Design and synthesis of a series of bioavailable fatty acid synthase (FASN) KR domain inhibitors for cancer therapy

Published 2018 View Full Article

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Title
Design and synthesis of a series of bioavailable fatty acid synthase (FASN) KR domain inhibitors for cancer therapy
Authors
Keywords
Fatty acid synthase, Enzyme inhibitor, X-ray crystal structure, Cell proliferation, SAR, Cancer
Journal
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 28, Issue 12, Pages 2159-2164
Publisher
Elsevier BV
Online
2018-05-09
DOI
10.1016/j.bmcl.2018.05.014

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