Design, synthesis, and molecular docking studies of N -(9,10-anthraquinone-2-carbonyl)amino acid derivatives as xanthine oxidase inhibitors

Design, synthesis and biological evaluation of N -(4-alkoxy-3-cyanophenyl)isonicotinamide/nicotinamide derivatives as novel xanthine oxidase inhibitors

(2017) Ting-jian Zhang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Xanthine oxidase inhibitors beyond allopurinol and febuxostat; an overview and selection of potential leads based on in silico calculated physico-chemical properties, predicted pharmacokinetics and toxicity

(2017) Andrija Šmelcerović et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, cytotoxic activity, and tubulin polymerization inhibitory activity of new pyrrol-2(3H)-ones and pyridazin-3(2H)-ones

(2016) Samar Hafez Abbas et al.   BIOORGANIC CHEMISTRY

The treatment of hyperuricemia

(2016) Micaela Gliozzi et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Design and synthesis of novel 2-(indol-5-yl)thiazole derivatives as xanthine oxidase inhibitors

(2015) Jeong Uk Song et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Development of 2-(Substituted Benzylamino)-4-Methyl-1, 3-Thiazole-5-Carboxylic Acid Derivatives as Xanthine Oxidase Inhibitors and Free Radical Scavengers

(2015) Md Rahmat Ali et al.   Chemical Biology & Drug Design

Synthesis and evaluation of 1-hydroxy/methoxy-4-methyl-2-phenyl-1H-imidazole-5-carboxylic acid derivatives as non-purine xanthine oxidase inhibitors

(2015) Shaolei Chen et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

A fruitful decade from 2005 to 2014 for anthraquinone patents

(2015) Hidayat Hussain et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

HTS followed by NMR based counterscreening. Discovery and optimization of pyrimidones as reversible and competitive inhibitors of xanthine oxidase

(2014) Johan Evenäs et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and bioevaluation of 2-phenyl-4-methyl-1,3-selenazole-5-carboxylic acids as potent xanthine oxidase inhibitors

(2014) Qi Guan et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, synthesis and molecular modeling of aloe-emodin derivatives as potent xanthine oxidase inhibitors

(2014) Da-Hua Shi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

The methanol extract of Euonymus laxiflorus, Rubia lanceolata and Gardenia jasminoides inhibits xanthine oxidase and reduce serum uric acid level in rats

(2014) Li-Min Liu et al.   FOOD AND CHEMICAL TOXICOLOGY

8-(2-Furyl)adenine derivatives as A2A adenosine receptor ligands

(2013) Diego Dal Ben et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Simultaneous Preconcentration and Analysis of Anthraquinones Based on Ultrasound Emulsification Ionic Liquid Microextraction

(2013) Y. Yan et al.   JOURNAL OF CHROMATOGRAPHIC SCIENCE

Identification of novel isocytosine derivatives as xanthine oxidase inhibitors from a set of virtual screening hits

(2012) Chandrika B-Rao et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Isocytosine-based inhibitors of xanthine oxidase: Design, synthesis, SAR, PK and in vivo efficacy in rat model of hyperuricemia

(2012) Smriti Khanna et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Lead optimization of isocytosine-derived xanthine oxidase inhibitors

(2012) Komal Bajaj et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and Antitubercular Activity of Novel Amino Acid Derivatives

(2011) Cristiane F. Da Costa et al.   Chemical Biology & Drug Design

Synthesis of some 5-phenylisoxazole-3-carboxylic acid derivatives as potent xanthine oxidase inhibitors

(2010) Shaojie Wang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

FYX-051: A Novel and Potent Hybrid-Type Inhibitor of Xanthine Oxidoreductase

(2010) K. Matsumoto et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Design, synthesis, and pharmacological and pharmacokinetic evaluation of 3-phenyl-5-pyridyl-1,2,4-triazole derivatives as xanthine oxidoreductase inhibitors

(2008) Takahiro Sato et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS