Article
Obstetrics & Gynecology
Christos A. Venetis
Summary: Embryo cryopreservation is an important part of ART, and the freeze-all strategy has shown higher live birth rates in high responders. However, there is no significant difference in normal responders. The freeze-all policy reduces the risk of ovarian hyperstimulation syndrome, but both strategies have their own risks and there is no clear safer approach.
HUMAN REPRODUCTION
(2022)
Article
Endocrinology & Metabolism
Xuelan Li, Pingping Guo, Christophe Blockeel, Xinning Li, Ling Deng, Jie Yang, Chujun Li, Min Lin, Haocun Wu, Guifeng Cai, Yunzhao Hu, Xin Chen
Summary: This study aimed to investigate the effect of storage duration of vitrified warmed embryos on pregnancy and neonatal outcomes. The results showed that within a storage period of up to 7 years, there was no impact on the pregnancy and neonatal outcomes of embryos after vitrification.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Obstetrics & Gynecology
K. M. Wong, M. van Wely, H. R. Verhoeve, E. M. Kaaijk, F. Mol, F. van der Veen, S. Repping, S. Mastenbroek
Summary: A study in the Netherlands compared the freeze-all strategy with the conventional strategy in IVF treatments, and found that the conventional strategy had a higher cumulative ongoing pregnancy rate per woman. However, further research is needed to determine the efficacy of the freeze-all strategy in different patient subgroups and embryonic development stages, and to weigh the potential benefits and risks for mothers and children.
HUMAN REPRODUCTION
(2021)
Article
Endocrinology & Metabolism
Xudong Zhang, Shanshan Wu, Guimin Hao, Xueqing Wu, Haiqin Ren, Yinfeng Zhang, Aimin Yang, Xingyu Bi, Lina Bai, Yunshan Zhang, Jichun Tan
Summary: This study found that the longer the storage time of vitrified embryos, the lower the possibility of pregnancy and live birth, but it did not affect the risk of ectopic pregnancy and miscarriage. Stratification analyses showed that the inverse correlation was significant in subpopulations with characteristics such as being under 40 years old, retrieving more than 3 oocytes, and transferring only high-quality blastocysts.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Medicine, General & Internal
Wenjing Zhou, Zhaojun Cheng, Chong Wang, Ying Feng
Summary: Sequential transplantation is a new mode of in vitro fertilization and embryo transfer. This study compared the clinical outcomes of sequential transplantation, embryo transplantation, and blastocyst transplantation in freeze-thaw embryo transfer cycles. The results showed that the sequential transplantation group had a significantly higher number of transplanted embryos than the other two groups, and the blastocyst transplantation group had the highest implantation rate. The sequential transplantation cycle can achieve a higher clinical pregnancy rate and minimize wastage of transplanted embryos, making it a viable choice for some patients in resuscitation transplantation cycles.
Article
Endocrinology & Metabolism
Shi-Bin Chao, Yan-Hong Wang, Jian-Chun Li, Wen-Ting Cao, Yun Zhou, Qing-Yuan Sun
Summary: This study investigated the impact of a novel endometrial preparation approach (DROI) on the clinical pregnancy rate of single frozen-thawed blastocyst transfer and compared it with hormone replace treatment (HRT). The results showed that the DROI group had significantly higher clinical pregnancy rate and ongoing pregnancy rate compared to the HRT group, suggesting that DROI may be a more efficient and promising alternative for endometrial preparation in frozen-thawed blastocyst transfer.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Obstetrics & Gynecology
Reeva Makhijani, Prachi Godiwala, James Grady, Alicia Christy, Kim Thornton, Daniel Grow, Lawrence Engmann
Summary: This retrospective cohort study aimed to evaluate if racial/ethnic differences persist in pregnancy outcomes in frozen-thawed embryo transfer (FET) cycles. The results showed that Black women had a significantly lower live birth rate and implantation rate, as well as higher clinical loss rate compared to other racial/ethnic groups.
FERTILITY AND STERILITY
(2022)
Article
Obstetrics & Gynecology
Asaf Bilgory, Yael Kalma, Rotem Kopel, Foad Azem
Summary: Comparing clinical pregnancy rate (CPR) and live birth rate (LBR) after frozen-thawed embryo transfer (FET) of day (D-) 6 blastocysts on D-5 versus D-6, it was found that transferring embryos on D-5 produced significantly higher CPR and LBR values. The study suggests that transferring D-6 embryos on D-5 may lead to better outcomes than transferring them on D-6.
