Chemerin suppresses hepatocellular carcinoma metastasis through CMKLR1-PTEN-Akt axis

Chemerin has a protective role in hepatocellular carcinoma by inhibiting the expression of IL-6 and GM-CSF and MDSC accumulation

(2017) Y Lin et al.   ONCOGENE

Curcumin inhibits the invasion of thyroid cancer cells via down-regulation of PI3K/Akt signaling pathway

(2014) XiaoBo Xu et al.   GENE

Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

(2014) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

A dual tyrosine kinase inhibitor lapatinib suppresses overexpression of matrix metallopeptidase 1 (MMP1) in endometrial cancer

(2014) Chiao-Yun Lin et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

RFP-mediated ubiquitination of PTEN modulates its effect on AKT activation

(2013) James T Lee et al.   CELL RESEARCH

Transforming growth factor-α activates pancreatic stellate cells and may be involved in matrix metalloproteinase-1 upregulation

(2013) Hiroki Tahara et al.   LABORATORY INVESTIGATION

The chemoattractant chemerin suppresses melanoma by recruiting natural killer cell antitumor defenses

(2012) Russell K. Pachynski et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Human articular chondrocytes express ChemR23 and chemerin; ChemR23 promotes inflammatory signalling upon binding the ligand chemerin21-157

(2011) Vivian Berg et al.   ARTHRITIS RESEARCH & THERAPY

Identification of chemerin receptor (ChemR23) in human endothelial cells: Chemerin-induced endothelial angiogenesis

(2010) Jaspreet Kaur et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Antitumor Effect after Radiofrequency Ablation of Murine Hepatoma Is Augmented by an Active Variant of CC Chemokine Ligand 3/Macrophage Inflammatory Protein-1 

(2010) N. Iida et al.   CANCER RESEARCH

Ubiquitination of PTEN (Phosphatase and Tensin Homolog) Inhibits Phosphatase Activity and Is Enhanced by Membrane Targeting and Hyperosmotic Stress

(2010) Helene Maccario et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rak Functions as a Tumor Suppressor by Regulating PTEN Protein Stability and Function

(2009) Eun-Kyoung Yim et al.   CANCER CELL

Retinoids regulate genes involved in retinoic acid synthesis and transport in human myometrial and fibroid smooth muscle cells

(2008) M. Zaitseva et al.   HUMAN REPRODUCTION