Article
Oncology
Boris Jansen-Winkeln, Michelle Dvorak, Hannes Koehler, Marianne Maktabi, Matthias Mehdorn, Claire Chalopin, Michele Diana, Ines Gockel, Manuel Barberio
Summary: Good bowel oxygenation is crucial for anastomotic healing after colorectal resections. Hyperspectral imaging has the potential to be used as a clinical tool for assessing tissue oxygenation during surgery, as shown in this study involving 105 patients.
Article
Medicine, General & Internal
Eberhard Grambow, Niels Arne Sandkuehler, Justus Gross, Daniel G. E. Thiem, Michael Dau, Matthias Leuchter, Malte Weinrich
Summary: This study investigated the feasibility of using hyperspectral imaging (HSI) to monitor skin oxygenation in patients with peripheral artery disease (PAD). The results showed that HSI can be used as an additional technique to assess tissue oxygen saturation in PAD patients, and it is robust to external confounders such as temperature and physical activity.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Health Care Sciences & Services
Diana Heimes, Philipp Becker, Daniel G. E. Thiem, Robert Kuchen, Solomiya Kyyak, Peer W. Kaemmerer
Summary: This study found a strong correlation between HSI and MAT in assessing collateral perfusion, with HSI proving to reliably differentiate between perfusion and occlusion. The results suggest that HSI could be a useful tool for non-medical personnel and provide an objective and reproducible method for assessing collateral perfusion.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Review
Biology
Anouk A. M. A. Lindelauf, Alexander G. Saelmans, Sander M. J. van Kuijk, Rene R. W. J. van der Hulst, Rutger M. Schols
Summary: Non-invasive optical methods such as near-infrared spectroscopy (NIRS) and hyperspectral imaging (HSI) have shown to be reliable and accurate for monitoring vascular compromise in reconstructive flap surgery. However, based on the currently available literature, no firm conclusions can be drawn regarding the superiority of non-invasive monitoring techniques.
Article
Medicine, General & Internal
Philipp Becker, Sebastian Blatt, Andreas Pabst, Diana Heimes, Bilal Al-Nawas, Peer W. Kaemmerer, Daniel G. E. Thiem
Summary: This study showed that hyperspectral imaging can effectively monitor the perfusion status of MFF, especially through StO(2) and NPI. After 40 minutes, flap perfusion decreased due to the general aggravation of hemodynamic circulatory situation, resulting in a significant drop of StO(2) (p < 0.005) and NPI (p < 0.005), while the Doppler signal remained unchanged.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Multidisciplinary Sciences
Alexander Studier-Fischer, Silvia Seidlitz, Jan Sellner, Marc Bressan, Berkin Oezdemir, Leonardo Ayala, Jan Odenthal, Samuel Knoedler, Karl-Friedrich Kowalewski, Caelan Max Haney, Gabriel Salg, Maximilian Dietrich, Hannes Kenngott, Ines Gockel, Thilo Hackert, Beat Peter Mueller-Stich, Lena Maier-Hein, Felix Nickel
Summary: This publication releases HeiPorSPECTRAL, the first annotated high-quality standardized surgical HSI dataset, comprising 5758 spectral images and annotations of 20 physiological porcine organs. This dataset is expected to have wide applications in medical imaging research and future studies.
Article
Critical Care Medicine
Joerg Marotz, Torsten Schulz, Sebastian Seider, Diogo Cruz, Ahmed Aljowder, Dominik Promny, Georg Daeschlein, Thomas Wild, Frank Siemers
Summary: Hyperspectral imaging combined with advanced data processing can provide detailed visualization of perfusion characteristics of burn wounds, leading to the development of a more reliable classification system for burn degrees.
