Biosynthesis and applications of prenylquinones

A Journey across Genomes Uncovers the Origin of Ubiquinone in Cyanobacteria

(2017) Mauro Degli Esposti   Genome Biology and Evolution

The UbiK protein is an accessory factor necessary for bacterial ubiquinone (UQ) biosynthesis and forms a complex with the UQ biogenesis factor UbiJ

(2017) Laurent Loiseau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cellular factories for coenzyme Q10 production

(2017) Sean Qiu En Lee et al.   Microbial Cell Factories

Phylloquinone (Vitamin K1): Occurrence, Biosynthesis and Functions

(2017) Gilles J. Basset et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Unknown

(2017)   MOLECULAR MICROBIOLOGY

The Phytol Phosphorylation Pathway Is Essential for the Biosynthesis of Phylloquinone, which Is Required for Photosystem I Stability in Arabidopsis

(2017) Lei Wang et al.   Molecular Plant

Biochemistry of Mitochondrial Coenzyme Q Biosynthesis

(2017) Jonathan A. Stefely et al.   TRENDS IN BIOCHEMICAL SCIENCES

Conserved Function of Fibrillin5 in the Plastoquinone-9 Biosynthetic Pathway in Arabidopsis and Rice

(2017) Eun-Ha Kim et al.   Frontiers in Plant Science

The Role of Sulfide Oxidation Impairment in the Pathogenesis of Primary CoQ Deficiency

(2017) Catarina M. Quinzii et al.   Frontiers in Physiology

Novel long-chain compounds with both immunomodulatory and MenA inhibitory activities against Staphylococcus aureus and its biofilm

(2017) Seoung-ryoung Choi et al.   Scientific Reports

Cloning and characterization of decaprenyl diphosphate synthase from three different fungi

(2016) Daisuke Moriyama et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

The Methylerythritol Phosphate Pathway to Isoprenoids

(2016) Annika Frank et al.   CHEMICAL REVIEWS

Unknown

(2016)   ChemMedChem

Genomic Analysis of the Human Gut Microbiome Suggests Novel Enzymes Involved in Quinone Biosynthesis

(2016) Dmitry A. Ravcheev et al.   Frontiers in Microbiology

Plastoquinone and Ubiquinone in Plants: Biosynthesis, Physiological Function and Metabolic Engineering

(2016) Miaomiao Liu et al.   Frontiers in Plant Science

Biosynthesis and Regulation of Sulfomenaquinone, a Metabolite Associated with Virulence in Mycobacterium tuberculosis

(2016) Kimberly M. Sogi et al.   ACS Infectious Diseases

A Methyl 4-Oxo-4-phenylbut-2-enoate with in Vivo Activity against MRSA That Inhibits MenB in the Bacterial Menaquinone Biosynthesis Pathway

(2016) Joe S. Matarlo et al.   ACS Infectious Diseases

Unknown

(2016)   BIOFACTORS

Unknown

(2016)   PLANT JOURNAL

Structural and biochemical studies reveal UbiG/Coq3 as a class of novel membrane-binding proteins

(2015) Yuwei Zhu et al.   BIOCHEMICAL JOURNAL

Mechanism of MenE Inhibition by Acyl-Adenylate Analogues and Discovery of Novel Antibacterial Agents

(2015) Joe S. Matarlo et al.   BIOCHEMISTRY

Yeast Coq9 controls deamination of coenzyme Q intermediates that derive from para-aminobenzoic acid

(2015) Cuiwen H. He et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Biosynthesis of coenzyme Q in eukaryotes

(2015) Makoto Kawamukai   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Coq6 Is Responsible for the C4-deamination Reaction in Coenzyme Q Biosynthesis inSaccharomyces cerevisiae

(2015) Mohammad Ozeir et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of Coq11, a New Coenzyme Q Biosynthetic Protein in the CoQ-Synthome inSaccharomyces cerevisiae

(2015) Christopher M. Allan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

UbiX is a flavin prenyltransferase required for bacterial ubiquinone biosynthesis

(2015) Mark D. White et al.   NATURE

Unknown

(2015)   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Partial Saturation of Menaquinone in Mycobacterium tuberculosis: Function and Essentiality of a Novel Reductase, MenJ

(2015) Ashutosh Upadhyay et al.   ACS Central Science

Plant tolerance to excess light energy and photooxidative damage relies on plastoquinone biosynthesis

(2015) Brigitte Ksas et al.   Scientific Reports

Identification of the Binding Site of the Quinone-Head Group in Mitochondrial Coq10 by Photoaffinity Labeling

(2014) Masatoshi Murai et al.   BIOCHEMISTRY

Lysocin E is a new antibiotic that targets menaquinone in the bacterial membrane

(2014) Hiroshi Hamamoto et al.   Nature Chemical Biology

Functional Conservation of Coenzyme Q Biosynthetic Genes among Yeasts, Plants, and Humans

(2014) Kazuhiro Hayashi et al.   PLoS One

Loss of quaternary structure is associated with rapid sequence divergence in the OSBS family

(2014) D. Odokonyero et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional convergence of structurally distinct thioesterases from cyanobacteria and plants involved in phylloquinone biosynthesis

(2013) Fabienne Furt et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Methylerythritol Phosphate Pathway of Isoprenoid Biosynthesis

(2013) Lishan Zhao et al.   Annual Review of Biochemistry

Network Analysis of the MVA and MEP Pathways for Isoprenoid Synthesis

(2013) Eva Vranová et al.   Annual Review of Plant Biology

Deamination of 6-Aminodeoxyfutalosine in Menaquinone Biosynthesis by Distantly Related Enzymes

