Exosomes serve as nanoparticles to suppress tumor growth and angiogenesis in gastric cancer by delivering hepatocyte growth factor siRNA

Cell-derived microvesicles mediate the delivery of miR-29a/c to suppress angiogenesis in gastric carcinoma

(2016) Haiyang Zhang et al.   CANCER LETTERS

Lipid nanoparticles for targeted siRNA delivery – going from bench to bedside

(2016) Victor Kotelianski et al.   International Journal of Nanomedicine

Gene of the month:HGF

(2016) Ana Belen Fajardo-Puerta et al.   JOURNAL OF CLINICAL PATHOLOGY

Current Molecular Targeted Therapy in Advanced Gastric Cancer: A Comprehensive Review of Therapeutic Mechanism, Clinical Trials, and Practical Application

(2016) Kaichun Li et al.   Gastroenterology Research and Practice

Signal transduction and downregulation of C-MET in HGF stimulated low and highly metastatic human osteosarcoma cells

(2015) Knut Husmann et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

HGF and c-Met in pathogenesis of endometrial carcinoma

(2015) Hongbo Wang   Frontiers in Bioscience-Landmark

Quercetin inhibits HGF/c-Met signaling and HGF-stimulated melanoma cell migration and invasion

(2015) Hui-Hui Cao et al.   Molecular Cancer

Knocking down disease: a progress report on siRNA therapeutics

(2015) Anders Wittrup et al.   NATURE REVIEWS GENETICS

Ectosomes and exosomes: shedding the confusion between extracellular vesicles

(2015) Emanuele Cocucci et al.   TRENDS IN CELL BIOLOGY

Curcumin mediates reversion of HGF-induced epithelial-mesenchymal transition via inhibition of c-Met expression in DU145 cells

(2015) HUI-JUN HU et al.   Oncology Letters

Targeted exosome-mediated delivery of opioid receptor Mu siRNA for the treatment of morphine relapse

(2015) Yuchen Liu et al.   Scientific Reports

RhoGDI2 is associated with HGF-mediated tumor invasion through VEGF in stomach cancer

(2014) Sung Ae Koh et al.   CLINICAL & EXPERIMENTAL METASTASIS

Combination Strategy Targeting VEGF and HGF/c-met in Human Renal Cell Carcinoma Models

(2014) E. Ciamporcero et al.   MOLECULAR CANCER THERAPEUTICS

Clinical impact of the HGF/MET pathway activation in patients with advanced gastric cancer treated with palliative chemotherapy

(2014) F Graziano et al.   PHARMACOGENOMICS JOURNAL

Bioinspired Exosome-Mimetic Nanovesicles for Targeted Delivery of Chemotherapeutics to Malignant Tumors

(2013) Su Chul Jang et al.   ACS Nano

MicroRNA-26a suppresses angiogenesis in human hepatocellular carcinoma by targeting hepatocyte growth factor-cMet pathway

(2013) Xin Yang et al.   HEPATOLOGY

A phase II trial of a selective c-Met inhibitor tivantinib (ARQ 197) monotherapy as a second- or third-line therapy in the patients with metastatic gastric cancer

(2013) Yoon-Koo Kang et al.   INVESTIGATIONAL NEW DRUGS

Exosomes and the Emerging Field of Exosome-Based Gene Therapy

(2012) Aisling O’Loughlin et al.   CURRENT GENE THERAPY

Hepatocyte growth factor stimulated angiogenesis without inflammation: Differential actions between hepatocyte growth factor, vascular endothelial growth factor and basic fibroblast growth factor

(2012) Toshihiro Kaga et al.   VASCULAR PHARMACOLOGY

Clinical Correlations and Prognostic Relevance of Tissue Angiogenic Factors in Patients with Gastric Cancer

(2011) Y. Mohri et al.   CLINICAL ONCOLOGY

Microvesicles and exosomes: Opportunities for cell-derived membrane vesicles in drug delivery

(2011) Susan M. van Dommelen et al.   JOURNAL OF CONTROLLED RELEASE

MicroRNA-155Regulates Cell Survival, Growth, and Chemosensitivity by TargetingFOXO3ain Breast Cancer

(2010) William Kong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Secreted Monocytic miR-150 Enhances Targeted Endothelial Cell Migration

(2010) Yujing Zhang et al.   MOLECULAR CELL

VEGF Secretion by Neuroendocrine Tumor Cells Is Inhibited by Octreotide and by Inhibitors of the PI3K/AKT/mTOR Pathway

(2010) Karine Villaume et al.   NEUROENDOCRINOLOGY

Nanomedicine based approaches for the delivery of siRNA in cancer

(2009) B. Ozpolat et al.   JOURNAL OF INTERNAL MEDICINE

Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity

(2009) Derrick J. Gibbings et al.   NATURE CELL BIOLOGY