Molecular determinants of loperamide and N -desmethyl loperamide binding in the hERG cardiac K + channel

Published 2018 View Full Article

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Title
Molecular determinants of loperamide and N -desmethyl loperamide binding in the hERG cardiac K + channel
Authors
Keywords
Loperamide, N, -Desmethyl loperamide, hERG, KvLQT1, mink, Nav1.5, QT prolongation, QRS prolongation, Cryo-EM docking
Journal
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 28, Issue 3, Pages 446-451
Publisher
Elsevier BV
Online
2017-12-15
DOI
10.1016/j.bmcl.2017.12.020

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