Oroxylin A, a natural compound, mitigates the negative effects of TNFα-treated acute myelogenous leukemia cells

Acute Myeloid Leukemia

(2017) Margaret R. O'Donnell et al.   Journal of the National Comprehensive Cancer Network

Sensitizing acute myeloid leukemia cells to induced differentiation by inhibiting the RIP1/RIP3 pathway

(2016) J Xin et al.   LEUKEMIA

Genomic Classification and Prognosis in Acute Myeloid Leukemia

(2016) Elli Papaemmanuil et al.   NEW ENGLAND JOURNAL OF MEDICINE

Correlation between p65 and TNF-α in patients with acute myelocytic leukemia

(2015) QIAO-MEI DONG et al.   Oncology Letters

Oroxylin A exerts anti-inflammatory activity on lipopolysaccharide-induced mouse macrophage via Nrf2/ARE activation

(2014) Ming Ye et al.   Biochemistry and Cell Biology

Co-inhibition of NF-κB and JNK is synergistic in TNF-expressing human AML

(2014) Andrew Volk et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Oroxylin A has therapeutic potential in acute myelogenous leukemia by dual effects targeting PPARγ and RXRα

(2013) Hui Hui et al.   INTERNATIONAL JOURNAL OF CANCER

Oroxylin A Induces BDNF Expression on Cortical Neurons through Adenosine A2AReceptor Stimulation: A Possible Role in Neuroprotection

(2012) Se-Jin Jeon et al.   Biomolecules & Therapeutics

TIS21/BTG2/PC3 enhances downregulation of c-Myc during differentiation of HL-60 cells by activating Erk1/2 and inhibiting Akt in response to all-trans-retinoic acid

(2012) Muhammad Imran et al.   EUROPEAN JOURNAL OF CANCER

Inhibition of PCGF2 enhances granulocytic differentiation of acute promyelocytic leukemia cell line HL-60 via induction of HOXA7

(2011) Sungsin Jo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Activation of PKC-e counteracts maturation and apoptosis of HL-60 myeloid leukemic cells in response to TNF family members

(2011) A. Gonelli et al.   EUROPEAN JOURNAL OF HISTOCHEMISTRY

Targeting the translational apparatus to improve leukemia therapy: roles of the PI3K/PTEN/Akt/mTOR pathway

(2011) A M Martelli et al.   LEUKEMIA

Kuromoji (Lindera umbellata) essential oil-induced apoptosis and differentiation in human leukemia HL-60 cells

(2011) HAYATO MAEDA et al.   Experimental and Therapeutic Medicine

NSAID Sulindac and Its Analog Bind RXRα and Inhibit RXRα-Dependent AKT Signaling

(2010) Hu Zhou et al.   CANCER CELL

CD44-ligation induces, through ERK1/2 pathway, synthesis of cytokines TNF-α and IL-6 required for differentiation of THP-1 monoblastic leukemia cells

(2010) S Bourcier et al.   LEUKEMIA

Retinoid X receptors: common heterodimerization partners with distinct functions

(2010) Philippe Lefebvre et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Monocytic differentiation of leukemic HL-60 cells induced by co-treatment with TNF-α and MK886 requires activation of pro-apoptotic machinery

(2009) Jiřina Procházková et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Oroxylin A inhibits angiogenesis through blocking vascular endothelial growth factor-induced KDR/Flk-1 phosphorylation

(2009) Ying Gao et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Involvement of p53 in oroxylin A-induced apoptosis in cancer cells

(2009) Rong Mu et al.   MOLECULAR CARCINOGENESIS

Death-associated protein 5 (DAP5/p97/NAT1) contributes to retinoic acid-induced granulocytic differentiation and arsenic trioxide-induced apoptosis in acute promyelocytic leukemia

(2008) Bulent Ozpolat et al.   APOPTOSIS

The prognostic significance of cytokine levels in newly diagnosed acute myeloid leukemia and high-risk myelodysplastic syndromes

(2008) Apostolia Maria Tsimberidou et al.   CANCER

Inhibition of DNA Methyltransferase Activates Tumor Necrosis Factor  -Induced Monocytic Differentiation in Acute Myeloid Leukemia Cells

(2008) A. Laurenzana et al.   CANCER RESEARCH

Wogonin induces the granulocytic differentiation of human NB4 promyelocytic leukemia cells and up-regulates phospholipid scramblase 1 gene expression

(2008) Kun Zhang et al.   CANCER SCIENCE

Retinoid X receptor α is highly phosphorylated in retinoic acid-resistant HL-60R cells and the combination of 9-cis retinoic acid plus MEK inhibitor induces apoptosis in the cells

(2007) Nobuhiro Kanemura et al.   LEUKEMIA RESEARCH