Article
Clinical Neurology
Nathan J. Pertsch, Spencer C. Darveau, Oliver Y. Tang, Steven A. Toms, Robert J. Weil
Summary: This study aimed to investigate risk factors associated with the timing of UTI after elective spine surgery and its short-term outcomes. The results showed that patients with post-discharge UTI were more likely to develop sepsis compared to inpatient UTI patients, while inpatient UTI patients had higher odds of 30-day mortality.
Article
Clinical Neurology
Katie S. Traylor, Raymond F. Sekula, Komal Eubanks, Nallammai Muthiah, Yue-Fang Chang, Marion A. Hughes
Summary: The study found that neurovascular compression resulting in deformity of the susceptible portion of the facial nerve is highly associated with the symptomatic side in hemifacial spasm.
Review
Biochemistry & Molecular Biology
Yair Sharav, Yaron Haviv, Rafael Benoliel
Summary: The purpose of this study is to explore the potential differences between orofacial migraine (OFM) and neurovascular orofacial pain (NVOP). Facial presentations of primary headache resemble primary headache disorders, but they occur in specific locations associated with the trigeminal nerve. The International Classification of Orofacial Pain, 1st edition (ICOP) classifies these conditions as orofacial pains resembling primary headaches, including OFM and NVOP. The subtle differences and similar response to therapy suggest a possible overlap between NVOP and OFM, and further investigations are needed to separate them into distinct entities.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Neurosciences
Oscar Bolivar-Baquero, Julieta Troncoso
Summary: Facial nerve injury has been widely used in rats to study the changes in motoneurons and other central nervous system structures related to sensorimotor processing. Recent studies have found that this injury is associated with a decrease in long-term potentiation, increased corticosterone levels, impairment in spatial memory consolidation, and hippocampal microglial activation. In this study, the neuronal morphology of hippocampal pyramidal neurons in rats with reversible or irreversible facial nerve injury was analyzed. The results showed significant decreases in dendritic tree complexity, dendritic length, branch points, and spine density of hippocampal neurons in both types of injuries, but the timing and sensitivity varied depending on the hippocampal area, dendritic area, and lesion type.
JOURNAL OF COMPARATIVE NEUROLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Atanas Pachev, Lucas Rauyaud, Luisa Paulatto, Marco Dioguardi Burgio, Vincent Roche, Carmela Garcia Alba, Annie Sibert, Matthieu Lagadec, Juliette Kavafyan-Lasserre, Catherine Paugam-Burtz, Valerie Vilgrain, Maxime Ronot
Summary: Severe abdominal pain was frequent during and after TACE for hepatocellular carcinoma. Young patients without alcoholic liver disease or cirrhosis may benefit from reinforced analgesia.
EUROPEAN RADIOLOGY
(2021)
Article
Clinical Neurology
Anton Konovalov, Mariana Tlisova, Vadim Gadzhiagaev, Fyodor Grebenev, Elizaveta Safronova
Summary: This study analyzes the experience and proposes a method of incision and stitching for post-operative scalp wounds without shaving hair. The results show that this non-shaving method was successful in 44 cases of elective neurosurgical interventions and did not increase the risk of infection.
WORLD NEUROSURGERY
(2023)
Article
Clinical Neurology
Bhavya Pahwa, Shukla Das, Gurbachan Singh, M. M. Anu
Summary: This study aimed to identify the risk factors for surgical site infections (SSI) in neurosurgical patients and assess the factors associated with infection by a specific microorganism. A retrospective case-control study was conducted, and the results showed that underlying infection, ASA score>2, duration of surgery>4 h, diabetes, and preoperative stay at the hospital were significant risk factors for SSI in neurosurgical patients. By creating a regression model, the presence of a particular organism isolated from the site of infection in neurosurgical patients can be predicted.
CLINICAL NEUROLOGY AND NEUROSURGERY
(2023)
Article
Medicine, General & Internal
Philipp Krauss, Stefan Motov, Maximilian Niklas Bonk, Andrea Prescher, Jasmin Scorzin, Mohammad Mehdi Hajiabadi, Dirk Michael Schulte, Bjoern Sommer, Marcel Seiz-Rosenhagen, Rezvan Ahmadi, Jaroslaw Maciaczyk, Jens Lehmberg, Ehab Shiban
Summary: This study compares high-frequency neuromodulation with spinal instrumentation surgery for the treatment of patients with PSPS2. The study aims to provide high-level evidence for the commonly used treatment options in this severely disabling condition by using comprehensive assessment measures such as ODI, VAS, SF-36, EuroQOL5D, and excluding certain patient conditions.
