A complex of the ubiquitin ligase TRIM32 and the deubiquitinase USP7 balances the level of c-Myc ubiquitination and thereby determines neural stem cell fate specification

HAUSP deubiquitinates and stabilizes N-Myc in neuroblastoma

(2016) Omid Tavana et al.   NATURE MEDICINE

The RNA helicase DDX6 regulates cell-fate specification in neural stem cells via miRNAs

(2015) Sarah Nicklas et al.   NUCLEIC ACIDS RESEARCH

TRIM32 modulates pluripotency entry and exit by directly regulating Oct4 stability

(2015) Lamia’a Bahnassawy et al.   Scientific Reports

Trim32 Facilitates Degradation of MYCN on Spindle Poles and Induces Asymmetric Cell Division in Human Neuroblastoma Cells

(2014) H. Izumi et al.   CANCER RESEARCH

Sox2, a key factor in the regulation of pluripotency and neural differentiation

(2014) Shuchen Zhang   World Journal of Stem Cells

Regulatory feedback loop between TP73 and TRIM32

(2013) L Gonzalez-Cano et al.   Cell Death & Disease

TRIM32-dependent transcription in adult neural progenitor cells regulates neuronal differentiation

(2013) A-L Hillje et al.   Cell Death & Disease

MYC, Metabolism, Cell Growth, and Tumorigenesis

(2013) C. V. Dang   Cold Spring Harbor Perspectives in Medicine

The Ubiquitin Code

(2012) David Komander et al.   Annual Review of Biochemistry

TRIM32 Regulates Skeletal Muscle Stem Cell Differentiation and Is Necessary for Normal Adult Muscle Regeneration

(2012) Sarah Nicklas et al.   PLoS One

Functional interactions between ubiquitin E2 enzymes and TRIM proteins

(2011) Luisa M. Napolitano et al.   BIOCHEMICAL JOURNAL

The Multifaceted Roles of USP7: New Therapeutic Opportunities

(2011) Benjamin Nicholson et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Roles of HAUSP-mediated p53 regulation in central nervous system development

(2011) N Kon et al.   CELL DEATH AND DIFFERENTIATION

Deubiquitylase HAUSP stabilizes REST and promotes maintenance of neural progenitor cells

(2011) Zhi Huang et al.   NATURE CELL BIOLOGY

Adult Neurogenesis in the Mammalian Brain: Significant Answers and Significant Questions

(2011) Guo-li Ming et al.   NEURON

An Oct4-Centered Protein Interaction Network in Embryonic Stem Cells

(2010) Debbie L.C. van den Berg et al.   Cell Stem Cell

Neural stem cell systems: physiological players or in vitro entities?

(2010) Luciano Conti et al.   NATURE REVIEWS NEUROSCIENCE

The TRIM-NHL Protein TRIM32 Activates MicroRNAs and Prevents Self-Renewal in Mouse Neural Progenitors

(2009) Jens C. Schwamborn et al.   CELL

Breaking the chains: structure and function of the deubiquitinases

(2009) David Komander et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mechanisms and Functional Implications of Adult Neurogenesis

(2008) Chunmei Zhao et al.   CELL

Myc's broad reach

(2008) M. Eilers et al.   GENES & DEVELOPMENT

SCFβ-TRCP controls oncogenic transformation and neural differentiation through REST degradation

(2008) Thomas F. Westbrook et al.   NATURE

Control of chromosome stability by the β-TrCP–REST–Mad2 axis

(2008) Daniele Guardavaccaro et al.   NATURE