Modelling population-level impact to inform target product profiles for childhood malaria vaccines

Reaching everyone, everywhere with life-saving vaccines

(2017) Margaret Chan et al.   LANCET

The US President's Malaria Initiative, Plasmodium falciparum transmission and mortality: A modelling study

(2017) Peter Winskill et al.   PLOS MEDICINE

Delayed fractional dose regimen of the RTS,S/AS01 malaria vaccine candidate enhances an IgG4 response that inhibits serum opsonophagocytosis

(2017) Sidhartha Chaudhury et al.   Scientific Reports

Fractional Third and Fourth Dose of RTS,S/AS01 Malaria Candidate Vaccine: A Phase 2a Controlled Human Malaria Parasite Infection and Immunogenicity Study

(2016) Jason A. Regules et al.   JOURNAL OF INFECTIOUS DISEASES

Public health impact and cost-effectiveness of the RTS,S/AS01 malaria vaccine: a systematic comparison of predictions from four mathematical models

(2016) Melissa A Penny et al.   LANCET

Estimating the most efficient allocation of interventions to achieve reductions in Plasmodium falciparum malaria burden and transmission in Africa: a modelling study

(2016) Patrick G T Walker et al.   Lancet Global Health

Efficacy and safety of RTS,S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial

(2015)   LANCET

Immunogenicity of the RTS,S/AS01 malaria vaccine and implications for duration of vaccine efficacy: secondary analysis of data from a phase 3 randomised controlled trial

(2015) Michael T White et al.   LANCET INFECTIOUS DISEASES

Gradual acquisition of immunity to severe malaria with increasing exposure

(2015) J. T. Griffin et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Estimates of the changing age-burden of Plasmodium falciparum malaria disease in sub-Saharan Africa

(2014) Jamie T. Griffin et al.   Nature Communications

Implications of the licensure of a partially efficacious malaria vaccine on evaluating second-generation vaccines

(2013) Freya JI Fowkes et al.   BMC Medicine

Safety and efficacy of the RTS,S/AS01 E candidate malaria vaccine given with expanded-programme-on-immunisation vaccines: 19 month follow-up of a randomised, open-label, phase 2 trial

(2011) Kwaku Poku Asante et al.   LANCET INFECTIOUS DISEASES

A Research Agenda for Malaria Eradication: Modeling

(2011)   PLOS MEDICINE

Reducing Plasmodium falciparum Malaria Transmission in Africa: A Model-Based Evaluation of Intervention Strategies

(2010) Jamie T. Griffin et al.   PLOS MEDICINE

The development of the RTS,S malaria vaccine candidate: challenges and lessons

(2009) W. R. BALLOU   PARASITE IMMUNOLOGY

Loss of Population Levels of Immunity to Malaria as a Result of Exposure-Reducing Interventions: Consequences for Interpretation of Disease Trends

(2009) Azra C. Ghani et al.   PLoS One

Vaccination greatly reduces disease, disability, death and inequity worldwide

(2008) FE Andre et al.   BULLETIN OF THE WORLD HEALTH ORGANIZATION