Article
Health Care Sciences & Services
Daniel G. E. Thiem, Paul Roemer, Sebastian Blatt, Bilal Al-Nawas, Peer W. Kaemmerer
Summary: Hyperspectral imaging (HSI) was found to detect compromised perfusion in free flaps significantly earlier than clinical monitoring, providing clinicians with a tool to simplify postoperative flap monitoring.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Article
Acoustics
Vinh T. Pham, M. A. R. K. Ciccaglione, David G. Ramirez, Richard K. P. Benninger
Summary: The researchers previously found that measurements of pancreas perfusion dynamics can predict disease progression in type 1 diabetes (T1D). Now they tested whether these measurements can predict the success of therapeutic prevention of T1D.
ULTRASOUND IN MEDICINE AND BIOLOGY
(2022)
Article
Peripheral Vascular Disease
M. Dietrich, S. Marx, M. von der Forst, T. Bruckner, F. C. F. Schmitt, M. O. Fiedler, F. Nickel, A. Studier-Fischer, B. P. Mueller-Stich, T. Hackert, T. Brenner, M. A. Weigand, F. Uhle, K. Schmidt
Summary: This study utilized hyperspectral imaging (HSI) technology to evaluate tissue oxygenation and perfusion in healthy volunteers and septic patients, revealing distinctive microcirculatory patterns in septic patients, potentially opening new perspectives for microcirculatory monitoring in critically ill patients.
MICROVASCULAR RESEARCH
(2021)
Article
Surgery
Alexander G. Athey, Cody C. Wyles, Brian T. Carlsen, Kevin Perry, Matthew T. Houdek, Steven L. Moran
Summary: Free flap coverage following total knee arthroplasty, while rare, showed improvement in functional outcomes postoperatively, with a high rate of reoperation for complications.
PLASTIC AND RECONSTRUCTIVE SURGERY
(2021)
Article
Medicine, General & Internal
Tim Pruimboom, Anouk A. M. A. Lindelauf, Eric Felli, John H. Sawor, An E. K. Deliaert, Rene R. W. J. van der Hulst, Mahdi Al-Taher, Michele Diana, Rutger M. Schols
Summary: Hyperspectral imaging (HSI) is a novel imaging technique that can accurately assess tissue perfusion and differentiate between vital and necrotic skin flaps in breast reconstruction surgery. StO(2)% was found to be the most sensitive parameter for detecting flap necrosis.
Article
Dentistry, Oral Surgery & Medicine
D. G. E. Thiem, R. W. Frick, E. Goetze, M. Gielisch, B. Al-Nawas, P. W. Kaemmerer
Summary: In reconstructive surgery, flap monitoring is crucial for early identification of perfusion problems. This clinical study aimed to develop a non-invasive, objective approach for perfusion monitoring of free and pedicled flaps using hyperspectral imaging. The study found differences in parameters such as StO(2), NIR, THI, and TWI over time, with specific thresholds indicating arterial or venous perfusion issues. Results showed that pedicled flaps had decreased perfusion parameters compared to free flaps after transfer but remained similar later on.
CLINICAL ORAL INVESTIGATIONS
(2021)
Article
Anesthesiology
Simone F. Kleiss, Kirsten F. Ma, Mostafa El Moumni, Richte C. L. Schuurmann, Clark J. Zeebregts, Marieke Haalboom, Reinoud P. H. Bokkers, Jean-Paul P. M. de Vries
Summary: This study demonstrated good short term test-retest reliability for HSI measurements on the lower extremity, but low intra- and inter-observer reliability was observed when performed on different days. The reliability of HSI can be improved by averaging two measurements taken on different days.
JOURNAL OF CLINICAL MONITORING AND COMPUTING
(2022)
Article
Chemistry, Analytical
Iestyn Pope, Francesco Masia, Kenneth Ewan, Ana Jimenez-Pascual, Trevor C. Dale, Florian A. Siebzehnrubl, Paola Borri, Wolfgang Langbein
Summary: Quantitative hyperspectral coherent Raman scattering microscopy combines imaging with spectroscopy to extract physically meaningful chemical components with sub-cellular resolution. This label-free method can discriminate different cellular sub-populations and has potential for non-invasive disease diagnostics.