Characterization of the human RFX transcription factor family by regulatory and target gene analysis

Genes and molecular pathways underpinning ciliopathies

(2017) Jeremy F. Reiter et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Genetic regulatory signatures underlying islet gene expression and type 2 diabetes

(2017) Arushi Varshney et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rfx2 Stabilizes Foxj1 Binding at Chromatin Loops to Enable Multiciliated Cell Gene Expression

(2017) Ian K. Quigley et al.   PLoS Genetics

Conditional knockout mice demonstrate function of Klf5 as a myeloid transcription factor

(2016) Nur Hezrin Shahrin et al.   BLOOD

Molecular Diversity of Midbrain Development in Mouse, Human, and Stem Cells

(2016) Gioele La Manno et al.   CELL

Membrane-Localized Estrogen Receptor 1 Is Required for Normal Male Reproductive Development and Function in Mice

(2016) Manjunatha K. Nanjappa et al.   ENDOCRINOLOGY

Ciliary dyslexia candidate genes DYX1C1 and DCDC2 are regulated by Regulatory Factor X (RFX) transcription factors through X-box promoter motifs

(2016) Kristiina Tammimies et al.   FASEB JOURNAL

High-throughput functional comparison of promoter and enhancer activities

(2016) Thomas A. Nguyen et al.   GENOME RESEARCH

Novel Roles and Mechanism for Krüppel-like Factor 16 (KLF16) Regulation of Neurite Outgrowth and Ephrin Receptor A5 (EphA5) Expression in Retinal Ganglion Cells

(2016) Jianbo Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RFX1 maintains testis cord integrity by regulating the expression ofItga6in male mouse embryos

(2016) Bo Wang et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Transcription Factor RFX2 Is a Key Regulator of Mouse Spermiogenesis

(2016) Yujian Wu et al.   Scientific Reports

Estrogen receptor signaling during vertebrate development

(2015) Maria Bondesson et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

IBS: an illustrator for the presentation and visualization of biological sequences: Fig. 1.

(2015) Wenzhong Liu et al.   BIOINFORMATICS

Sox21 regulates the progression of neuronal differentiation in a dose-dependent manner

(2015) Niteace Whittington et al.   DEVELOPMENTAL BIOLOGY

The ciliogenic transcription factor Rfx3 is required for the formation of the thalamocortical tract by regulating the patterning of prethalamus and ventral telencephalon

(2015) Dario Magnani et al.   HUMAN MOLECULAR GENETICS

Role and Regulation of Myeloid Zinc Finger Protein 1 in Cancer

(2015) Taka Eguchi et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The transcription factor ATF7 mediates lipopolysaccharide-induced epigenetic changes in macrophages involved in innate immunological memory

(2015) Keisuke Yoshida et al.   NATURE IMMUNOLOGY

A new transcription factor for mitosis: inSchizosaccharomyces pombe, the RFX transcription factor Sak1 works with forkhead factors to regulate mitotic expression

(2015) Angad Garg et al.   NUCLEIC ACIDS RESEARCH

JASPAR 2016: a major expansion and update of the open-access database of transcription factor binding profiles

(2015) Anthony Mathelier et al.   NUCLEIC ACIDS RESEARCH

RFX transcription factors are essential for hearing in mice

(2015) Ran Elkon et al.   Nature Communications

Gateways to the FANTOM5 promoter level mammalian expression atlas

(2015) Marina Lizio et al.   GENOME BIOLOGY

Sp1/Sp3 transcription factors regulate hallmarks of megakaryocyte maturation and platelet formation and function

(2014) M. Meinders et al.   BLOOD

Switching on cilia: transcriptional networks regulating ciliogenesis

(2014) S. P. Choksi et al.   DEVELOPMENT

Insulin secretion from beta cells in intact mouse islets is targeted towards the vasculature

(2014) Jiun T. Low et al.   DIABETOLOGIA

Multicilin drives centriole biogenesis via E2f proteins

(2014) L. Ma et al.   GENES & DEVELOPMENT

An atlas of active enhancers across human cell types and tissues

(2014) Robin Andersson et al.   NATURE

Evolutionarily Dynamic Alternative Splicing of GPR56 Regulates Regional Cerebral Cortical Patterning

