FBW7 is associated with prognosis, inhibits malignancies and enhances temozolomide sensitivity in glioblastoma cells

The bad seed gardener: Deubiquitinases in the cancer stem-cell signaling network and therapeutic resistance

(2017) Guan-Zhong Qiu et al.   PHARMACOLOGY & THERAPEUTICS

FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma

(2016) Aldwin Suryo Rahmanto et al.   EMBO JOURNAL

Fbxw7 Tumor Suppressor

(2016) Jun Cao et al.   MEDICINE

ERK kinase phosphorylates and destabilizes the tumor suppressor FBW7 in pancreatic cancer

(2015) Shunrong Ji et al.   CELL RESEARCH

Fbxw7 regulates hepatocellular carcinoma migration and invasion via Notch1 signaling pathway

(2015) XING WANG et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Aberrant regulation of FBW7 in cancer

(2015) Lixia Wang et al.   Oncotarget

The Cdk inhibitor flavopiridol enhances temozolomide-induced cytotoxicity in human glioma cells

(2013) Takuro Hayashi et al.   JOURNAL OF NEURO-ONCOLOGY

Knockdown of AKT2 expression by RNA interference inhibits proliferation, enhances apoptosis, and increases chemosensitivity to the anticancer drug VM-26 in U87 glioma cells

(2012) Yong Cui et al.   BRAIN RESEARCH

FBXW7 is involved in Aurora B degradation

(2012) Chieh-Lin Teng et al.   CELL CYCLE

Distinct molecular mechanisms of acquired resistance to temozolomide in glioblastoma cells

(2012) Caroline Happold et al.   JOURNAL OF NEUROCHEMISTRY

Key concepts in glioblastoma therapy

(2012) Jiri Bartek et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

SCFFBW7 regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction

(2011) Hiroyuki Inuzuka et al.   NATURE

Exciting New Advances in Neuro-Oncology: The Avenue to a Cure for Malignant Glioma

(2010) E. G. Van Meir et al.   CA-A CANCER JOURNAL FOR CLINICIANS

The tumour suppressor C/EBPδ inhibits FBXW7 expression and promotes mammary tumour metastasis

(2010) Kuppusamy Balamurugan et al.   EMBO JOURNAL

Perifosine Inhibits Mammalian Target of Rapamycin Signaling through Facilitating Degradation of Major Components in the mTOR Axis and Induces Autophagy

(2009) L. Fu et al.   CANCER RESEARCH