REPRODUCTIVE SCIENCES
(2021)
Article
Endocrinology & Metabolism
Jiangman Gao, Yifeng Yuan, Jia Li, Tian Tian, Ying Lian, Ping Liu, Rong Li, Jie Qiao, Xiaoyu Long, Haiyan Wang
Summary: Sequential embryo transfer in frozen-thawed embryo transfer cycles can improve the clinical outcomes of patients with RIF, including implantation rate, clinical pregnancy rate, and multiple pregnancy rate.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Endocrinology & Metabolism
Lin Song, Zhiqin Bu, Yingpu Sun
Summary: This study aimed to investigate the relationship between endometrial thickness and early pregnancy complications in frozen thawed embryo transfer cycles. The results showed that thin endometrium was associated with an increased risk of ectopic pregnancy and early spontaneous miscarriage. Therefore, endometrial thickness can serve as an independent predictor for early pregnancy complications.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Obstetrics & Gynecology
He Li, Xiaoxi Sun, Junyi Yang, Lu Li, Wenbi Zhang, Xiang Lu, Junling Chen, Hua Chen, Min Yu, Wei Fu, Xiandong Peng, Jiazhou Chen, Ernest Hung Yu Ng
Summary: The study compared immediate and delayed frozen embryo transfers following a stimulated IVF cycle and found that immediate FET resulted in significantly higher ongoing pregnancy and live birth rates. This suggests that immediate FET may be more effective after a stimulated IVF cycle.
HUMAN REPRODUCTION
(2021)
Article
Obstetrics & Gynecology
Adva Aizer, Meirav Noach-Hirsh, Olga Dratviman-Storobinsky, Ravit Nahum, Ronit Machtinger, Yuval Yung, Jigal Haas, Raoul Orvieto
Summary: This study examined the effect of COVID-19 infection or vaccination on frozen-thawed embryo transfer (FET), and found that these factors did not affect patients' performance or implantation in subsequent FET cycles.
FERTILITY AND STERILITY
(2022)
Article
Genetics & Heredity
Antonio Quartucci, Luca Pagliardini, Paolo Ivo Cavoretto, Alessandra Alteri, Edgardo Somigliana, Chiara Dallagiovanna, Paola Vigano, Annalisa Racca, Christophe Blockeel, Massimo Candiani, Enrico Papaleo, Valeria Stella Vanni
Summary: The study examined the association between serum progesterone levels at the day of ovulation trigger and neonatal birthweight in frozen-thawed embryo transfer cycles. The results showed an inverse correlation between serum progesterone levels and birthweight z-score of neonates. This study has important implications for guiding the embryo transfer process in assisted reproductive technology.
JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
(2023)
Article
Endocrinology & Metabolism
Zhonghua Zhao, Yan Chen, Hongxia Deng, Lu Huang, Danhua Lu, Xiaoyang Shen, Liangzhi Xu
Summary: A systematic review and meta-analysis found that the stage of embryo transfer had a significant impact on obstetric and perinatal outcomes in programmed frozen-thawed embryo transfer (FET) and natural FET cycles. Programmed FET cycles had higher risks of hypertensive disorders of pregnancy, gestational hypertension, preeclampsia, gestational diabetes mellitus, large for gestational age, macrosomia, preterm delivery, placenta previa, postpartum haemorrhage, and preterm premature rupture of membranes compared to natural FET cycles with overall embryo transfer and blastocyst transfer. However, there were no clear differences in outcomes between programmed FET cycles and natural FET cycles with cleavage-stage embryo transfer.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Endocrinology & Metabolism
Jian-Chun Li, Yan-Hong Wang, Li-Ying Peng, Yun Zhou, Shi-Bin Chao
Summary: The DROI protocol showed significantly higher implantation rate and clinical pregnancy rate compared to the mNC protocol in frozen-thawed embryo transfer, suggesting it may be a more efficient and promising approach for improving pregnancy outcomes.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Rehabilitation
Buse Ozcan Kahraman, Ismail Ozsoy, Turhan Kahraman, Aylin Tanriverdi, Serap Acar, Ebru Ozpelit, Bahri Akdeniz, Stephanie Hiser, Fernando Silva Guimaraes, Dale M. Needham, Sema Savci
DISABILITY AND REHABILITATION
(2020)
Review
Orthopedics
Julia Ribeiro Lemos, Felipe Amorim da Cunha, Agnaldo Jose Lopes, Fernando Silva Guimaraes, Fabricio Vieira do Amaral Vasconcellos, Patricia dos Santos Vigario