(2014) B.-I. Bae et al.   SCIENCE

RFX6 Regulates Insulin Secretion by Modulating Ca2+ Homeostasis in Human β Cells

(2014) Vikash Chandra et al.   Cell Reports

Rfx6 Maintains the Functional Identity of Adult Pancreatic β Cells

(2014) Julie Piccand et al.   Cell Reports

DNA-Binding Specificities of Human Transcription Factors

(2013) Arttu Jolma et al.   CELL

Neural development is dependent on the function of specificity protein 2 in cell cycle progression

(2013) H. Liang et al.   DEVELOPMENT

SP8 regulates signaling centers during craniofacial development

(2013) Abigail D. Kasberg et al.   DEVELOPMENTAL BIOLOGY

Expression of the transcription factor regulatory factor X1 in the mouse brain

(2013) Chenzhuo Feng et al.   FOLIA HISTOCHEMICA ET CYTOBIOLOGICA

A Sympathetic Neuron Autonomous Role for Egr3-Mediated Gene Regulation in Dendrite Morphogenesis and Target Tissue Innervation

(2013) D. H. Quach et al.   JOURNAL OF NEUROSCIENCE

Transcription Factor TFAP2C Regulates Major Programs Required for Murine Fetal Germ Cell Maintenance and Haploinsufficiency Predisposes to Teratomas in Male Mice

(2013) Jana Schemmer et al.   PLoS One

RFX3 Modulation of FOXJ1 regulation of cilia genes in the human airway epithelium

(2013) Lukas Didon et al.   RESPIRATORY RESEARCH

The mouse transcription factor-like 5 gene encodes a protein localized in the manchette and centriole of the elongating spermatid

(2013) Y. Shi et al.   Andrology

The in vivo dissection of direct RFX-target gene promoters in C. elegans reveals a novel cis-regulatory element, the C-box

(2012) Jan Burghoorn et al.   DEVELOPMENTAL BIOLOGY

The Transcription Factors Egr2 and Egr3 Are Essential for the Control of Inflammation and Antigen-Induced Proliferation of B and T Cells

(2012) Suling Li et al.   IMMUNITY

FIMO: scanning for occurrences of a given motif

(2011) Charles E. Grant et al.   BIOINFORMATICS

RFX2 is broadly required for ciliogenesis during vertebrate development

(2011) Mei-I Chung et al.   DEVELOPMENTAL BIOLOGY

The Gene Regulatory Cascade Linking Proneural Specification with Differentiation in Drosophila Sensory Neurons

(2011) Sebastián Cachero et al.   PLOS BIOLOGY

Transcriptional control of genes involved in ciliogenesis: a first step in making cilia

(2010) Joëlle Thomas et al.   BIOLOGY OF THE CELL

Convergent evolution of RFX transcription factors and ciliary genes predated the origin of metazoans

(2010) Jeffrey SC Chu et al.   BMC EVOLUTIONARY BIOLOGY

Transcriptional regulation of the Alström syndrome gene ALMS1 by members of the RFX family and Sp1

(2010) Tracey L. Purvis et al.   GENE

Rfx6 directs islet formation and insulin production in mice and humans

(2010) Stuart B. Smith et al.   NATURE

Regulatory Factor X (RFX)-mediated transcriptional rewiring of ciliary genes in animals

(2010) B. P. Piasecki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Knockout of the regulatory factor X1 gene leads to early embryonic lethality

(2009) Chenzhuo Feng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Rfx6 is an Ngn3-dependent winged helix transcription factor required for pancreatic islet cell development

(2009) Josselin Soyer et al.   DEVELOPMENT

Differential expression of Rfx1-4 during mouse spermatogenesis

(2009) W. Stephen Kistler et al.   GENE EXPRESSION PATTERNS

Worms With a Single Functional Sensory Cilium Generate Proper Neuron-Specific Behavioral Output

(2009) G. Senti et al.   GENETICS

RFX3 governs growth and beating efficiency of motile cilia in mouse and controls the expression of genes involved in human ciliopathies

(2009) L. El Zein et al.   JOURNAL OF CELL SCIENCE

Identification and characterization of novel human tissue-specific RFX transcription factors

(2008) Syed Aftab et al.   BMC EVOLUTIONARY BIOLOGY

Distinct Isoforms of the RFX Transcription Factor DAF-19 Regulate Ciliogenesis and Maintenance of Synaptic Activity

(2008) Gabriele Senti et al.   MOLECULAR BIOLOGY OF THE CELL

Distinct functions of Egr gene family members in cognitive processes

(2008) Roseline Poirier   Frontiers in Neuroscience