27-Hydroxycholesterol increases α-synuclein protein levels through proteasomal inhibition in human dopaminergic neurons
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Title
27-Hydroxycholesterol increases α-synuclein protein levels through proteasomal inhibition in human dopaminergic neurons
Authors
Keywords
27-Hydroxycholesterol, Αlpha-synuclein, Liver X receptor, Parkinson’s disease, Dopaminergic neurons, Proteasomal dysfunction
Journal
BMC NEUROSCIENCE
Volume 19, Issue 1, Pages -
Publisher
Springer Nature
Online
2018-04-04
DOI
10.1186/s12868-018-0420-5
References
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Note: Only part of the references are listed.- Hsp70 - a master regulator in protein degradation
- (2017) María Rosario Fernández-Fernández et al. FEBS LETTERS
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- (2017) Haiyang Wang et al. Experimental and Therapeutic Medicine
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- (2015) Maura Heverin et al. BEHAVIOURAL BRAIN RESEARCH
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- (2015) Wei-Wei Ma et al. NEUROCHEMICAL RESEARCH
- The Cholesterol Metabolite 27-Hydroxycholesterol Promotes Atherosclerosis via Proinflammatory Processes Mediated by Estrogen Receptor Alpha
- (2014) Michihisa Umetani et al. Cell Metabolism
- Oxidative Stress and Its Significant Roles in Neurodegenerative Diseases and Cancer
- (2014) Raynoo Thanan et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Regulated protein turnover: snapshots of the proteasome in action
- (2014) Sucharita Bhattacharyya et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Perilous journey: a tour of the ubiquitin–proteasome system
- (2014) Gary Kleiger et al. TRENDS IN CELL BIOLOGY
- The ubiquitin-proteasome system in neurodegenerative diseases: precipitating factor, yet part of the solution
- (2014) Nico P. Dantuma et al. Frontiers in Molecular Neuroscience
- Action mechanisms of Liver X Receptors
- (2013) Chiara Gabbi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Prospective Study of Statin Use and Risk of Parkinson Disease
- (2012) Xiang Gao ARCHIVES OF NEUROLOGY
- Oxysterols as biomarkers in neurodegenerative diseases
- (2011) Valerio Leoni et al. CHEMISTRY AND PHYSICS OF LIPIDS
- Ubiquitin–proteasome pathway and cellular responses to oxidative stress
- (2011) Fu Shang et al. FREE RADICAL BIOLOGY AND MEDICINE
- The oxysterol 27-hydroxycholesterol regulates α-synuclein and tyrosine hydroxylase expression levels in human neuroblastoma cells through modulation of liver X receptors and estrogen receptors-relevance to Parkinson’s disease
- (2011) Gurdeep Marwarha et al. JOURNAL OF NEUROCHEMISTRY
- Increased appearance rate of 27-hydroxycholesterol in vivo in hypercholesterolemia: A possible compensatory mechanism
- (2011) M. Bertolotti et al. NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
- Case–control study of risk of Parkinson's disease in relation to hypertension, hypercholesterolemia, and diabetes in Japan
- (2010) Yoshihiro Miyake et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- A critical evaluation of the ubiquitin–proteasome system in Parkinson's disease
- (2009) Casey Cook et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Cholesterol Oxidation Products and Disease: An Emerging Topic of Interest in Medicinal Chemistry
- (2009) Barbara Sottero et al. CURRENT MEDICINAL CHEMISTRY
- Oxysterols and neurodegenerative diseases
- (2009) Ingemar Björkhem et al. MOLECULAR ASPECTS OF MEDICINE
- Lipid-lowering drugs are associated with delayed onset and slower course of Parkinson's disease
- (2009) Eugénie Mutez et al. PHARMACOLOGICAL RESEARCH
- Interactions between Hsp70 and the Hydrophobic Core of α-Synuclein Inhibit Fibril Assembly†
- (2008) Kelvin C. Luk et al. BIOCHEMISTRY
- Differential effects of 24-hydroxycholesterol and 27-hydroxycholesterol on tyrosine hydroxylase and α-synuclein in human neuroblastoma SH-SY5Y cells
- (2008) Jaya Prasanthi Rantham Prabhakara et al. JOURNAL OF NEUROCHEMISTRY
- Total cholesterol and the risk of Parkinson disease
- (2008) G. Hu et al. NEUROLOGY
- Regulation of α-synuclein expression by liver X receptor ligands in vitro
- (2008) Danni Cheng et al. NEUROREPORT
- Dietary fats, cholesterol and iron as risk factors for Parkinson's disease
- (2008) Karen M. Powers et al. PARKINSONISM & RELATED DISORDERS
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