Article
Medicine, Research & Experimental
Iulia-Sevastiana Pastor, Lacrimioara Perju Dumbrava, Costel Siserman, Horatiu Stan, Ioana Para, Ioan Stefan Florian
Summary: This study aimed to assess predictive factors of 30-day mortality in patients with acute subdural hematoma (ASDH) after surgical intervention for traumatic brain injury (TBI). Factors independently linked to mortality included a Glasgow score ≤12 and a midline shift >7 mm, while brain herniation and intraparenchymal hematoma were associated with a higher probability of death. The type of neurosurgery performed was not an independent predictor, but craniectomy was associated with higher mortality.
EXPERIMENTAL AND THERAPEUTIC MEDICINE
(2021)
Article
Medicine, General & Internal
Yi Mao, Wangsheng Wu, Junchao Zhang, Zhou Ye
Summary: This study aimed to develop a prediction model to assess the risk of adjacent vertebral compression fractures (AVCFs) after percutaneous kyphoplasty (PKP) surgery. Retrospective chart reviews were conducted on patients who underwent PKP surgery at Quzhou People's Hospital from March 2017 to May 2019. The study identified several predictors for AVCF risk, including gender, age, number of surgical vertebrae, cement volume, bone mineral density, diabetes, hypertension, bone cement leakage, duration of anti-osteoporosis treatment after surgery, and TL junction.
Article
Public, Environmental & Occupational Health
Han Xie, Jingxuan Wei, Zhengliang Ma, Weihong Ge
Summary: The aim of this study was to investigate the predictive factors of acute pain after open radical gastrectomy (OG) for gastric cancer patients. The results showed that total gastrectomy, AJCC TNM stage, BMI, distant metastasis, and intraoperative transfusion were significant predictive factors for acute pain after OG in gastric cancer patients.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Multidisciplinary Sciences
Niccolo Castellino, Maurizio Battaglia Parodi, Andrea Russo, Mario Damiano Toro, Matteo Fallico, Vincenza Bonfiglio, Agatino Davide Maugeri, Teresio Avitabile, Antonio Longo
Summary: This prospective study investigated the morphological changes of myopic choroidal neovascularization (mCNV) after treatment with anti-vascular endothelial growth factor and identified potential predictive features of the final best-corrected visual acuity (BCVA). The study found that immature CNV was usually smaller, required fewer treatments, and had better visual acuity improvement compared to mature CNV. Subretinal fibrosis was associated with lower final BCVA. Baseline immature pattern and baseline BCVA were predictive of final BCVA. Multimodal imaging, including OCTA, was useful in monitoring mCNV changes during treatment.
SCIENTIFIC REPORTS
(2022)
Article
Anesthesiology
Alp Eren Celenlioglu, Ender Sir
Summary: This study aimed to identify predictive factors affecting the success of ganglion impar block in treating chronic coccygodynia. The study found that prolonged symptom duration and the presence of permanent subluxation were associated with a decrease likelihood of treatment success.
REGIONAL ANESTHESIA AND PAIN MEDICINE
(2022)
Article
Chemistry, Multidisciplinary
Andrea Martinez-Arcos, Alejandro Lopez-Prieto, Lorena Rodriguez-Lopez, Benita Perez-Cid, Xanel Vecino, Ana Belen Moldes, Jose Manuel Cruz
Summary: The research demonstrated that the biosurfactant extracted from corn steep liquor not only has surfactant capacity and antimicrobial activity, but can also serve as a natural preservative for fruits. Surface analysis revealed that the biosurfactant could reduce roughness, shape changes, and increase hydrophobicity of fruit surfaces.
APPLIED SCIENCES-BASEL
(2021)
Article
Clinical Neurology
Mohammad Sadegh Masoudi, Reza Taheri, Sina Zoghi
Summary: This study aimed to identify factors predicting tracheostomy requirement in children diagnosed with posterior fossa medulloblastoma postoperatively. Factors such as brainstem compression, absence of gag reflex, and extent of tumor resection were found to be associated with a higher likelihood of requiring tracheostomy. Total tumor resection could potentially prevent the expensive and stressful postoperative morbidity of tracheostomy.