JOURNAL OF BACK AND MUSCULOSKELETAL REHABILITATION
(2020)
Letter
Cardiac & Cardiovascular Systems
Jannis Papathanasiou, Donka Dimitrova, Nigyar Dzhafer, Kostadin Kanalev, Yannis Dionyssiotis, Dorothea Tsekoura, Arthur Sa Ferreira, Fernando Silva Guimar, Agnaldo Jose Lopes
HELLENIC JOURNAL OF CARDIOLOGY
(2020)
Article
Immunology
Cynthia Louis, Fernando Souza-Fonseca-Guimaraes, Yuyan Yang, Damian D'Silva, Tobias Kratina, Laura Dagley, Soroor Hediyeh-Zadeh, Jai Rautela, Seth Lucian Masters, Melissa J. Davis, Jeffrey J. Babon, Bogoljub Ciric, Eric Vivier, Warren S. Alexander, Nicholas D. Huntington, Ian P. Wicks
JOURNAL OF EXPERIMENTAL MEDICINE
(2020)
Review
Immunology
Gustavo Rodrigues Rossi, Edvaldo S. Trindade, Fernando Souza-Fonseca-Guimaraes
FRONTIERS IN IMMUNOLOGY
(2020)
Article
Cell Biology
Caroline Natania de Souza-Araujo, Claudia Rodrigues Tonetti, Marcella Regina Cardoso, Liliana Aparecida Lucci de Angelo Andrade, Rodrigo Fernandes da Silva, Luis Gustavo Romani Fernandes, Fernando Guimaraes
Article
Biochemistry & Molecular Biology
Hui Yi Chew, Priscila O. De Lima, Jazmina L. Gonzalez Cruz, Blerida Banushi, Godwins Echejoh, Lingbo Hu, Shannon R. Joseph, Benedict Lum, James Rae, Jake S. O'Donnell, Lilia Merida de Long, Satomi Okano, Brigid King, Rachael Barry, Davide Moi, Roberta Mazzieri, Ranjeny Thomas, Fernando Souza-Fonseca-Guimaraes, Matthew Foote, Adam McCluskey, Phillip J. Robinson, Ian H. Frazer, Nicholas A. Saunders, Robert G. Parton, Riccardo Dolcetti, Katharine Cuff, Jennifer H. Martin, Benedict Panizza, Euan Walpole, James W. Wells, Fiona Simpson
Article
Biochemistry & Molecular Biology
Alex Ap. Rosini Silva, Marcella R. Cardoso, Luciana Montes Rezende, John Q. Lin, Fernando Guimaraes, Geisilene R. Paiva Silva, Michael Murgu, Denise Goncalves Priolli, Marcos N. Eberlin, Alessandra Tata, Livia S. Eberlin, Sophie F. M. Derchain, Andreia M. Porcari
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2020)
Correction
Immunology
Cynthia Louis, Fernando Guimaraes, Yuyan Yang, Damian D'Silva, Tobias Kratina, Laura Dagley, Soroor Hediyeh-Zadeh, Jai Rautela, Seth Lucian Masters, Melissa J. Davis, Jeffrey J. Babon, Bogoljub Ciric, Eric Vivier, Warren S. Alexander, Nicholas D. Huntington, Ian P. Wicks
JOURNAL OF EXPERIMENTAL MEDICINE
(2020)
Article
Oncology
Sarah A. Best, Jonas B. Hess, Fernando Souza-Fonseca-Guimaraes, Joseph Cursons, Ariena Kersbergen, Xueyi Dong, Jai Rautela, Stephanie R. Hyslop, Matthew E. Ritchie, Melissa J. Davis, Tracy L. Leong, Louis Irving, Daniel Steinfort, Nicholas D. Huntington, Kate D. Sutherland
JOURNAL OF THORACIC ONCOLOGY
(2020)
Review
Critical Care Medicine
Marcia S. Volpe, Fernando S. Guimaraes, Caio C. A. Morais
Article
Medicine, General & Internal
Gustavo R. Rossi, Jenifer P. Goncalves, Timothy McCulloch, Rebecca B. Delconte, Robert J. Hennessy, Nicholas D. Huntington, Edvaldo S. Trindade, Fernando Souza-Fonseca-Guimaraes
JOURNAL OF CLINICAL MEDICINE
(2020)
Article
Oncology
Qiutong Huang, Nicolas Jacquelot, Adele Preaudet, Soroor Hediyeh-zadeh, Fernando Souza-Fonseca-Guimaraes, Andrew N. J. McKenzie, Philip M. Hansbro, Melissa J. Davis, Lisa A. Mielke, Tracy L. Putoczki, Gabrielle T. Belz
Summary: Colorectal cancer is the second leading cause of cancer-related deaths globally. The study shows that specialized type 2 innate lymphoid cells (ILC2) infiltrate colorectal tumors and their presence is associated with reduced tumor burden and improved overall survival. This highlights the potential of ILC2 as a new therapeutic approach to improve clinical outcomes in colorectal cancer.
Article
Biology
Hebert Olimpio Junior, Agnaldo Jose Lopes, Fernando Silva Guimaraes, Sergio Luiz Soares Marcos da Cunha Chermont, Sara Lucia Silveira de Menezes
Summary: The Glittre-ADL test (GA-T) is a functional capacity test that includes multiple tasks similar to activities of daily living. This study found that the total GA-T time can be used to estimate ventilatory efficiency in patients with CHF. Future research could combine GA-T with other functional capacity tests to guide treatment plans and evaluate prognosis.
BMC RESEARCH NOTES
(2021)
Review
Hematology
Cheng-Yu Lin, Ilan Gobius, Fernando Souza-Fonseca-Guimaraes
SEMINARS IN HEMATOLOGY
(2020)