c-Src inhibitor selectively inhibits triple-negative breast cancer overexpressed Vimentin in vitro and in vivo

Molecular alterations in triple-negative breast cancer—the road to new treatment strategies

(2017) Carsten Denkert et al.   LANCET

The TRAIL receptor agonist drozitumab targets basal B triple-negative breast cancer cells that express vimentin and Axl

(2016) Jennifer L. Dine et al.   BREAST CANCER RESEARCH AND TREATMENT

Impact of Expression of Vimentin and Axl in Breast Cancer

(2016) Kimihiro Tanaka et al.   Clinical Breast Cancer

UM-164: A Potent c-Src/p38 Kinase Inhibitor with In Vivo Activity against Triple-Negative Breast Cancer

(2016) R. A. Gilani et al.   CLINICAL CANCER RESEARCH

Novel roles of Src in cancer cell epithelial-to-mesenchymal transition, vascular permeability, microinvasion and metastasis

(2016) Ami Patel et al.   LIFE SCIENCES

Targeting Src in endometriosis-associated ovarian cancer

(2016) R Manek et al.   Oncogenesis

Vimentin–ERK Signaling Uncouples Slug Gene Regulatory Function

(2015) Reetta Virtakoivu et al.   CANCER RESEARCH

Design, Synthesis, and Structure–Activity Relationship Studies of 3-(Phenylethynyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine Derivatives as a New Class of Src Inhibitors with Potent Activities in Models of Triple Negative Breast Cancer

(2015) Chun-Hui Zhang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Cyr61 as mediator of Src signaling in triple negative breast cancer cells

(2015) María Pilar Sánchez-Bailón et al.   Oncotarget

Transmembrane-Bound IL-15–Promoted Epithelial-Mesenchymal Transition in Renal Cancer Cells Requires the Src-Dependent Akt/GSK-3β/β-Catenin Pathway

(2015) Huaqin Yuan et al.   NEOPLASIA

Molecularly targeted therapies for metastatic triple-negative breast cancer

(2013) Soley Bayraktar et al.   BREAST CANCER RESEARCH AND TREATMENT

Breast cancer statistics, 2013

(2013) Carol DeSantis et al.   CA-A CANCER JOURNAL FOR CLINICIANS

c-Src Modulates Estrogen-Induced Stress and Apoptosis in Estrogen-Deprived Breast Cancer Cells

(2013) P. Fan et al.   CANCER RESEARCH

P-cadherin and vimentin are useful basal markers in breast cancers

(2013) Julia Y.S. Tsang et al.   HUMAN PATHOLOGY

Vimentin DNA methylation predicts survival in breast cancer

(2012) Jacob Ulirsch et al.   BREAST CANCER RESEARCH AND TREATMENT

Modulating therapeutic effects of the c-Src inhibitor via oestrogen receptor and human epidermal growth factor receptor 2 in breast cancer cell lines

(2012) Ping Fan et al.   EUROPEAN JOURNAL OF CANCER

The clonal and mutational evolution spectrum of primary triple-negative breast cancers

(2012) Sohrab P. Shah et al.   NATURE

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

Metastatic Progression of Prostate Cancer and E-Cadherin

(2011) Aaron P. Putzke et al.   AMERICAN JOURNAL OF PATHOLOGY

Phase II study of single-agent bosutinib, a Src/Abl tyrosine kinase inhibitor, in patients with locally advanced or metastatic breast cancer pretreated with chemotherapy

(2011) M. Campone et al.   ANNALS OF ONCOLOGY

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Phase II Trial of Saracatinib (AZD0530), an Oral SRC-inhibitor for the Treatment of Patients with Hormone Receptor-negative Metastatic Breast Cancer

(2011) Ayca Gucalp et al.   Clinical Breast Cancer

Dasatinib as a Single Agent in Triple-Negative Breast Cancer: Results of an Open-Label Phase 2 Study

(2011) R. S. Finn et al.   CLINICAL CANCER RESEARCH

Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies

(2011) Brian D. Lehmann et al.   JOURNAL OF CLINICAL INVESTIGATION

Vimentin organization modulates the formation of lamellipodia

(2011) Brian T. Helfand et al.   MOLECULAR BIOLOGY OF THE CELL

Simultaneous siRNA Targeting of Src and Downstream Signaling Molecules Inhibit Tumor Formation and Metastasis of a Human Model Breast Cancer Cell Line

(2011) Jeffrey D. Bjorge et al.   PLoS One

Triple-negative breast cancer: disease entity or title of convenience?

(2010) Lisa Carey et al.   Nature Reviews Clinical Oncology

Triple-Negative Breast Cancer

(2010) William D. Foulkes et al.   NEW ENGLAND JOURNAL OF MEDICINE

Biology, Metastatic Patterns, and Treatment of Patients with Triple-Negative Breast Cancer

(2009) Carey K. Anders et al.   Clinical Breast Cancer

Search for New Treatments Intensifies for Triple-Negative Breast Cancer

(2009) Vicki Brower   JNCI-Journal of the National Cancer Institute

Targeting Src in breast cancer

(2008) R. S. Finn   ANNALS OF ONCOLOGY