Journal
CANCER AND METASTASIS REVIEWS
Volume 37, Issue 1, Pages 125-145Publisher
SPRINGER
DOI: 10.1007/s10555-017-9710-0
Keywords
Cancer biomarker; Precisionmedicine; omics; Accessible proteins
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The discovery of biomarkers able to detect cancer at an early stage, to evaluate its aggressiveness, and to predict the response to therapy remains a major challenge in clinical oncology and precision medicine. In this review, we summarize recent achievements in the discovery and development of cancer biomarkers. We also highlight emerging innovative methods in biomarker discovery and provide insights into the challenges faced in their evaluation and validation.
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