Article
Biochemistry & Molecular Biology
Piotr Duchnowicz, Radoslaw Pilarski, Jaromir Michalowicz, Bozena Bukowska
Summary: Extracts from Uncaria tomentosa affect the morphology and membrane properties of human erythrocytes. The compounds mainly incorporate into the outer hydrophilic monolayer of the erythrocyte membrane, providing protection against oxidative stress.
Article
Chemistry, Multidisciplinary
Federica Arrigo, Francesca Arfuso, Federica Impellitteri, Claudia Giannetto, Giuseppe Piccione, Caterina Faggio
Summary: The aim of this study was to investigate the effects of two xenobiotics (Quaternium-15 and Thiacloprid) on the haematological profile and erythrocyte osmotic fragility (EOF) of equine and bovine blood samples. The results showed that exposure to the xenobiotics resulted in a decrease in red blood cells, white blood cells, haematocrit, haemoglobin, mean corpuscular volume, and platelets, as well as an increase in EOF. This study emphasizes the concept that blood cells are an excellent target for evaluating the effects of xenobiotics.
APPLIED SCIENCES-BASEL
(2023)
Article
Nutrition & Dietetics
Ciara Lundy, Samantha N. Fessler, Carol S. Johnston
Summary: The study found no relationship between vitamin C status and erythrocyte osmotic fragility in adults with well-controlled T2D.
FRONTIERS IN NUTRITION
(2022)
Article
Physiology
Ankie M. van Cromvoirt, Simone Fenk, Ario Sadafi, Elizaveta V. Melnikova, Denis A. Lagutkin, Kuntal Dey, Irina Yu. Petrushanko, Inga Hegemann, Jeroen S. Goede, Anna Bogdanova
Summary: The deformability, lifespan, and rheological properties of red blood cells (RBCs) depend on factors such as cell deformability, hydration, and membrane stability. Age and gender may influence RBC parameters, with RBC age potentially affecting osmoscan parameters. Further studies are needed to validate age-stratified reference values for clinical practice.
FRONTIERS IN PHYSIOLOGY
(2021)
Article
Multidisciplinary Sciences
Md. Shoriful Islam, Mst. Shahnaj Parvin, Md. Ekramul Islam
Summary: The extract from Hygrophila schulli seeds demonstrated significant antioxidant activity, protecting DNA and red blood cells from oxidative damage and offering potential health benefits. This study confirms that the extract can be used as a functional food or nutraceutical product.
Article
Biochemistry & Molecular Biology
Bernard Omokheshi Adele, Chidimma Idama, Abayomi O. Ige, Anthony Olusoji Odetola, Idara Emmanuel Emediong, Elsie Olufunke Adewoye
Summary: Toxic copper exposure alters erythrocyte membrane deformability and fluidity by disrupting membrane lipid composition, saturation, fatty acid profile, and permeability. Exposure to toxic copper level leads to increased phospholipids levels and instability in the erythrocyte membrane, as well as changes in cholesterol/phospholipid ratio and fatty acid composition.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2023)
Article
Chemistry, Physical
Sylwia Cyboran-Mikolajczyk, Robert Paslawski, Urszula Paslawska, Kacper Nowak, Michal Plociennik, Katarzyna Meczarska, Jan Oszmianski, Dorota Bonarska-Kujawa, Pawel Kowalczyk, Magdalena Wawrzynska
Summary: Long-term high fat-carbohydrates diet can lead to irreversible changes in the body, affecting the physical properties of erythrocytes. Extracts of Cistus incanus L. have been shown to mitigate the effects of high fat diet on erythrocytes through membrane-modifying and antioxidant activities.
Article
Veterinary Sciences
Sophia A. Morse, Erin T. Mooney
Summary: Comparing fresh and stored feline red blood cells after passage through a microaggregate filter showed no significant injury in fresh RBCs. Stored blood exhibited changes in hemolysis percentage, red cell distribution width, and hematocrit, possibly induced by the filter. Further research is needed to assess the impact of transfusion technique on storage lesion in feline blood.
JOURNAL OF FELINE MEDICINE AND SURGERY
(2022)
Article
Cell Biology
J. S. Sudnitsyna, E. A. Skverchinskaya, I. M. Zubina, E. D. Suglobova, T. D. Vlasov, A. Smirnov, A. V. Vasiliev, T. O. Ruzhnikova, B. A. Kaljuzhnyi, I. Mindukshev, Yu A. Borisov
Summary: ESRD is associated with various erythrone alterations, including increased osmotic fragility and swelling rate of erythrocytes, as well as oxidation of hemoglobin to ferryl forms after HD sessions. These changes, combined with uremic syndrome and mechanical effects of HD, contribute to decreased erythrocyte function and exacerbation of renal anemia.
BIOLOGICHESKIE MEMBRANY
(2021)
Article
Cell Biology
J. S. Sudnitsyna, E. A. Skverchinskaya, I. M. Zubina, E. D. Suglobova, T. D. Vlasov, A. Smirnov, A. N. Vasiliev, T. O. Ruzhnikova, B. A. Kaljuzhnyi, I. Mindukshev, Yu A. Borisov
Summary: End-stage renal disease (ESRD) is associated with structural and functional changes in red blood cells (RBCs), which are potential risk factors for causing RBC malfunctions and anemia. This study investigated the effects of hemodialysis (HD) on RBCs and found that HD can lead to oxidative stress and apoptosis-like events in RBCs, contributing to the aggravation of renal anemia.
BIOCHEMISTRY MOSCOW SUPPLEMENT SERIES A-MEMBRANE AND CELL BIOLOGY
(2022)
Article
Agriculture, Multidisciplinary
Gavirangappa Hithamani, Krishnapura Srinivasan
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2017)
Article
Biochemistry & Molecular Biology
Susmita Barman, Krishnapura Srinivasan
BIOLOGICAL TRACE ELEMENT RESEARCH
(2019)
Article
Ophthalmology
Seetur R. Pradeep, Krishnapura Srinivasan
CURRENT EYE RESEARCH
(2018)
Article
Biochemistry & Molecular Biology
Susmita Barman, Seetur R. Pradeep, Krishnapura Srinivasan
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2018)
Article
Biochemistry & Molecular Biology
Seetur R. Pradeep, Krishnapura Srinivasan
Article
Nutrition & Dietetics
Seetur R. Pradeep, Susmita Barman, Krishnapura Srinivasan
Article
Cardiac & Cardiovascular Systems
Seetur R. Pradeep, Krishnapura Srinivasan
CARDIOVASCULAR TOXICOLOGY
(2018)
Article
Medicine, Research & Experimental
Ravula Venkatesh, Krishnapura Srinivasan, Sridevi Annapurna Singh
BIOMEDICINE & PHARMACOTHERAPY
(2017)
Article
Nutrition & Dietetics
Seetur R. Pradeep, Krishnapura Srinivasan
APPLIED PHYSIOLOGY NUTRITION AND METABOLISM
(2017)
Review
Medicine, Research & Experimental
Weizhuo Lu, Zhiwu Chen, Jiyue Wen
Summary: Ischemic stroke is a common and serious disease, and neuroinflammation plays a crucial role in its progression. Microglia, astrocytes, and infiltrating immune cells are involved in the complicated neuroinflammation cascade, releasing different molecules that affect inflammation. Flavonoids, plant-specific compounds, have shown protective effects against cerebral ischemia injury by modulating the inflammatory responses.
BIOMEDICINE & PHARMACOTHERAPY
(2024)