Article
Reproductive Biology
Luisa Ramirez-Agamez, Camilo Hernandez-Aviles, Dickson D. Varner, Charles C. Love
Summary: This study explores stallion-associated factors in intracytoplasmic sperm injection (ICSI) using frozen/thawed sperm. The results indicate that the composition of freezing extender affects the developmental competence of sperm and in vitro-matured equine oocytes after ICSI. Furthermore, there were no significant differences observed when using ejaculated or epididymal sperm, or sperm with different morphological features in ICSI outcomes.
Article
Endocrinology & Metabolism
Zhiqi Liao, Lei Cai, Chang Liu, Jie Li, Xinyao Hu, Youhua Lai, Lin Shen, Cong Sui, Hanwang Zhang, Kun Qian
Summary: A predictive nomogram model was constructed based on 11513 IVF/ICSI singleton live births, identifying 14 risk factors associated with preterm delivery. The model exhibited good performance and calibration, suggesting its potential clinical value.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Review
Genetics & Heredity
Li Fu, Shaowei Chen, Mingyong Wang, Guiying Huang, Fang Wang, Yunzhu Lan, Shuang Liu, Xia Jiang
Summary: The present study reveals the importance of conjoined oocytes in the clinical IVF setting. A successful live birth from a conjoined oocyte demonstrates that degenerated immature oocytes have no adverse effect on subsequent embryo development and pregnancy outcome. Furthermore, a literature review evaluates the origin, incidence, safety, and significance of conjoined oocytes in reproductive health.
JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
(2022)
Article
Endocrinology & Metabolism
Yuqing Jiang, Zhaoyang Shen, Jianmin Xu, Jing Zhu, Huan Wang, Wenhui Chen, Yingpu Sun, Qingling Yang
Summary: High sperm DNA fragmentation index (DFI) in overweight/obese women during ICSI cycles leads to decreased fertilization, cleavage, and high-quality embryo rates. The diminished capacity of oocytes to repair sperm DNA damage may be the cause of the decreased early developmental potential in embryos from overweight/obese patients.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Obstetrics & Gynecology
Baris Ata, Alberto Linan, Erkan Kalafat, Francisco Ruiz, Laura Melado, Asina Bayram, Ibrahim Elkhatib, Barbara Lawrenz, Human M. Fatemi
Summary: The endometrial thickness does not independently affect the live birth rate after embryo transfer. Cancelling embryo transfers with an endometrial thickness less than 7 mm may not be justified.
FERTILITY AND STERILITY
(2023)
Article
Medicine, General & Internal
Liang Chen, Hanjing Zhou, Xueli Liu, Jing Zhao, Qianrong Qi, Qingzhen Xie
Summary: This study analyzed early rescue intracytoplasmic sperm injection (r-ICSI) cycles in normal and hyper-ovarian response women and compared their cycle characteristics, pregnancy, and neonatal outcomes. The results showed that partial r-ICSI cycles had different characteristics compared to total r-ICSI cycles, and early r-ICSI delayed blastocyst development. In fresh cleavage-stage embryo transfer cycles, there was no significant difference in pregnancy and live birth rates among the groups, but reduced pregnancy outcomes were observed in fresh blastocyst transfer cycles. Early r-ICSI did not have a negative impact on preterm birth, Cesarean section, neonatal birth weight, and sex ratio.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Multidisciplinary Sciences
Wen-Jing Jiang, Zhen-Gao Sun, Jing-Yan Song
Summary: Premature initiation of progesterone luteal phase support (LPS) 24 hours after hCG trigger did not affect live birth rate in modified natural cycle frozen-thawed embryo transfer. This study provides valuable insights for clinical decisions and patient choices.
Article
Obstetrics & Gynecology
Huy H Pham, Trinh M Vu, Chau H Nguyen, Anh H Le, Dung P Nguyen, Toan D Pham, Tuong M Ho, Lan N Vuong
Summary: This study evaluated the impact of post-warming culture time on the live birth rate in day-3 and day-5 frozen embryo transfer cycles. The results showed that post-warming culture time did not significantly affect the live birth rate. Therefore, IVF centers can consider adjusting workflows based on individual patient needs.
