Interferon regulatory factor 1 inactivation in human cancer

IRF1 up-regulates isg15 gene expression in dsRNA stimulation or CSFV infection by targeting nucleotides −487 to −325 in the 5′ flanking region

(2018) Xiao-Quan Li et al.   MOLECULAR IMMUNOLOGY

Generation and characterization of a conditional allele of Interferon Regulatory Factor 6

(2017) Arianna L. Smith et al.   GENESIS

Interferon Regulatory Factor 6 Is Necessary for Salivary Glands and Pancreas Development

(2017) K.A. Metwalli et al.   JOURNAL OF DENTAL RESEARCH

Interferon regulatory factor 5 in human autoimmunity and murine models of autoimmune disease

(2016) Hayley L. Eames et al.   Translational Research

Specific detection of interferon regulatory factor 5 (IRF5): A case of antibody inequality

(2016) Dan Li et al.   Scientific Reports

Irf5 deficiency in macrophages promotes beneficial adipose tissue expansion and insulin sensitivity during obesity

(2015) Elise Dalmas et al.   NATURE MEDICINE

Adoptive cell transfer as personalized immunotherapy for human cancer

(2015) S. A. Rosenberg et al.   SCIENCE

Interferon-regulatory factor-1 (IRF1) regulates bevacizumab induced autophagy

(2015) Ji Liang et al.   Oncotarget

Interferon regulatory factor 6 regulates keratinocyte migration

(2014) L. C. Biggs et al.   JOURNAL OF CELL SCIENCE

The Roles of Interferon Regulatory Factors 1 and 2 in the Progression of Human Pancreatic Cancer

(2014) Toshitaka Sakai et al.   PANCREAS

Identification of IRF1 as critical dual regulator of Smac mimetic-induced apoptosis and inflammatory cytokine response

(2014) I Eckhardt et al.   Cell Death & Disease

Transcription factor IRF5 drives P2X4R+-reactive microglia gating neuropathic pain

(2014) Takahiro Masuda et al.   Nature Communications

IRF-1 responsiveness to IFN-γ predicts different cancer immune phenotypes

(2013) D Murtas et al.   BRITISH JOURNAL OF CANCER

miR-23a Targets Interferon Regulatory Factor 1 and Modulates Cellular Proliferation and Paclitaxel-Induced Apoptosis in Gastric Adenocarcinoma Cells

(2013) Xue Liu et al.   PLoS One

Interferon Regulatory Factor (IRF)-1 and IRF-2 are Associated with Prognosis and Tumor Invasion in HCC

(2012) Yong Yi et al.   ANNALS OF SURGICAL ONCOLOGY

High-throughput sequencing analysis of the chromosome 7q32 deletion reveals IRF5 as a potential tumour suppressor in splenic marginal-zone lymphoma

(2012) Vicente Fresquet et al.   BRITISH JOURNAL OF HAEMATOLOGY

Anti-tumorigenic effects of Type 1 interferon are subdued by integrated stress responses

(2012) S Bhattacharya et al.   ONCOGENE

IRF1 and NF-kB Restore MHC Class I-Restricted Tumor Antigen Processing and Presentation to Cytotoxic T Cells in Aggressive Neuroblastoma

(2012) Silvia Lorenzi et al.   PLoS One

Function and mechanism by which interferon regulatory factor-1 inhibits oncogenesis

(2012) FEI-FEI CHEN et al.   Oncology Letters

The IRF family of transcription factors

(2012) Hideyuki Yanai et al.   OncoImmunology

Interferon Regulatory Factor 1 (IRF-1) induces p21WAF1/CIP1 dependent cell cycle arrest and p21WAF1/CIP1 independent modulation of survivin in cancer cells

(2011) Michaele J. Armstrong et al.   CANCER LETTERS

Type I interferon is selectively required by dendritic cells for immune rejection of tumors

(2011) Mark S. Diamond et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IRF-2 is over-expressed in pancreatic cancer and promotes the growth of pancreatic cancer cells

(2011) Lei Cui et al.   TUMOR BIOLOGY

IFN  Restores Breast Cancer Sensitivity to Fulvestrant by Regulating STAT1, IFN Regulatory Factor 1, NF- B, BCL2 Family Members, and Signaling to Caspase-Dependent Apoptosis

(2010) Y. Ning et al.   MOLECULAR CANCER THERAPEUTICS

Interferon regulatory factor (IRF)-2 activates the HPV-16 E6–E7 promoter in keratinocytes

(2010) Michael J. Lace et al.   VIROLOGY

SUMOylated IRF-1 shows oncogenic potential by mimicking IRF-2

(2009) Sun-Mi Park et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Frequent loss of heterozygosity at the interferon regulatory factor-1 gene locus in breast cancer

(2009) Luciane R. Cavalli et al.   BREAST CANCER RESEARCH AND TREATMENT

IRF-1 transcriptionally upregulates PUMA, which mediates the mitochondrial apoptotic pathway in IRF-1-induced apoptosis in cancer cells

(2009) J Gao et al.   CELL DEATH AND DIFFERENTIATION

Role of Double-Stranded RNA Pattern Recognition Receptors in Rhinovirus-Induced Airway Epithelial Cell Responses

(2009) Q. Wang et al.   JOURNAL OF IMMUNOLOGY

GAGE, an Antiapoptotic Protein Binds and Modulates the Expression of Nucleophosmin/B23 and Interferon Regulatory Factor 1

(2009) Rupinder K. Kular et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

A ChIP–chip approach reveals a novel role for transcription factor IRF1 in the DNA damage response

(2009) Mattia Frontini et al.   NUCLEIC ACIDS RESEARCH

Role of Mdm2 acid domain interactions in recognition and ubiquitination of the transcription factor IRF-2

(2008) Susanne Pettersson et al.   BIOCHEMICAL JOURNAL

The E6E7 oncoproteins of cutaneous human papillomavirus type 38 interfere with the interferon pathway

(2008) Pablo Cordano et al.   VIROLOGY