Article
Chemistry, Multidisciplinary
Naoya Takahashi, Hinata Iwasawa, Tatsuhito Kinashi, Kazuishi Makino, Naoyuki Shimada
Summary: In this study, a catalytic method for the synthesis of primary amides was developed through the dehydrative condensation of carboxylic acids with aqueous ammonia using diboronic acid anhydride (DBAA) as the catalyst.
CHEMICAL COMMUNICATIONS
(2023)
Article
Chemistry, Organic
Pratibha Chand-Thakuri, Indunil Alahakoon, Daniel Liu, Mohit Kapoor, John F. Kennedy, Kenneth W. Jenkins, Allison M. Rabon, Michael C. Young
Summary: Free or unfunctionalized benzylamines are commonly used in C-H activation in the presence of palladium salts. However, subsequent functionalization of the dimeric cyclometalates can be challenging. This study demonstrates a protocol for ortho-C-H chlorination and bromination of unprotected benzylamines, as well as a unique acetoxylation/-cyclization utilizing fluorine-based oxidants and the nucleophilicity of the free primary amine directing group.
SYNTHESIS-STUTTGART
(2022)
Article
Chemistry, Organic
Chiliveru Priyanka, Muppidi Subbarao, Nagender Punna
Summary: A highly regio- and stereoselective palladium-catalyzed ortho-vinylation of beta-naphthols has been reported using accessible CF3-allyl carbonates, leading to the formation of (Z)-CF3-vinylnaphthols in good yields. Furthermore, a one-pot synthesis of CF3-naphtho[2,1-b]furans was achieved through an uninterrupted ortho-vinylation/oxidative radical cyclization reaction sequence.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Yuan Lu, Jinmei Wang, Pengpeng Cheng, Chuyue Zhang, Jinghua Li, Zhimin Ou
Summary: In this study, self-assembled dual-enzyme clusters (DENCs) were successfully prepared and their assembly was verified. DENCs showed improved storage stability and pH stability compared to free enzymes. High-yield (99.9%) and high-enantiomeric excess (99.9%) synthesis of R-BPA was achieved using DENCs, and the DENCs retained high activity after five cycles.
PROCESS BIOCHEMISTRY
(2023)
Article
Chemistry, Organic
Jun Yan, Christine Tran, Pascal Retailleau, Mouad Alami, Abdallah Hamze
Summary: Functionalized 4-aryl-4H-benzo[d][1,3]oxazines were synthesized using ortho-amide-N-tosylhydrazones under transition-metal-free conditions. This method utilizes readily available N-tosylhydrazones as the diazo compound precursors and involves an intramolecular ring closure reaction mediated by a protic polar additive (iPrOH), resulting in a wide range of functionalized oxazines in good to excellent yields. Additionally, the feasibility of this strategy was demonstrated by the gram-scale elaboration of a bromo-substituted 4H-benzo[d][1,3]oxazine and its post-functionalization through palladium-catalyzed cross-couplings.
JOURNAL OF ORGANIC CHEMISTRY
(2023)
Article
Chemistry, Inorganic & Nuclear
Nadia Ismaeel, Zhixing Zhuo, Sajid Imran, Dan Yuan, Yingming Yao
Summary: Rare earth/lithium complexes stabilized by ethylenediamine-bridged bis(phenolate) ligands have been synthesized and characterized. Among them, the yttrium/lithium complex showed high catalytic activity for the amidation of primary aliphatic amines.
DALTON TRANSACTIONS
(2022)
Article
Biochemistry & Molecular Biology
Yuan Lu, Jinmei Wang, Haobo Xu, Chuyue Zhang, Pengpeng Cheng, Lihua Du, Lan Tang, Jinghua Li, Zhimin Ou
Summary: In this study, a bienzyme cascade system was constructed using ATA117 and ADH co-expression system, and (R)-1-[3,5-bis(trifluoromethyl)phenyl]ethanamine was efficiently synthesized. The introduction of ADH improved the product yield, and different expression systems were used to construct the bienzyme cascade system, enhancing substrate handling capacity.