WORLD NEUROSURGERY
(2021)
Article
Clinical Neurology
Pernille Linde Jellestad, Louise Ninett Carlsen, Maria Lurenda Westergaard, Signe Bruun Munksgaard, Lars Bendtsen, Miguel Lainez, Ricardo Fadic, Zaza Katsarava, Maria Teresa Goicochea, Santiago Spadafora, Rigmor Hojland Jensen, Giuseppe Nappi, Cristina Tassorelli, Grazia Sances, Marta Allena, Marina Rapsch, Beatriz Lopez, Beatriz Shand
Article
Clinical Neurology
L. Bendtsen, J. M. Zakrzewska, J. Abbott, M. Braschinsky, G. Di Stefano, A. Donnet, P. K. Eide, P. R. L. Leal, S. Maarbjerg, A. May, T. Nurmikko, M. Obermann, T. S. Jensen, G. Cruccu
EUROPEAN JOURNAL OF NEUROLOGY
(2019)
Article
Clinical Neurology
Tone Bruvik Heinskou, Stine Maarbjerg, Frauke Wolfram, Per Rochat, Jannick Brennum, Jes Olesen, Lars Bendtsen
JOURNAL OF HEADACHE AND PAIN
(2019)
Article
Clinical Neurology
Louise Ninett Carlsen, Signe Bruun Munksgaard, Mia Nielsen, Ida Maria Storm Engelstoft, Maria Lurenda Westergaard, Lars Bendtsen, Rigmor Hojland Jensen
Review
Clinical Neurology
Cesar Fernandez-de-las-Penas, Gustavo Plaza-Manzano, Marcos J. Navarro-Santana, Jes Olesen, Rigmor H. Jensen, Lars Bendtsen
Summary: This meta-analysis found low to moderate evidence supporting the presence of pressure pain hypersensitivity in trigeminal and neck areas in tension-type headache patients compared to controls. Sensitivity to pressure pain was widespread only in chronic tension-type headache, not in episodic cases.
Review
Clinical Neurology
Lars Bendtsen, Joanna Maria Zakrzewska, Tone Bruvik Heinskou, Mojgan Hodaie, Paulo Roberto Lacerda Leal, Turo Nurmikko, Mark Obermann, Giorgio Cruccu, Stine Maarbjerg
Article
Clinical Neurology
Navid Noory, Emil Andonov Smilkov, Jette Lautrup Frederiksen, Tone Bruvik Heinskou, Anne Sofie Schott Andersen, Lars Bendtsen, Stine Maarbjerg
Summary: The primary cause of trigeminal neuralgia secondary to multiple sclerosis is demyelination along the intrapontine trigeminal afferents. In contrast to classical trigeminal neuralgia, neurovascular contact does not play a role in the etiology of trigeminal neuralgia secondary to multiple sclerosis. Microvascular decompression should generally not be offered to patients with this condition.
Article
Anesthesiology
Carolien Rouw, Signe B. Munksgaard, Ida M. S. Engelstoft, Mia Nielsen, Maria L. Westergaard, Rigmor H. Jensen, Lars Bendtsen, Louise N. Carlsen
Summary: Withdrawal combined with preventive medication from the start is the most effective treatment strategy for medication overuse headache (MOH) patients, reducing dependence-like behavior the most. While preventive treatment without withdrawal may initially be considered more feasible, there were no significant differences in feasibility between the three treatment arms during long-term follow-up.
EUROPEAN JOURNAL OF PAIN
(2021)
Article
Clinical Neurology
Henrik W. Schytz, Faisal M. Amin, Rigmor H. Jensen, Louise Carlsen, Stine Maarbjerg, Nunu Lund, Karen Aegidius, Lise L. Thomsen, Flemming W. Bach, Dagmar Beier, Hanne Johansen, Jakob M. Hansen, Helge Kasch, Signe B. Munksgaard, Lars Poulsen, Per Schmidt Sorensen, Peter T. Schmidt-Hansen, Vlasta V. Cvetkovic, Messoud Ashina, Lars Bendtsen
Summary: The Danish Headache Society has launched a third version of the guidelines for the diagnosis, organization, and treatment of the most common types of headaches and facial pain, aiming to educate and advocate for the needs of patients. The guidelines provide information on examining and diagnosing headache patients, organizing headache treatment, as well as characteristics, diagnosis, and treatment for each common type of headache disorders.
JOURNAL OF HEADACHE AND PAIN
(2021)
Review
Clinical Neurology
Stine Maarbjerg, Rafael Benoliel
Summary: This narrative review provides updated information on the new classification, clinical signs, and management of trigeminal neuralgia (TN). The new TN classification is based on reliable clinical data, imaging, and neurophysiologic studies, improving clinicians' ability to choose appropriate management options. However, there is a lack of effective, safe drugs for TN management and sparse data on neurosurgical options.