Naturally produced type I IFNs enhance human myeloid dendritic cell maturation and IL-12p70 production and mediate elevated effector functions in innate and adaptive immune cells

Type I Interferons Modulate CD8 + T Cell Immunity to mRNA Vaccines

(2017) Ans De Beuckelaer et al.   TRENDS IN MOLECULAR MEDICINE

Harnessing RNA sequencing for global, unbiased evaluation of two new adjuvants for dendritic-cell immunotherapy

(2017) Till S.M. Mathan et al.   Oncotarget

Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy

(2016) Lena M. Kranz et al.   NATURE

Antitumor dendritic cell–based vaccines: lessons from 20 years of clinical trials and future perspectives

(2016) João Constantino et al.   Translational Research

Functional Interplay between Type I and II Interferons Is Essential to Limit Influenza A Virus-Induced Tissue Inflammation

(2016) Sebastian A. Stifter et al.   PLoS Pathogens

Human blood myeloid and plasmacytoid dendritic cells cross activate each other and synergize in inducing NK cell cytotoxicity

(2016) Jasper J. P. van Beek et al.   OncoImmunology

Protamine-stabilized RNA as an ex vivo stimulant of primary human dendritic cell subsets

(2015) Annette E. Sköld et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Engineering monocyte-derived dendritic cells to secrete interferon-α enhances their ability to promote adaptive and innate anti-tumor immune effector functions

(2015) Yannick Willemen et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Human dendritic cell subsets and function in health and disease

(2015) Meredith O’Keeffe et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Effective Clinical Responses in Metastatic Melanoma Patients after Vaccination with Primary Myeloid Dendritic Cells

(2015) G. Schreibelt et al.   CLINICAL CANCER RESEARCH

Type I IFN-mediated synergistic activation of mouse and human DC subsets by TLR agonists

(2015) Martin Kreutz et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Differential effects of IFN-  on IL-12, IL-23, and IL-10 expression in TLR-stimulated dendritic cells

(2015) J.-H. Yen et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Dendritic Cell Cross Talk with Innate and Innate-like Effector Cells in Antitumor Immunity: Implications for DC Vaccination

(2014) Jasper J. P. van Beek et al.   CRITICAL REVIEWS IN IMMUNOLOGY

Crosstalk between dendritic cell subsets and implications for dendritic cell-based anticancer immunotherapy

(2014) Ghaith Bakdash et al.   Expert Review of Clinical Immunology

Brief Antigenic Stimulation Generates Effector CD8 T Cells with Low Cytotoxic Activity and High IL-2 Production

(2014) D. Usharauli et al.   JOURNAL OF IMMUNOLOGY

Paradigm Shift in Dendritic Cell-Based Immunotherapy: From in vitro Generated Monocyte-Derived DCs to Naturally Circulating DC Subsets

(2014) Florian Wimmers et al.   Frontiers in Immunology

Natural Human Plasmacytoid Dendritic Cells Induce Antigen-Specific T-Cell Responses in Melanoma Patients

(2013) J. Tel et al.   CANCER RESEARCH

IFN-  Induces APOBEC3G, F, and A in Immature Dendritic Cells and Limits HIV-1 Spread to CD4+ T Cells

(2013) V. Mohanram et al.   JOURNAL OF IMMUNOLOGY

Single-stranded DNA oligonucleotides inhibit TLR3-mediated responses in human monocyte-derived dendritic cells and in vivo in cynomolgus macaques

(2012) A. E. Skold et al.   BLOOD

Particle size and activation threshold: a new dimension of danger signaling

(2010) L. Rettig et al.   BLOOD

Human plasmacytoid dendritic cells are unresponsive to bacterial stimulation and require a novel type of cooperation with myeloid dendritic cells for maturation

(2009) D. Piccioli et al.   BLOOD

Reciprocal responsiveness to interleukin-12 and interferon-  specifies human CD8+ effector versus central memory T-cell fates

(2009) H. J. Ramos et al.   BLOOD

Direct Injection of Protamine-protected mRNA: Results of a Phase 1/2 Vaccination Trial in Metastatic Melanoma Patients

(2009) Benjamin Weide et al.   JOURNAL OF IMMUNOTHERAPY