REPRODUCTIVE MEDICINE AND BIOLOGY
(2022)
Article
Endocrinology & Metabolism
Xiaokun Hu, Yuliang Liu, Xiubing Zhang, Pingyin Lee, Yangxing Wen, Chenhui Ding, Canquan Zhou, Yanwen Xu
Summary: This study aimed to investigate the impact of oocyte degeneration after ICSI on cumulative live birth rate in young women; The results showed that oocyte degeneration is not an indicator for predicting the cumulative live birth rate.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Obstetrics & Gynecology
Edwin-Amalraj Raja, Siladitya Bhattacharya, Abha Maheshwari, David J. McLernon
Summary: This population-based retrospective cohort study compares the perinatal outcomes between frozen and fresh embryo transfer (ET) in singletons, sets of twins, and siblings. The study found that frozen ET is associated with a lower risk of preterm birth, low birthweight, and congenital anomalies in singletons and twins. However, there is a higher risk of high birthweight and being large for gestational age. Singletons conceived following frozen ET have a lower risk of low birthweight and being small for gestational age compared to a singleton sibling born after fresh ET. Overall, frozen ET appears to have both advantages and disadvantages in perinatal outcomes.
FERTILITY AND STERILITY
(2022)
Article
Obstetrics & Gynecology
Anna-Karina Aaris Henningsen, Signe Opdahl, Ulla-Britt Wennerholm, Aila Tiitinen, Steen Rasmussen, Liv Bente Romundstad, Christina Bergh, Mika Gissler, Julie Lyng Forman, Anja Pinborg
Summary: This study investigated the risk of major congenital malformations in live-born singletons conceived with intracytoplasmic sperm injection (ICSI) compared to in vitro fertilization (IVF). The findings showed that the risk of major malformations was slightly higher in live-born singletons conceived with fresh ICSI compared to fresh IVF. Children conceived through ICSI also had a higher risk of respiratory and chromosomal malformations, but the number of cases was small in each group. The risk of hypospadias was higher when ICSI was performed solely due to male factor infertility. These findings should be considered when choosing assisted reproductive technology methods for couples without male factor infertility.
FERTILITY AND STERILITY
(2023)
Article
Endocrinology & Metabolism
Kenji Ezoe, Tetsuya Miki, Tadashi Okimura, Kazuo Uchiyama, Akiko Yabuuchi, Tamotsu Kobayashi, Keiichi Kato
Summary: The absence or prolongation of the cytoplasmic halo was negatively correlated with the live birth rate after fresh cleaved embryo transfer. The characteristics of the cytoplasmic halo were strongly associated with oocyte diameter, male age, and the initial position of the male pronucleus. These findings indicate that the characteristics of the cytoplasmic halo can be used to select more competent embryos for transfer at the cleavage stage.
REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY
(2021)
Review
Reproductive Biology
Ping Pan, Lingyan Zheng, Xiaoli Chen, Jia Huang, Dongzi Yang, Yu Li
Summary: This case study describes a successful twin pregnancy achieved in a 29-year-old Chinese woman with PORD through IVF and frozen embryo transfer, providing new insights for infertility treatment in PORD women.
JOURNAL OF OVARIAN RESEARCH
(2021)
Article
Endocrinology & Metabolism
Yu Lan, Haiyan Zheng, Xin Fu, Tianwen Peng, Chen Liao, Jianan Liu, Min Liu, Geng An
Summary: Micro-TESE combined with ICSI-IVF can achieve favorable clinical outcomes for NOA patients. AZFc microdeletions are an important cause of poor embryological and clinical outcomes in NOA patients.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Obstetrics & Gynecology
Reeva Makhijani, Prachi Godiwala, James Grady, Alicia Christy, Kim Thornton, Daniel Grow, Lawrence Engmann
Summary: This retrospective cohort study aimed to evaluate if racial/ethnic differences persist in pregnancy outcomes in frozen-thawed embryo transfer (FET) cycles. The results showed that Black women had a significantly lower live birth rate and implantation rate, as well as higher clinical loss rate compared to other racial/ethnic groups.
FERTILITY AND STERILITY
(2022)