Cryptosporidium parvum disrupts intestinal epithelial barrier function via altering expression of key tight junction and adherens junction proteins

Innate immune responses play a key role in controlling infection of the intestinal epithelium by Cryptosporidium

(2017) Fabrice Laurent et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

The mucosal barrier at a glance

(2017) Marion M. France et al.   JOURNAL OF CELL SCIENCE

New Tools for Cryptosporidium Lead to New Hope for Cryptosporidiosis

(2017) Honorine D. Ward   TRENDS IN PARASITOLOGY

Lactobacillus acidophilus counteracts inhibition of NHE3 and DRA expression and alleviates diarrheal phenotype in mice infected with Citrobacter rodentium

(2016) Anoop Kumar et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Tight junctions in inflammatory bowel diseases and inflammatory bowel disease associated colorectal cancer

(2016) Jonathan Landy et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Addressing Cryptosporidium Infection among Young Children in Low-Income Settings: The Crucial Role of New and Existing Drugs for Reducing Morbidity and Mortality

(2016) David A. Shoultz et al.   PLoS Neglected Tropical Diseases

Infection Strategies of Intestinal Parasite Pathogens and Host Cell Responses

(2016) Bruno M. Di Genova et al.   Frontiers in Microbiology

New developments in Cryptosporidium research

(2015) Una Ryan et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

A review of the global burden, novel diagnostics, therapeutics, and vaccine targets for cryptosporidium

(2015) William Checkley et al.   LANCET INFECTIOUS DISEASES

Pathogen-specific burdens of community diarrhoea in developing countries: a multisite birth cohort study (MAL-ED)

(2015) James A Platts-Mills et al.   Lancet Global Health

Lactobacillus acidophilus attenuates downregulation of DRA function and expression in inflammatory models

(2014) Varsha Singh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Defects in the adherens junction complex (E-cadherin/ β-catenin) in inflammatory bowel disease

(2014) Shameer Mehta et al.   CELL AND TISSUE RESEARCH

Effect of Wild-Type Shigella Species and Attenuated Shigella Vaccine Candidates on Small Intestinal Barrier Function, Antigen Trafficking, and Cytokine Release

(2014) Maria Fiorentino et al.   PLoS One

TNF-α Modulation of Intestinal Epithelial Tight Junction Barrier Is Regulated by ERK1/2 Activation of Elk-1

(2013) Rana Al-Sadi et al.   AMERICAN JOURNAL OF PATHOLOGY

Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study

(2013) Karen L Kotloff et al.   LANCET

Claudins and the Modulation of Tight Junction Permeability

(2013) Dorothee Günzel et al.   PHYSIOLOGICAL REVIEWS

Salmonella Infection Upregulates the Leaky Protein Claudin-2 in Intestinal Epithelial Cells

(2013) Yong-guo Zhang et al.   PLoS One

Burden of disease from cryptosporidiosis

(2012) Debbie-Ann T. Shirley et al.   CURRENT OPINION IN INFECTIOUS DISEASES

New advances in the pathophysiology of intestinal ion transport and barrier function in diarrhea and the impact on therapy

(2012) Kazi Mirajul Hoque et al.   Expert Review of Anti-Infective Therapy

Adherens junctions as targets of microorganisms: A focus onHelicobacter pylori

(2012) Angela Margarida Costa et al.   FEBS LETTERS

Proteasome Inhibition of Pathologic Shedding of Enterocytes to Defend Barrier Function Requires X-Linked Inhibitor of Apoptosis Protein and Nuclear Factor κB

(2012) Derek M. Foster et al.   GASTROENTEROLOGY

Campylobacter jejuni Disrupts Protective Toll-Like Receptor 9 Signaling in Colonic Epithelial Cells and Increases the Severity of Dextran Sulfate Sodium-Induced Colitis in Mice

(2012) Jennifer R. O'Hara et al.   INFECTION AND IMMUNITY

Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium

(2011) Toshiro Sato et al.   GASTROENTEROLOGY

Cytoskeletal Regulation of Epithelial Barrier Function During Inflammation

(2010) Andrei I. Ivanov et al.   AMERICAN JOURNAL OF PATHOLOGY

A Key Role for E-cadherin in Intestinal Homeostasis and Paneth Cell Maturation

(2010) Marlon R. Schneider et al.   PLoS One

Mechanisms and Functional Implications of Intestinal Barrier Defects

(2009) Le Shen et al.   DIGESTIVE DISEASES

Mechanisms of cross-talk between the ubiquitin-proteasome and autophagy-lysosome systems

(2009) Viktor I. Korolchuk et al.   FEBS LETTERS

Intestinal barrier function: Molecular regulation and disease pathogenesis

(2009) Katherine R. Groschwitz et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Tight junctions as targets of infectious agents

(2008) Julian A. Guttman et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Cytokine regulation of tight junctions

(2008) Christopher T. Capaldo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Enteric infection meets intestinal function: how bacterial pathogens cause diarrhoea

(2008) V. K. Viswanathan et al.   NATURE REVIEWS MICROBIOLOGY