Article
Chemistry, Organic
Angelica Salinas-Torres, Hugo Rojas, Jose J. Martinez, Diana Becerra, Juan-Carlos Castillo
Summary: In this study, a practical method for the preparation of N-(3,5-bis(trifluoromethyl)benzyl)stearamide was developed using a solventless, metal- and catalyst-free direct amidation reaction. The product was fully characterized using various analytical techniques.
Article
Chemistry, Physical
Muhammet Uyanik, Niiha Sasakura, Masahiro Mizuno, Kazuaki Ishihara
Article
Chemistry, Organic
Muhammet Uyanik, Takeshi Yasui, Kazuaki Ishihara
JOURNAL OF ORGANIC CHEMISTRY
(2017)
Article
Chemistry, Multidisciplinary
Manabu Hatano, Keisuke Nishikawa, Kazuaki Ishihara
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2017)
Article
Chemistry, Physical
Manabu Hatano, Takuya Mochizuki, Keisuke Nishikawa, Kazuaki Ishihara
Article
Chemistry, Multidisciplinary
Tatsuhiro Sakamoto, Takuya Mochizuki, Yuta Goto, Manabu Hatano, Kazuaki Ishihara
CHEMISTRY-AN ASIAN JOURNAL
(2018)
Article
Chemistry, Multidisciplinary
Manabu Hatano, Yuji Tabata, Yurika Yoshida, Kohei Toh, Kenji Yamashita, Yoshihiro Ogura, Kazuaki Ishihara
Article
Chemistry, Multidisciplinary
Yanhui Lu, Hidefumi Nakatsuji, Yukimasa Okumura, Lu Yao, Kazuaki Ishihara
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2018)
Article
Chemistry, Organic
Takahiro Suzuki, Soichiro Watanabe, Muhammet Uyanik, Kazuaki Ishihara, Susumu Kobayashi, Keiji Tanino
Article
Chemistry, Multidisciplinary
Manabu Hatano, Haruka Okamoto, Taro Kawakami, Kohei Toh, Hidefumi Nakatsuji, Akira Sakakura, Kazuaki Ishihara
Article
Chemistry, Physical
Takahiro Horibe, Yasutaka Tsuji, Kazuaki Ishihara
Article
Chemistry, Organic
Haruka Okamoto, Kohei Toh, Takuya Mochizuki, Hidefumi Nakatsuji, Akira Sakakura, Manabu Hatano, Kazuaki Ishihara
SYNTHESIS-STUTTGART
(2018)
Article
Chemistry, Organic
Muhammet Uyanik, Naoto Sahara, Kazuaki Ishihara
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
(2019)
Article
Chemistry, Physical
Shun Satake, Takumaru Kurihara, Keisuke Nishikawa, Takuya Mochizuki, Manabu Hatano, Kazuaki Ishihara, Tatsuhiko Yoshino, Shigeki Matsunaga
Article
Chemistry, Multidisciplinary
Muhammet Uyanik, Tatsuya Mutsuga, Kazuaki Ishihara
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2017)
Review
Chemistry, Multidisciplinary
Dan He, Yawen Li, Fuwen Zhao, Yuze Lin
Summary: High trap density in organic solar cells leads to localized charge carriers and reduced carrier lifetime, limiting device efficiency. This feature article summarizes the recent advances of trap suppression by material design and device engineering.