(2013) Alissa M. Goble et al.   BIOCHEMISTRY

Cloning and polymorphism analysis of the 2-methyl-6-phytyl-1,4-benzoquinol methyltransferase gene (VTE3) in Arachis hypogaea, A. duranensis, and A. ipaënsis

(2013) F.Z. Liu et al.   GENETICS AND MOLECULAR RESEARCH

Identification of a Hotdog Fold Thioesterase Involved in the Biosynthesis of Menaquinone in Escherichia coli

(2013) M. Chen et al.   JOURNAL OF BACTERIOLOGY

Chorismate Pyruvate-Lyase and 4-Hydroxy-3-solanesylbenzoate Decarboxylase Are Required for Plastoquinone Biosynthesis in the CyanobacteriumSynechocystissp. PCC6803

(2013) Christian Pfaff et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ubiI,a New Gene inEscherichia coliCoenzyme Q Biosynthesis, Is Involved in Aerobic C5-hydroxylation

(2013) Mahmoud Hajj Chehade et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structures of E. coli Native MenH and Two Active Site Mutants

(2013) Jodie M. Johnston et al.   PLoS One

Structural enzymology ofHelicobacter pylorimethylthioadenosine nucleosidase in the futalosine pathway

(2013) Robbert Q. Kim et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Molecular genetics of ubiquinone biosynthesis in animals

(2012) Ying Wang et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Mechanism of the Intramolecular Claisen Condensation Reaction Catalyzed by MenB, a Crotonase Superfamily Member

(2011) Huei-Jiun Li et al.   BIOCHEMISTRY

Coenzyme Q Biosynthesis: Coq6 Is Required for the C5-Hydroxylation Reaction and Substrate Analogs Rescue Coq6 Deficiency

(2011) Mohammad Ozeir et al.   CHEMISTRY & BIOLOGY

Identification of a New Gene Required for the Biosynthesis of Rhodoquinone in Rhodospirillum rubrum

(2011) Z. T. Lonjers et al.   JOURNAL OF BACTERIOLOGY

Involvement of thermoplasmaquinone-7 in transplasma membrane electron transport of Entamoeba histolytica trophozoites: a key molecule for future rational chemotherapeutic drug designing

(2011) Nilay Nandi et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Calcium Binding and Transport by Coenzyme Q

(2011) Ivan Bogeski et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Diversity of the Early Step of the Futalosine Pathway

(2010) Chisato Arakawa et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Enzymes of the mevalonate pathway of isoprenoid biosynthesis

(2010) Henry M. Miziorko   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Occurrence, biosynthesis and function of isoprenoid quinones

(2010) Beatrycze Nowicka et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

A Drosophila model for primary coenzyme Q deficiency and dietary rescue in the developing nervous system

(2010) J. Grant et al.   Disease Models & Mechanisms

A subunit of decaprenyl diphosphate synthase stabilizes octaprenyl diphosphate synthase inEscherichia coliby forming a high-molecular weight complex

(2010) Tie-Zhong Cui et al.   FEBS LETTERS

Catalytic Reactions of the Homogentisate Prenyl Transferase Involved in Plastoquinone-9 Biosynthesis

(2010) Radin Sadre et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of UBIAD1 as a novel human menaquinone-4 biosynthetic enzyme

(2010) Kimie Nakagawa et al.   NATURE

A historical perspective on the discovery of statins

(2010) Akira ENDO   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

Structural and functional analysis of Vitamin K2 synthesis protein MenD

(2009) Amit Priyadarshi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Biosynthesis and bioproduction of coenzyme Q10by yeasts and other organisms

(2009) Makoto Kawamukai   BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

Rhodoplanes serenus sp. nov., a purple non-sulfur bacterium isolated from pond water

(2009) K. Okamura et al.   INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY

PAD1 and FDC1 are essential for the decarboxylation of phenylacrylic acids in Saccharomyces cerevisiae

(2009) Nobuhiko Mukai et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Crystal structure of MqnD (TTHA1568), a menaquinone biosynthetic enzyme from Thermus thermophilus HB8

(2009) Ryoichi Arai et al.   JOURNAL OF STRUCTURAL BIOLOGY

The effect of different ubiquinones on lifespan in Caenorhabditis elegans

(2009) Yu-Ying Yang et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Clinical aspects of coenzyme Q10: An update

(2009) Gian Paolo Littarru et al.   NUTRITION

Heteromer formation of a long-chain prenyl diphosphate synthase from fission yeast Dps1 and budding yeast Coq1*

(2008) Mei Zhang et al.   FEBS Journal

Coq10, a mitochondrial coenzyme Q binding protein, is required for proper respiration in Schizosaccharomyces pombe

(2008) Tie-Zhong Cui et al.   FEBS Journal

Comparison of a coq7 deletion mutant with other respiration-defective mutants in fission yeast

(2008) Risa Miki et al.   FEBS Journal

Saposin B Is a Human Coenzyme Q10-Binding/Transfer Protein

(2008) GuangZhi Jin et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

The AAE14 gene encodes the Arabidopsis o-succinylbenzoyl-CoA ligase that is essential for phylloquinone synthesis and photosystem-I function

(2008) Hyun Uk Kim et al.   PLANT JOURNAL

An Alternative Menaquinone Biosynthetic Pathway Operating in Microorganisms

(2008) T. Hiratsuka et al.   SCIENCE

Participation of chlorobiumquinone in the transplasma membrane electron transport system of Leishmania donovani promastigote: Effect of near-ultraviolet light on the redox reaction of plasma membrane

(2007) Shibendu Biswas et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS