Article
Cardiac & Cardiovascular Systems
Eerde H. Weening, Ali A. Al-Mubarak, Martin M. Dokter, Kenneth Dickstein, Chim C. Lang, Leong L. Ng, Marco Metra, Dirk J. van Veldhuisen, Daan J. Touw, Rudolf A. de Boer, Ron T. Gansevoort, Adriaan A. Voors, Stephan J. L. Bakker, Peter van der Meer, Nils Bomer
Summary: The study found that serum selenium levels are associated with the incidence of heart failure and metabolic syndrome. There are notable differences between males and females in food intake and micronutrient metabolism, possibly explaining different health outcomes.
CARDIOVASCULAR DIABETOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Josip Novoselec, Zeljka Klir Salavardic, Mislav Didara, Maja Novoselec, Rosemary Vukovic, Suzana Cavar, Zvonko Antunovic
Summary: This study investigated the effects of dietary selenium supplementation in late-gestation ewes on blood selenium concentrations and indicators of metabolic and antioxidant status in both ewes and their lambs. It was found that selenium supplementation significantly increased selenium concentration and antioxidant enzyme activity, while decreasing malondialdehyde concentration in both ewes and their lambs. The transfer of selenium from ewes to lambs during the suckling period was found to be more efficient when the diet was supplemented with organic selenium compared to inorganic selenium.
Article
Biochemistry & Molecular Biology
Natalia Druzhaeva, Alenka Nemec Svete, Gabrijela Tavcar-Kalcher, Janja Babic, Alojz Ihan, Katka Pohar, Uros Krapez, Aleksandra Domanjko Petric
Summary: This study investigated the effects of CoQ(10) supplementation in dogs with myxomatous mitral valve disease. Results showed that CoQ(10) supplementation had positive effects on certain blood parameters in dogs with congestive heart failure.
Article
Nutrition & Dietetics
Yili Hu, Xiaocui Chai, Jun Men, Shen Rao, Xin Cong, Shuiyuan Cheng, Zhixian Qiao
Summary: This study explored the metabolic effects and selenium utilization of selenomethionine supplementation in HepG2 cells under different methionine supply conditions. Results showed that selenomethionine promoted cell proliferation, selenoprotein transcription, and amino acid production while decreasing certain levels of substances regardless of methionine supply. Selenomethionine disturbed cell metabolism under methionine shortage, but this disturbance was alleviated with increasing methionine supply except for some changes.
Article
Chemistry, Multidisciplinary
Olivia M. Murton, G. William Dec, Robert E. Hillman, Maulik D. Majmudar, Johannes Steiner, John V. Guttag, Daryush D. Mehta
Summary: A potential application of this study is the monitoring of patients at risk for acute decompensated heart failure using non-invasive acoustic voice and speech biomarkers. The study found that after ADHF treatment, speakers showed more stable phonation, a creaky voice, faster speech rates, and longer phrases compared to their pre-treatment voices. This project advances the understanding of relevant voice and speech features for monitoring ADHF using speech biomarkers.
APPLIED SCIENCES-BASEL
(2023)
Article
Physiology
Alessia Cacciotti, Chiara Pappalettera, Francesca Miraglia, Lavinia Valeriani, Elda Judica, Paolo Maria Rossini, Fabrizio Vecchio
Summary: The aim of this study was to analyze the effects of CHF on brain activity through EEG complexity measures. The results showed significant differences between CHF patients and healthy elderly individuals in the total spectrum and theta frequency band of the EEG. Within the CHF group, correlations were found between EEG parameters and clinical data such as BNP and NYHA scores. These findings suggest similarities between EEG abnormalities in CHF and cognitive impairment.
Article
Cardiac & Cardiovascular Systems
JoAnn Lindenfeld, Richa Gupta, Luanda Grazette, Jean Marie Ruddy, Lana Tsao, Elizabeth Galle, Tyson Rogers, Samuel Sears, Faiez Zannad
Summary: The study aimed to assess sex differences in the efficacy and safety of baroreflex activation therapy in heart failure patients. Women had poorer baseline quality of life than men but showed similar improvements with therapy. Women had a significant improvement in NT-proBNP levels, while men did not.
JACC-HEART FAILURE
(2021)
Review
Nutrition & Dietetics
Evasio Pasini, Giovanni Corsetti, Francesco Saverio Dioguardi
Summary: Chronic heart failure (CHF) remains a major health problem in industrialized countries, despite therapeutic improvements. Malnutrition, especially protein energy malnutrition, is present in more than half of CHF patients and is an independent predictor of prognosis. Nutritional supplementation and exercise training have been used to treat this condition, but their effectiveness is inconclusive. This paper discusses the molecular mechanisms of specific nutritional supplementation and exercise training that may improve anabolic pathways, particularly focusing on the relationship between exercise and the mTOR complex subunit as Deptor and/or related signaling proteins.
Article
Veterinary Sciences
Tomislav Speranda, Valentina Pavic, Zdenko Loncaric, Marcela Speranda, Maja Popovic, Vesna Gantner, Mislav Didara
Summary: The study demonstrates that supplementing slightly higher levels of organic selenium, combined with natural zeolite, can increase selenium deposition in tissues of growing pigs, enhance antioxidant status, and strengthen the immune system.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Article
Biochemistry & Molecular Biology
Amra Jujic, John Molvin, Lutz Schomburg, Oliver Hartmann, Andreas Bergmann, Olle Melander, Martin Magnusson
Summary: A recent study found that high selenium levels are associated with reduced mortality and incidence of heart failure (HF), but only in non-smokers. This study aimed to investigate whether selenoprotein P (SELENOP) is associated with incident HF. The results showed that low SELENOP levels are associated with a higher risk of incident HF in the general population.
FREE RADICAL BIOLOGY AND MEDICINE
(2023)
Review
Biochemistry & Molecular Biology
Emilie Dubois-Deruy, Yara El Masri, Annie Turkieh, Philippe Amouyel, Florence Pinet, Jean-Sebastien Annicotte
Summary: Lysine acetylation is a conserved mechanism that affects various biological processes, and its dysregulation is associated with cardiac dysfunction. This review summarizes the regulation of cardiac acetylation and its roles in both physiological and pathological conditions, highlighting its importance in cardiovascular diseases and suggesting KATs and KDACs as potential therapeutic targets for heart failure.
Article
Cardiac & Cardiovascular Systems
Michael R. Zile, Maria Rosa R. Costanzo, Ekaterina M. Ippolito, Yan Zhang, Russell Stapleton, Ashish Sadhu, Javier Jimenez, Joe Hobbs, Vinod Sharma, Eduardo N. Warman, Lindsay Streeter, Javed Butler
Summary: The study aimed to determine the feasibility of implementing a heart failure management strategy using a device-based risk stratification model and standardized ambulatory medication intervention. The results support the testing of an ambulatory medication intervention strategy in a large randomized clinical trial based on individualized device risk stratification, physician-directed, and CHFN-implemented.
Article
Medicine, Research & Experimental
Ram Gelman, Noa Hurvitz, Rima Nesserat, Yotam Kolben, Dean Nachman, Khurram Jamil, Samuel Agus, Rabea Asleh, Offer Amir, Marc Berg, Yaron Ilan
Summary: This study utilized a second-generation artificial intelligence system to manage diuretic therapy for congestive heart failure patients. The personalized algorithm-controlled regimens significantly improved diuretic resistance, as well as various clinical indicators.
BIOMEDICINE & PHARMACOTHERAPY
(2023)
Article
Endocrinology & Metabolism
Jianing Bi, Lulu Song, Lulin Wang, Binbin Su, Mingyang Wu, Dankang Li, Shuohua Chen, Yunyun Liu, Yingping Yang, Ziyi Zhou, Yonghua Hu, Youjie Wang, Shouling Wu, Yaohua Tian
Summary: The study suggests that metabolically healthy obese (MHO) status is associated with an increased risk of heart failure (HF). Even stable MHO individuals have a higher risk of HF compared to stable metabolically healthy normal weight individuals. Maintaining metabolic health may play a crucial role in preventing HF.
DIABETES & METABOLISM
(2022)
Article
Biochemistry & Molecular Biology
Xuan Wang, Bin Yang, Hui-Li Cao, Rui-Ying Wang, Zhao-Yang Lu, Rui-Fang Chi, Bao Li
Summary: Selenium pretreatment has protective effects on LPS-induced myocardial injury by improving myocardial damage and dysfunction, reducing inflammation, oxidative stress, and myocardial apoptosis, as well as inactivating the Sting pathway.
BIOLOGICAL TRACE ELEMENT RESEARCH
(2021)
Review
Pharmacology & Pharmacy
Reza Tabrizi, Vahidreza Ostadmohammadi, Kamran B. Lankarani, Maryam Akbari, Hamideh Akbari, Sina vakili, Maryam Shokrpour, Fariba Kolandooz, Vajihe Rouhi, Zatollah Asemi
EUROPEAN JOURNAL OF PHARMACOLOGY
(2019)
Review
Biotechnology & Applied Microbiology
Reza Tabrizi, Vahidreza Ostadmohammadi, Maryam Akbari, Kamran B. Lankarani, Sina Vakili, Payam Peymani, Maryam Karamali, Fariba Kolahdooz, Zatollah Asemi
Summary: This meta-analysis research found that probiotic supplementation has positive effects on clinical symptoms, weight loss, glycemic control, lipid and hormonal profiles, as well as biomarkers of inflammation and oxidative stress in patients with polycystic ovary syndrome (PCOS).