CHEMICAL COMMUNICATIONS
(2024)
Review
Chemistry, Multidisciplinary
Olivier Monfort, Arshitha Madhusudhan, Martin Motola
Summary: This article presents the advantages of coupling photocatalysis and Fenton-based processes for environmental remediation and discusses their synergy. It critically examines the simultaneous triggering of these two processes and provides insights into research approaches. The study aims to enhance understanding of this complex process and highlight the potential integration of new catalysts in current wastewater treatment technology.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Manideepa Dhar, Chittaranjan Mishra, Avijit Das, Uttam Manna
Summary: An approach of 'polymerization of monomers in its aggregated form' has been introduced to tailor the water wettability of fibrous and porous substrates, achieving hydrophobicity to superhydrophobicity transition, as well as patterned wettability. This facile chemical method provides a durable coating with adjustable and patterned wettability for various potential applications.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Saswat Ranjan Bhoi, Chhanda Debnath, Shikha Gandhi
Summary: In this article, a novel catalytic reaction using Pd(0) and Bronsted acid is reported for the synthesis of biologically important imidazolidinone-fused N-heterocycles through redox-neutral intramolecular N-allylation of indoles and pyrroles with alkynes. This atom-economical method is applicable to a wide range of substrates and eliminates the need for leaving groups or oxidizing agents commonly used in traditional allylation reactions.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Longkun Chen, Mingshuai Zhang, Meichen Liu, Zhuoyuan Liu, Yuetong Qiu, Zhilai Zhang, Fuchao Yu, Jiuzhong Huang
Summary: In this study, an efficient Rh(III)-catalyzed selective mono- and dual-C-H bond functionalization/cyclization with iodonium ylide as the sole coupling partner was demonstrated. Fused benzodiazepine skeletons were obtained in excellent yields, providing an improved approach to dual C-H unsymmetrical functionalization.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Alice Kennett, Sven Epple, Gabriella van der Valk, Irene Georgiou, Evelyne Gout, Romain R. Vives, Angela J. Russell
Summary: This study presents the design and synthesis of sulfated disaccharide inhibitors based on IdoA(2S)-GlcNS(6S), which showed potent inhibition of Sulf-2. The results suggest that IdoA(2S)-GlcNS(6S) is the shortest fragment size required for effective inhibition of Sulfs, and a trisulfated disaccharide is identified as the minimal fragment size of heparan sulfate for effective endosulfatase inhibition.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Mauro Garbini, Andrea Brunetti, Riccardo Pedrazzani, Magda Monari, Massimo Marcaccio, Giulio Bertuzzi, Marco Bandini
Summary: The self-adaptability of galvanostatic electrolysis was found to be helpful in a multistage chemo- and diastereoselective electrochemically promoted cyclodimerization of chalcones. Through a series of reductive events, densely functionalized cyclopentanes with five contiguous stereocenters were obtained (25 examples, yields up to 95%, dr values up to >20:1). Further experimental and electrochemical investigations indicated the crucial role of dynamic kinetic resolution of the aldol intermediate in the reaction mechanism.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Dhananjay S. Nipate, Neha Meena, Prakash N. Swami, Krishnan Rangan, Anil Kumar
Summary: In this study, the synthesis of functionalized benzo[a]phenazines and indazolo[2,3-a]quinolines was achieved through Rh(III)-catalyzed oxidative annulation of 2-arylquinoxalines and 2-aryl-2H-indazoles with allyl alcohols. The method showed a wide substrate scope, excellent functional group tolerance, good to high yields of annulated products, and the capability for scaled-up synthesis. A tentative mechanism of the annulation reaction was proposed based on a preliminary mechanistic investigation.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Ruonan Zhang, Abudukadi Tudi, Xia Yang, Xuping Wang, Zhihua Yang, Shujuan Han, Shilie Pan
Summary: A new lead tellurium borate material with a unique fundamental building block [B4O10] was synthesized and found to exhibit high birefringence. The structure-property relationship was discussed using first-principles calculations.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Amresh Kumar Singh, Baishali Thakurta, Anupam Giri, Monalisa Pal
Summary: This study introduces three key concepts for the quick synthesis of large-scale high-quality 2D materials films and their utilization in device fabrication.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Reina Hagiwara, Shun Nishimura, Kosuke Okeyoshi
Summary: A copolymer-conjugated nanocatalytic system has been developed to improve electron transfer and enhance photoinduced H2 generation.
CHEMICAL COMMUNICATIONS
(2024)