Chimaphilin inhibits human osteosarcoma cell invasion and metastasis through suppressing the TGF-β1-induced epithelial-to-mesenchymal transition markers via PI-3K/Akt, ERK1/2, and Smad signaling pathways

Chimaphilin inhibits proliferation and induces apoptosis in multidrug resistant osteosarcoma cell lines through insulin-like growth factor-I receptor (IGF-IR) signaling

(2015) Wan Daqian et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Negative pressure cavitation-microwave assisted preparation of extract of Pyrola incarnata Fisch. rich in hyperin, 2′-O-galloylhyperin and chimaphilin and evaluation of its antioxidant activity

(2015) Xiao-Hui Yao et al.   FOOD CHEMISTRY

Chimaphilin induces apoptosis in human breast cancer MCF-7 cells through a ROS-mediated mitochondrial pathway

(2014) Wei-Dong Ma et al.   FOOD AND CHEMICAL TOXICOLOGY

Modifiers of TGF-β1 effector function as novel therapeutic targets of pulmonary fibrosis

(2014) Chang-Min Lee et al.   KOREAN JOURNAL OF INTERNAL MEDICINE

TGF-β1 exposure induces epithelial to mesenchymal transition both in CSCs and non-CSCs of the A549 cell line, leading to an increase of migration ability in the CD133+ A549 cell fraction

(2013) V Tirino et al.   Cell Death & Disease

MiR-1 and miR-200 inhibit EMT via Slug-dependent and tumorigenesis via Slug-independent mechanisms

(2012) Y-N Liu et al.   ONCOGENE

A Novel Network Integrating a miRNA-203/SNAI1 Feedback Loop which Regulates Epithelial to Mesenchymal Transition

(2012) Michèle Moes et al.   PLoS One

Fyn mediates transforming growth factor-beta1-induced down-regulation of E-cadherin in human A549 lung cancer cells

(2011) An Na Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

SCUBE3 is an endogenous TGF-β receptor ligand and regulates the epithelial-mesenchymal transition in lung cancer

(2011) Y-Y Wu et al.   ONCOGENE

Transforming growth factor-β and the hallmarks of cancer

(2010) Maozhen Tian et al.   CELLULAR SIGNALLING

Osteosarcoma incidence and survival rates from 1973 to 2004

(2009) Lisa Mirabello et al.   CANCER

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

TGF-β3 and cancer: A review

(2009) H.G. Laverty et al.   CYTOKINE & GROWTH FACTOR REVIEWS

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

(2008) Philip A. Gregory et al.   NATURE CELL BIOLOGY

Antifungal and antioxidant activities of the phytomedicine pipsissewa, Chimaphila umbellata

(2007) Imelda J. Galván et al.   PHYTOCHEMISTRY