Luteolin ameliorates rat myocardial ischaemia-reperfusion injury through activation of peroxiredoxin II

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The IUPHAR/BPS Guide to PHARMACOLOGY in 2018: updates and expansion to encompass the new guide to IMMUNOPHARMACOLOGY

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Delayed coronary reperfusion is ineffective at impeding the dynamic increase in cardiac efferent sympathetic nerve activity following myocardial ischemia

(2016) Timothy M. Hall et al.   BASIC RESEARCH IN CARDIOLOGY

Luteolin protects the hippocampus against neuron impairments induced by kainic acid in rats

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Protective effect of luteolin on streptozotocin-induced diabetic renal damage in mice via the regulation of RIP140/NF-кB pathway and insulin signalling pathway

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(2015) John C McGrath et al.   BRITISH JOURNAL OF PHARMACOLOGY

Luteolin Exerts Cardioprotective Effects through Improving Sarcoplasmic Reticulum Ca2+-ATPase Activity in Rats during Ischemia/Reperfusion In Vivo

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Design, Synthesis, and Structure–Activity Relationship of Novel LSD1 Inhibitors Based on Pyrimidine–Thiourea Hybrids As Potent, Orally Active Antitumor Agents

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RPS12 increases the invasiveness in cervical cancer activated by c-Myc and inhibited by the dietary flavonoids luteolin and quercetin

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Luteolin Inhibits Ischemia/Reperfusion-Induced Myocardial Injury in Rats via Downregulation of microRNA-208b-3p

(2015) Chen Bian et al.   PLoS One

The cardioprotective effect of sodium tanshinone IIA sulfonate and the optimizing of therapeutic time window in myocardial ischemia/reperfusion injury in rats

(2014) Bo Wei et al.   ATHEROSCLEROSIS

Luteolin Attenuates Hepatic Steatosis and Insulin Resistance Through the Interplay Between the Liver and Adipose Tissue in Mice with Diet-Induced Obesity

(2014) Eun-Young Kwon et al.   DIABETES

Regulation of antioxidant system, lipids and fatty acid β-oxidation contributes to the cardioprotective effect of sodium tanshinone IIA sulphonate in isoproterenol-induced myocardial infarction in rats

(2013) Bo Wei et al.   ATHEROSCLEROSIS

Peroxiredoxin-1 from the Human Hookworm Ancylostoma ceylanicum Forms a Stable Oxidized Decamer and Is Covalently Inhibited by Conoidin A

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Triazole–Dithiocarbamate Based Selective Lysine Specific Demethylase 1 (LSD1) Inactivators Inhibit Gastric Cancer Cell Growth, Invasion, and Migration

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ERK/PP1a/PLB/SERCA2a and JNK Pathways Are Involved in Luteolin-Mediated Protection of Rat Hearts and Cardiomyocytes following Ischemia/Reperfusion

(2013) Xin Wu et al.   PLoS One

Protective Effect of Luteolin in Experimental Ischemic Stroke: Upregulated SOD1, CAT, Bcl-2 and Claudin-5, Down-Regulated MDA and Bax Expression

(2012) Huimin Qiao et al.   NEUROCHEMICAL RESEARCH

Luteolin Limits Infarct Size and Improves Cardiac Function after Myocardium Ischemia/Reperfusion Injury in Diabetic Rats

(2012) Dongdong Sun et al.   PLoS One

Targeting Cell Signaling and Apoptotic Pathways by Luteolin: Cardioprotective Role in Rat Cardiomyocytes Following Ischemia/Reperfusion

(2012) Tongda Xu et al.   Nutrients

Luteolin improves contractile function and attenuates apoptosis following ischemia–reperfusion in adult rat cardiomyocytes

(2011) Lingling Qi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Downregulation of the antioxidant protein peroxiredoxin 2 contributes to angiotensin II–mediated podocyte apoptosis

(2011) Hsiang-Hao Hsu et al.   KIDNEY INTERNATIONAL

Luteolin Inhibits Apoptosis and Improves Cardiomyocyte Contractile Function through the PI3K/Akt Pathway in Simulated Ischemia/Reperfusion

(2011) Fang Fang et al.   PHARMACOLOGY

Pathogenesis of Myocardial Ischemia-Reperfusion Injury and Rationale for Therapy

(2010) Aslan T. Turer et al.   AMERICAN JOURNAL OF CARDIOLOGY

Cardiomyocyte sulfonylurea receptor 2-KATP channel mediates cardioprotection and ST segment elevation

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Reduction of lipid accumulation in HepG2 Cells by luteolin is associated with activation of AMPK and Mitigation of oxidative stress

(2010) Jin-Feng Liu et al.   PHYTOTHERAPY RESEARCH

Typical 2-Cys peroxiredoxins - structures, mechanisms and functions

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Identification of conoidin A as a covalent inhibitor of peroxiredoxin II

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Reperfusion injury in acute myocardial infarction. From bench to cath lab. Part I: Basic considerations

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Protection of peroxiredoxin II on oxidative stress-induced cardiomyocyte death and apoptosis

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Redox signaling triggers protection during the reperfusion rather than the ischemic phase of preconditioning

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