Effects of posaconazole (a strong CYP3A4 inhibitor), two new tablet formulations, and food on the pharmacokinetics of idasanutlin, an MDM2 antagonist, in patients with advanced solid tumors

Title
Effects of posaconazole (a strong CYP3A4 inhibitor), two new tablet formulations, and food on the pharmacokinetics of idasanutlin, an MDM2 antagonist, in patients with advanced solid tumors
Authors
Keywords
Idasanutlin, MDM2 antagonist, Drug–drug interaction, Food effect, Formulation change, External factors
Journal
CANCER CHEMOTHERAPY AND PHARMACOLOGY
Volume 81, Issue 3, Pages 529-537
Publisher
Springer Nature
Online
2018-01-24
DOI
10.1007/s00280-018-3521-z

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