Regulated intratumoral expression of IL-12 using a RheoSwitch Therapeutic System® (RTS®) gene switch as gene therapy for the treatment of glioma

Tumor infiltrating lymphocytes in early breast cancer

(2018) Giancarlo Pruneri et al.   BREAST

Immunotherapy of advanced melanoma by intratumoral injections of autologous, purified dendritic cells transduced with gene construct of interleukin-12, with dose-dependent expression under the control of an oral activator ligand.

(2017) D. J. Schwartzentruber et al.   JOURNAL OF CLINICAL ONCOLOGY

PD-1 Pathway Inhibitors: Changing the Landscape of Cancer Immunotherapy

(2017) Dawn E. Dolan et al.   Cancer Control

Ipilimumab and Bevacizumab in Glioblastoma

(2016) T. Carter et al.   CLINICAL ONCOLOGY

Regression of Glioblastoma after Chimeric Antigen Receptor T-Cell Therapy

(2016) Christine E. Brown et al.   NEW ENGLAND JOURNAL OF MEDICINE

A new anti-glioma therapy, AG119: pre-clinical assessment in a mouse GL261 glioma model

(2015) Rheal A. Towner et al.   BMC CANCER

CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2008-2012

(2015) Quinn T. Ostrom et al.   NEURO-ONCOLOGY

Glioblastoma Eradication Following Immune Checkpoint Blockade in an Orthotopic, Immunocompetent Model

(2015) D. A. Reardon et al.   Cancer Immunology Research

Tumour-infiltrating CD4+ and CD8+ lymphocytes as predictors of clinical outcome in glioma

(2014) S Han et al.   BRITISH JOURNAL OF CANCER

Localized interleukin-12 delivery for immunotherapy of solid tumours

(2013) Louis Z. Wei et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Intratumoral IL-12 combined with CTLA-4 blockade elicits T cell–mediated glioma rejection

(2013) Johannes vom Berg et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cytokine patterns in patients with cancer: a systematic review

(2013) Bodo E Lippitz   LANCET ONCOLOGY

Nivolumab plus Ipilimumab in Advanced Melanoma

(2013) Jedd D. Wolchok et al.   NEW ENGLAND JOURNAL OF MEDICINE

Recognition of Glioma Stem Cells by Genetically Modified T Cells Targeting EGFRvIII and Development of Adoptive Cell Therapy for Glioma

(2012) Richard A. Morgan et al.   HUMAN GENE THERAPY

Intratumoral IL-12 Gene Therapy Results in the Crosspriming of Tc1 Cells Reactive Against Tumor-associated Stromal Antigens

(2010) Xi Zhao et al.   MOLECULAR THERAPY

Conditional interleukin-12 gene therapy promotes safe and effective antitumor immunity

(2009) H Komita et al.   CANCER GENE THERAPY

Intratumoral rhIL-12 administration in head and neck squamous cell carcinoma patients induces B cell activation

(2008) Carla M.L. van Herpen et al.   INTERNATIONAL JOURNAL OF CANCER

An exploratory survival analysis of anti-angiogenic therapy for recurrent malignant glioma

(2008) Andrew D. Norden et al.   JOURNAL OF NEURO-ONCOLOGY