognition chemistry. Functionalized extended-gate-type OFETs have achieved real-sample analysis, indicating the acceleration of the establishment of practical chemical sensor devices through the interdisciplinary field of organic electronics and molecular-recognition chemistry.
PHYSICA STATUS SOLIDI A-APPLICATIONS AND MATERIALS SCIENCE
(2023)
Article
Chemistry, Analytical
Yuma Tanaka, Tsukuru Minamiki, Ryoji Kurita
Summary: The development of high-throughput screening methods for microorganisms is essential for efficient screening. In this study, a picoliter-sized incubator array was developed to quantitatively and labeling-free evaluate the growth process of Escherichia coli (E. coli) by autofluorescence. This array not only allows high-throughput screening of microorganisms but also provides an analytical tool for assessing individual differences in E. coli.
ANALYTICAL METHODS
(2023)
Article
Chemistry, Multidisciplinary
Kohei Ohshiro, Yui Sasaki, Qi Zhou, Pierre Didier, Takasuke Nezaki, Tomoharu Yasuike, Masao Kamiko, Tsuyoshi Minami
Summary: A microfluidic organic transistor functionalized with phenylboronic acid has been successfully developed for the reversible and real-time monitoring of H2O2 at ppb/ppt levels in ultrapure water. This technology can be used not only as portable chemical sensors but also as monitoring tools to elucidate the unknown reaction mechanisms of phenylboronic acid with H2O2.
CHEMICAL COMMUNICATIONS
(2022)
Article
Chemistry, Multidisciplinary
Linlin Du, Yijia Lao, Yui Sasaki, Xiaojun Lyu, Peng Gao, Si Wu, Tsuyoshi Minami, Yuanli Liu
Summary: This study demonstrates the quantitative detection of biogenic amines using a gold nanoparticle-based colorimetric chemosensor array for food analysis. The gold nanoparticles are modified with carboxylate derivatives to capture target amines, achieving simultaneous discrimination of 10 amine derivatives based on a multi-colorimetric response pattern. Additionally, the chemosensor array combined with support vector machine analysis successfully determines histamine concentrations in raw fish samples and monitors the time-dependent change in histamine concentration, making it a user-friendly analytical method for food freshness monitoring.
Review
Chemistry, Multidisciplinary
Dan He, Yawen Li, Fuwen Zhao, Yuze Lin
Summary: High trap density in organic solar cells leads to localized charge carriers and reduced carrier lifetime, limiting device efficiency. This feature article summarizes the recent advances of trap suppression by material design and device engineering.
CHEMICAL COMMUNICATIONS
(2024)
Review
Chemistry, Multidisciplinary
Olivier Monfort, Arshitha Madhusudhan, Martin Motola
Summary: This article presents the advantages of coupling photocatalysis and Fenton-based processes for environmental remediation and discusses their synergy. It critically examines the simultaneous triggering of these two processes and provides insights into research approaches. The study aims to enhance understanding of this complex process and highlight the potential integration of new catalysts in current wastewater treatment technology.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Manideepa Dhar, Chittaranjan Mishra, Avijit Das, Uttam Manna
Summary: An approach of 'polymerization of monomers in its aggregated form' has been introduced to tailor the water wettability of fibrous and porous substrates, achieving hydrophobicity to superhydrophobicity transition, as well as patterned wettability. This facile chemical method provides a durable coating with adjustable and patterned wettability for various potential applications.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Saswat Ranjan Bhoi, Chhanda Debnath, Shikha Gandhi
Summary: In this article, a novel catalytic reaction using Pd(0) and Bronsted acid is reported for the synthesis of biologically important imidazolidinone-fused N-heterocycles through redox-neutral intramolecular N-allylation of indoles and pyrroles with alkynes. This atom-economical method is applicable to a wide range of substrates and eliminates the need for leaving groups or oxidizing agents commonly used in traditional allylation reactions.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Longkun Chen, Mingshuai Zhang, Meichen Liu, Zhuoyuan Liu, Yuetong Qiu, Zhilai Zhang, Fuchao Yu, Jiuzhong Huang
Summary: In this study, an efficient Rh(III)-catalyzed selective mono- and dual-C-H bond functionalization/cyclization with iodonium ylide as the sole coupling partner was demonstrated. Fused benzodiazepine skeletons were obtained in excellent yields, providing an improved approach to dual C-H unsymmetrical functionalization.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Alice Kennett, Sven Epple, Gabriella van der Valk, Irene Georgiou, Evelyne Gout, Romain R. Vives, Angela J. Russell
Summary: This study presents the design and synthesis of sulfated disaccharide inhibitors based on IdoA(2S)-GlcNS(6S), which showed potent inhibition of Sulf-2. The results suggest that IdoA(2S)-GlcNS(6S) is the shortest fragment size required for effective inhibition of Sulfs, and a trisulfated disaccharide is identified as the minimal fragment size of heparan sulfate for effective endosulfatase inhibition.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Mauro Garbini, Andrea Brunetti, Riccardo Pedrazzani, Magda Monari, Massimo Marcaccio, Giulio Bertuzzi, Marco Bandini
Summary: The self-adaptability of galvanostatic electrolysis was found to be helpful in a multistage chemo- and diastereoselective electrochemically promoted cyclodimerization of chalcones. Through a series of reductive events, densely functionalized cyclopentanes with five contiguous stereocenters were obtained (25 examples, yields up to 95%, dr values up to >20:1). Further experimental and electrochemical investigations indicated the crucial role of dynamic kinetic resolution of the aldol intermediate in the reaction mechanism.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Dhananjay S. Nipate, Neha Meena, Prakash N. Swami, Krishnan Rangan, Anil Kumar
Summary: In this study, the synthesis of functionalized benzo[a]phenazines and indazolo[2,3-a]quinolines was achieved through Rh(III)-catalyzed oxidative annulation of 2-arylquinoxalines and 2-aryl-2H-indazoles with allyl alcohols. The method showed a wide substrate scope, excellent functional group tolerance, good to high yields of annulated products, and the capability for scaled-up synthesis. A tentative mechanism of the annulation reaction was proposed based on a preliminary mechanistic investigation.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Ruonan Zhang, Abudukadi Tudi, Xia Yang, Xuping Wang, Zhihua Yang, Shujuan Han, Shilie Pan
Summary: A new lead tellurium borate material with a unique fundamental building block [B4O10] was synthesized and found to exhibit high birefringence. The structure-property relationship was discussed using first-principles calculations.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Amresh Kumar Singh, Baishali Thakurta, Anupam Giri, Monalisa Pal
Summary: This study introduces three key concepts for the quick synthesis of large-scale high-quality 2D materials films and their utilization in device fabrication.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Reina Hagiwara, Shun Nishimura, Kosuke Okeyoshi
Summary: A copolymer-conjugated nanocatalytic system has been developed to improve electron transfer and enhance photoinduced H2 generation.
CHEMICAL COMMUNICATIONS
(2024)
