Journal
CHEMICAL COMMUNICATIONS
Volume 54, Issue 52, Pages 7211-7214Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c8cc03349h
Keywords
-
Categories
Funding
- EPSRC [EP/K031783/1]
- BBSRC
- EU
- Marie-Sklodowska-Curie Individual Fellowship [MSCA-IF-EF-4887, 705079]
- Research Councils UK
- EPSRC [EP/L027100/1, EP/K031783/1] Funding Source: UKRI
- Marie Curie Actions (MSCA) [705079] Funding Source: Marie Curie Actions (MSCA)
Ask authors/readers for more resources
The first total synthesis of phyllostictine A (PA) is reported, which confirms the structure of this fungal metabolite and its (6S, 7R, 8S)stereochemistry. Both synthetic PA and an analogue containing the 5-methylene-1,5-dihydro-2H-pyrrol-2-one nucleus exhibit lM inhibitory activity in root growth assays against Arabidopsis thaliana, indicating that this heterocyclic subunit is key to the herbicidal activity of the natural product.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
