Journal
FLUID PHASE EQUILIBRIA
Volume 403, Issue -, Pages 145-152Publisher
ELSEVIER
DOI: 10.1016/j.fluid.2015.06.026
Keywords
Flunixin meglumine; Solubility; Dielectric constant; Thermodynamic properties
Funding
- National Natural Science Foundation of China (NNSFC) [21376164]
- National High Technology Research and Development Program (863 program) [2012AA021202]
Ask authors/readers for more resources
The solubility of flunixin meglumine (FM) in six pure solvents and binary solvents of ethanol + isopropanol was measured over the temperature ranged from 28315 K to 328.15 K by using a static gravimetric method. It is positively correlated with temperature and negatively correlated with the molar fraction of isopropanol. The modified Apelblat equation was used to correlate the experimental solubility in pure solvents. Dissolution properties based on the modified Apelblat equation were calculated and discussed. The solubility in binary solvents at various temperatures was well correlated by the nearly ideal binary solvent (NIBS)/Redlich-Kister model. In addition, in order to correlate the solubility to both the composition and temperature in mixed solvents, a new model related to dielectric constant was proposed. (C) 2015 Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available