PROBIOTICS AND ANTIMICROBIAL PROTEINS
(2022)
Correction
Peripheral Vascular Disease
Maryam Akbari, Vahidreza Ostadmohammadi, Naghmeh Mirhosseini, Kamran B. Lankarani, Reza Tabrizi, Zahra Keshtkaran, Russel J. Reiter, Zatollah Asemi
JOURNAL OF HUMAN HYPERTENSION
(2020)
Article
Nutrition & Dietetics
Vahidreza Ostadmohammadi, Alireza Soleimani, Fereshteh Bahmani, Esmat Aghadavod, Reza Ramezani, Russel J. Reiter, Mohammad Ali Mansournia, Zarrin Banikazemi, Maryam Soleimani, Marsa Zaroudi, Zatollah Asemi
JOURNAL OF RENAL NUTRITION
(2020)
Article
Biochemistry & Molecular Biology
Mohammad Karimian, Ali Momeni, Amir Farmohammadi, Mohaddeseh Behjati, Marjan Jafari, Fariba Raygan
JOURNAL OF CELLULAR BIOCHEMISTRY
(2020)
Article
Clinical Neurology
Reza Daneshvar Kakhaki, Vahidreza Ostadmohammadi, Ebrahim Kouchaki, Esmat Aghadavod, Fereshteh Bahmani, Omid Reza Tamtaji, Russel J. Reiter, Mohammad Ali Mansournia, Zatollah Asemi
CLINICAL NEUROLOGY AND NEUROSURGERY
(2020)
Article
Endocrinology & Metabolism
Vahidreza Ostadmohammadi, Fariba Raygan, Zatollah Asemi
Summary: ALA supplementation in patients with T2DM and CHD for 12 weeks showed beneficial effects on BDI, hs-CRP, TAC, MDA values, and gene expression of IL-1 and TGF-beta.
JOURNAL OF DIABETES AND METABOLIC DISORDERS
(2022)
Article
Medicine, General & Internal
Zahra Vahedpour, Homa Boroumand, Shirin Tabatabaee Anaraki, Zohre Tabasi, Hossein Motedayyen, Hossein Akbari, Fariba Raygan, Vahidreza Ostadmohammadi
Summary: The study concluded that isoflavone supplementation significantly improved endometrial histology in premenopausal women with nonatypical endometrial hyperplasia compared to the placebo group. However, there were no significant differences in serum estradiol levels and drug side effects between the two groups.
INTERNATIONAL JOURNAL OF CLINICAL PRACTICE
(2022)
Article
Food Science & Technology
Yunes Panahi, Vahidreza Ostadmohammadi, Fariba Raygan, Mohammad Reza Sharif, Amirhossein Sahebkar
Summary: The study showed that N-acetylcysteine (NAC) administration in individuals with metabolic syndrome (MetS) can positively impact glycemic homeostasis, HDL-cholesterol levels, inflammatory status, and antioxidant defense system. This suggests that NAC may be a new strategy for improving metabolic parameters in individuals with MetS.
JOURNAL OF FUNCTIONAL FOODS
(2022)
Article
Clinical Neurology
Babak Solani, Motahare Talebian Ardestani, Homa Boroumand, Vahidreza Ostadmohammadi, Mohammad Hallajnejad, Mansour Kashani Zade, Amirhossein Loghman, Ahmad Talebian Ardestani
Summary: This study found that male gender, larger head circumference, primiparity, multiple pregnancy, supine sleep position, and abnormal presentation in the uterus are associated with an increased incidence of positional plagiocephaly.
IRANIAN JOURNAL OF CHILD NEUROLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Gholamreza Namazi, Raziyeh Salami, Morteza Pourfarzam, Parastoo Asa, Alireza Ma, Fariba Raygan
Summary: The study observed significantly lower serum levels of apelin in patients with unstable CAD compared to stable CAD patients and non-CAD subjects. There was an inverse correlation between serum apelin levels and the severity of coronary stenosis in CAD patients. However, there was no significant difference in ghrelin levels among the three groups.
INDIAN HEART JOURNAL
(2021)
Article
Nutrition & Dietetics
Rana Shafabakhsh, Moein Mobini, Fariba Raygan, Esmat Aghadavod, Vahidreza Ostadmohammadi, Elaheh Amirani, Mohammad Ali Mansournia, Zatollah Asemi
CLINICAL NUTRITION ESPEN
(2020)
Review
Endocrinology & Metabolism
Reza Tabrizi, Afshin Borhani-Haghighi, Naghmeh Mirhosseini, Kamran B. Lankarani, Ahmad Naghibzadeh-Tahami, Maryam Akbari, Seyed Taghi Heydari, Mojgan Sangari, Fariba Kolahdooz, Fariba Raygan, Zatollah Asemi
JOURNAL OF DIABETES AND METABOLIC DISORDERS
(2019)